目录
更新日期:2026年9月10日
姓 名 黄巧冰 性 别
民 族 汉族 导师层次 博士导师
技术职称 教授 导师类型 学术型
最后学历 博士研究生毕业 最后学位 哲学博士学位
行政职务 Email bing@smu.edu.cn
工作单位 南方医科大学基础医学院 邮政编码 510515
个人简介

   黄巧冰,南方医科大学基础医学院病理生理教研室教授,博士生导师,国家级教学名师,南粤优秀教师,广东省教学名师,广东省特支计划”教学名师”,广东省师德师风先进个人,南方医科大学本科教学优秀教师,南方医科大学教指委主委。科研工作主要关注疾病发生过程中内皮细胞功能变化的作用和机制以及脓毒症器官功能衰竭的发生机制。先后主持9项国家自然科学基金项目,发表研究论文160余篇,其中第一和通讯作者发表SCI收录研究论文60余篇。现任中国微循环学会第六届副理事长,中国病理生理学会微循环专业委员会主任委员,中国病理生理学会常务理事,广东省病理生理学会监事长等。是Frontiers in Physiology Vascular Physiology 副主编,任中国病理生理杂志常务编委,微循环学杂志副主编,是多家国内中英文杂志的编委,担任多本国际杂志审稿人。

研究领域

糖尿病血管并发症发生的内皮细胞机制

脓毒症(感染性休克)器官功能障碍的发生机制

个人成果

近5年以通讯和共同通讯发表的SCI收录论文:

1. Huang X, Liu Z, Hu J, Li B, Chen Z, Zeng T, Zhou X, Lu R, Deng W, Zhou W, Huang Q*. Increased CD44 Expression in Endothelial Cells Induced by Advanced Glycation End Products Leads to Insufficient Maturation of Angiogenesis. J Cell Mol Med. 2026 Mar,30(6):e71088.

2. Hu J, Liu Z, Huang X, Li B, Chen Z, Zeng T, Zhou X, Huang Q*. The phosphorylation of moesin impairs the integrity of vascular basement membrane in pathological angiogenesis. Exp Cell Res. 2025 Jul 7;450(2):114668. 

3. Sun M, Li Y, Xu G, Zhu J, Lu R, An S, Zeng Z, Deng Z, Cheng R, Zhang Q, Yao Y, Wu J, Zhang Y, Hu H, Chen Z*, Huang Q*, Wu J*. SIRT3-mediated OPA1 deacetylation protects against sepsis-induced acute lung injury by inhibiting alveolar macrophage pro-inflammatory polarization. Antioxid Redox Signal. 2024 Dec;41(16-18):1014-1030.

4. Liu J#, Song K#, Lin B, Chen Z, Zuo Z, Fang Y, He Q, Yao X, Liu Z*, Huang Q*, Guo X*. HMGB1 promotes neutrophil PD-L1 expression through TLR2 and mediates T cell apoptosis leading to immunosuppression in sepsis. Int Immunopharmacol. 2024 May 30;133:112130.

5. Liu J, Song K, Lin B, Chen Z, Liu Y, Qiu X, He Q, Zuo Z, Yao X, Huang X, Liu Z, Liu Z*, Huang Q*, Guo X*. The suppression of HSPA8 attenuates NLRP3 ubiquitination through SKP2 to promote pyroptosis in sepsis-induced lung injury. Cell Biosci. 2024 May 2;14(1):56.  

6. Zhang Q, Liu Z, Huang X, Heng X, Wu J, Chen Z, Guo X, Fan J*, Huang Q*. Mdivi-1 alleviates sepsis-induced liver injury by inhibiting STING signaling activation. Shock . 2024 Jul 1;62(1):95-102.  

7. Sun M, Zeng Z, Xu G, An S, Deng Z, Cheng R, Yao Y, Wu J, Hu H, Huang Q*, Wu J*. Promoting mitochondrial dynamic equilibrium attenuates sepsis-induced acute lung injury by inhibiting pro-inflammatory polarization of alveolar macrophages. Shock. 2023 Oct 1;60(4):603-612.

8. He Q, Zuo Z, Song K, Wang W, Yu L, Tang Z, Hu S, Li L, Luo H, Chen Z, Liu J, Lin B, Luo J, Jiang Y*, Huang Q*, Guo X*. Keratin7 and Desmoplakin are involved in acute lung injury induced by sepsis through RAGE. Int Immunopharmacol. 2023 Nov;124(Pt A):110867.

9. Huang X#, Li B#, Hu J, Liu Z, Li D, Chen Z, Huang H, Chen Y, Guo X, Cui Y, Huang Q*. Advanced glycation endproducts mediate chronic kidney injury with characteristic patterns in different stages. Front Physiol. 2022 Sep 9;13:977247.  

10. Li B#, Huang X#, Wei J, Huang H, Liu Z, Hu J, Zhang Q, Chen Y, Cui Y, Chen Z, Guo X, Huang Q*. Role of moesin and its phosphorylation in VE-cadherin expression and distribution in endothelial adherens junctions. Cell Signal. 2022 Sep 10:110466.

11. Zhang Q, Wei J, Liu Z, Huang X, Sun M, Lai W, Chen Z, Wu J, Chen Y, Guo X, Huang Q*. STING signaling sensing of DRP1-dependent mtDNA release in kupffer cells contributes to lipopolysaccharide-induced liver injury in mice. Redox Biol. 2022 Jun 15;54:102367. 

12. Mao L#, Sun M#, Chen Z, Zeng Z, Wu J, Chen Z*, Zhang W*, Huang Q*. The Pyruvate Dehydrogenase Complex Mitigates LPS-Induced Endothelial Barrier Dysfunction by Metabolic Regulation. Shock. 2022 Jun 1;57(6):308-317. 

13. Zou Z#, Li L#, Li Q, Zhao P, Zhang K, Liu C, Cai D, Maegele M*, Gu Z*, Huang Q*. The role of S100B/RAGE-enhanced ADAM17 activation in endothelial glycocalyx shedding after traumatic brain injury. J Neuroinflammation. 2022 Feb 11;19(1):46. doi: 10.1186/s12974-022-02412-2. 

14. Chen Y, Liu Z, Chen H, Huang X, Huang X, Lei Y, Liang Q, Wei J, Zhang Q, Guo X, Huang Q*. p53 SUMOylation Mediates AOPP-Induced Endothelial Senescence and Apoptosis Evasion. Front Cardiovasc Med. 2022 Feb 3;8:795747.  

15. Sun M#, Li J#, Mao L, Wu J, Deng Z, He M, An S, Zeng Z*, Huang Q*, Chen Z*. p53 Deacetylation Alleviates Sepsis-Induced Acute Kidney Injury by Promoting Autophagy. Front Immunol. 2021 Jul 14;12:685523.