论文：

1. Xiaopu Lin, Xiaoming Wen, Yanting Zhou, Junxi Wu, Zhiyang Lu, Lingling Xu. Lower Limb Bone Mineral Density Reduction is Closely Relative With Diabetic Peripheral Neuropathy in the Postmenopausal Women and Men Over 50 Years Old With T2DM: A cross-Sectional, Controlled Study. Calcif Tissue Int. 2025;116(1):83.

2. Wenhui Liu, Huren Zou, Danming You, Huijie Zhang, Lingling Xu. Sodium Houttuybonate Promotes the Browning of White Adipose Tissue by Inhibiting Ferroptosis via the AMPK-NRF2-HO1 Pathway. Oxidants (Basel). 2024;13(9):1057.

3.  Jingyi Zhong, Xiaopu Lin, Xiaobin Zheng, Yanting Zhou, Haishan Huang, Lingling Xu. Diminished levels of insulin-like growth factor-1 may be a risk factor for peripheral neuropathy in type 2 diabetes patients. J Diabetes Investig. 2024;15(9):1259-1265.

4.  Lina Wang, Xiaopu Lin, Haishan Huang, Yanfang Wang, Xinxin Liang, Xiaobin Zheng, Lingling Xu. Low rectus femoris mass index is closely associated with diabetic peripheral neuropathy. Front Endocrinol (Lausanne). 2023;14:1148093.

5.   Haishan Huang, Xiaobin Zheng, Xiaoming Wen, Jingyi Zhong, Yanting Zhou, Lingling Xu. Visceral fat correlates with insulin secretion and sensitivity independent of BMI and subcutaneous fat in Chinese with type 2 diabetes. Front Endocrinol (Lausanne) 2023;14:1144834.

6.  Xiaopu Lin, Zhenguo Chen, Haishan Huang, Jingyi Zhong, Lingling Xu. Diabetic kidney disease progression is associated with decreased lower-limb muscle mass and increased visceral fat area in T2DM patients. Front Endocrinol (Lausanne). 2022,13:1002118

7.  Haishan Huang, Jing Jin, Yanshan Chen, Lina Wang, Jingyi Zhong, Zhenguo Chen, Lingling Xu. Visceral fat might impact left ventricular remodeling through changes in arterial stiffness in type 2 diabetes: A cross-sectional study. Int J Cardiol. 2022, S0167-5273(22) 01198-6.

8.  Xiaopu Lin, Chuna Chen,Yingshan Liu,Yu Peng, Zhenguo Chen, Haishan Huang, Lingling Xu. Peripheral Nerve Conduction And Sympathetic Skin Response Are Reliable Methods to Detect Diabetic Cardiac Autonomic Neuropathy. Front Endocrinol (Lausanne) 2021, 21;12:709114.

9.  Yu Peng, Ying-shan Liu, Min-yi Wu, Chu-na Chen, Chu-qiao Li, An-qi Jiang, Chong-xin Li, Yao Wang, Ge Tian, Su-yue Pan, Lingling Xu. Evaluation of the Degree of Agreement of Four Methods for Diagnosing Diabetic Autonomic Neuropathy. Front. Neurol. 2021, 12:637099.

10.  Jing Jin, Xinxin Liang, Jie Wei, Lingling Xu. A New Mutation of the INSR Gene in a 13-Year-Old Girl with Severe Insulin Resistance Syndrome in China. Biomed Res Int. 2021, 2021:8878149.

11.  Yingshan Liu, Yu Peng, Jing Jin,Yanshan Chen, Chuna Chen, Zhenguo Chen, Haishan Huang, Lingling Xu. Insulin Resistance is Independently Associated with Cardiovascular Autonomic Neuropathy in Type 2 Diabetes. J Diabetes Investig.2021,12(9):1651-1662.

12.  Yingshan Liu, Jing Jin, Yanshan Chen, Chuna Chen, Lingling Xu. Integrative analyses of biomarkers and pathways for adipose tissue after bariatric surgery. Adipocyte. 2020, 9(1):384-400.

13.  Yingshan Liu, Chuna Chen, Zhenguo Chen, Yu Peng, XiaoPu Lin, Lingling Xu. Vascular and Metabolic Effects of Metformin Added to Insulin Therapy in Patients With Type 1 Diabetes: A Systematic Review and Meta-Analysis. Diabetes Metab Res Rev. 2020,36(6):e3334. 

14.  Xiaoyun Zeng, Xiaoming Wen, Xinxin Liang, Lina Wang, Lingling Xu. A case report of Proteus syndrome (PS). BMC Med Genet. 2020, 21(1):15.

15.  Lingling Xu, Xiaopu Lin, Meiping Guan, Yanmei Zeng, Yingshan Liu. Verapamil Attenuated Prediabetic Neuropathy in High-Fat Diet-Fed Mice through Inhibiting TXNIP-Mediated Apoptosis and Inflammation. Oxidative medicine and cellular longevity. 2019, 2019: 1896041.

16.  Lingling Xu, Xiaopu Lin, Meiping Guan, Yingshan Liu. Correlation Between Different Stages of Diabetic Nephropathy and Neuropathy in Patients with T2DM: A Cross-Sectional Controlled Study. Diabetes Ther. 2018, 9(6): 2335-2346.

17.  Xiaopu Lin, Lingling Xu, Deqiang Zhao, Zhiyin Luo, Suyue Pan. Correlation between.serum uric acid and diabetic peripheral neuropathy in T2DM patients. J Neurol Sci. 2018, 385: 78-82.

18.  Lingling Xu, Linna Li, Cuihua Xie, Meiping Guan, Yaoming Xue. Thickness of extraocular muscle and orbital fat in MRI predicts response to glucocorticoid therapy in Graves’ opthalmopathy. International Journal of Endocrinology. 2017, 2017: 3196059.

19.  Lingling Xu, Shiqun Liu, Meiping Guan, Yaoming Xue. Comparison of prednisolone, etoricoxib, and indomethacin in treatment of acute gouty arthritis: an open-label, randomized, controlled trial. Med Sci Monit. 2016, 22: 810-817. 

20.  Lingling Xu, Dou Tang, Meiping Guan, Cuihua Xie, Yaoming Xue. Effect of high-fat diet on peripheral neuropathy in C57BL/6 mice. International Journal of Endocrinology. 2014, 2014: 305205.

 课题：

1. 国家自然科学基金面上项目，82570952，神经元和巨噬细胞间mtDNA/线粒体的转移在高糖所致DPN的免疫炎症机制及修复作用研究，2026/01-2029/12,49万元，在研，主持。

2. 深圳市医学研究专项资金，C2401034，司美格鲁肽治疗2型糖尿病周围神经病变的实用性随机对照临床试验，2025/01-2028/12，200万元，在研，主持。

3. 国家高性能医疗器械创新中心开放基金，NMED2023AGP-004，2型糖尿病住院患者不同时相胰岛素分泌与TIR的相关性研究，2023/06-2025/05，5万元，在研，主持。

4. 国家自然科学基金面上项目，82270895，基于TXNIP的O-GlcNAc修饰致线粒体代谢稳态失衡探讨高脂诱导糖尿病前期周围神经病变及其机制，2023/01-2026/12，52万元，在研，主持。

5. 深圳市科技计划项目基础研究（面上项目），JCYJ20220530154205012，O-GlcNAc修饰致TXNIP线粒体易位在高脂诱导糖尿病前期周围神经病变中的作用机制，2022/10-2025/10，15万元，在研，主持。

6. 深圳市科技计划项目基础研究（面上项目），JCYJ20210324130204011，CaV1.2激活介导内质网应激-细胞焦亡在糖尿病前期周围神经病变中的作用及机制，2021/10-2024/10，20万元，结题，主持。

7. 中华国际医学交流基金会2021年中国内分泌代谢英才研究项目，2021-N-03，CaV1.2激活介导内质网应激-细胞焦亡在糖尿病前期周围神经病变中的作用及机制，2021/12-2023/12.10万元，结题，主持。

8.  广东省自然科学基金自由申请项目，2016A030313521，TXNIP细胞内穿梭诱导炎症反应在糖尿病前期周围神经病变中的作用及机制研究，2016/06-2019/06，10万元，结题，主持。

9. 国家自然科学基金青年科学基金项目，81500656，TXNIP线粒体穿梭导致NLRP3炎症体激活在糖尿病前期周围神经病变中的作用及机制研究，2016/01- 2018/12，18万元，结题，主持。

10. 广东省自然科学基金博士启动项目，10451051501005781，高脂血症对糖尿病神经病变的作用及机制研究，2010/10-2012/10，3万元，结题，主持。