于博
医学博士，主任医师，学术型及专业型博士/硕士生导师，博士后合作导师；南方医科大学珠江医院创伤骨科副主任，广东省杰出青年医学人才。
学术任职：
德国弗莱堡大学医学院、美国哈佛大学医学院访问学者。中国复合材料学会生物复合材料专业委员会委员、中国科技部国家科技专家库成员，中国医药教育骨科专业委员会广东省骨科分会委员、中国科技部国家科技专家库成员、广东省创伤骨科学会青年委员、广东省医师协会骨关节外科学会青年委员 广东省医学会创伤骨科分会青年委员会副主任委员，广东省创伤骨科学会青年委员会副主任委员 、广东省实力中青年医师上榜专家。
研究方向：
致力于骨材料科学与骨组织工程支架的相关研究，共发表SCI论文26篇，其中以第一作者及通讯作者（包括共同第一和共同通讯作者）于《Carbohydrate Polymers》，《Theranostics》，《Journal of Materials Chemistry B 》等杂志发表SCI论文20余篇，累计影响因子115.422，最高IF=11.556，总被引次数522次，公开发明专利10项，并获得国家自然科学基金3项，广东省科学自然基金等。
[1] Chen Y, Liang Y, Jiang P, et al. Lipid/PLGA Hybrid Microbubbles as a Versatile Platform for Noninvasive Image-Guided Targeted Drug Delivery[J]. ACS applied materials & interfaces, 2019, 11(45): 41842-41852. (SCI, IF=8.45)
[2] Yong Gong#, Songjian Li#, Rui Liu, Jianfeng Zhan, Chao Tan, Yifei Fang, Yan Chen*, Bo Yu*. Inhibition of YAP with siRNA prevents cartilage degradation and ameliorates osteoarthritis development[J]. Journal of Molecular Medicine, 2019, 97(1): 103-114. (SCI, IF=4.94)
[3] Yong Gong#, Songjian Li#, Wei Zeng, Jianing Yu, Yan Chen*, Bo Yu*. Controlled in vivo bone formation and vascularization using ultrasound-triggered release of recombinant vascular endothelial growth factor from PLGA microbubbles[J]. Frontiers in Pharmacology, 2019, 10: 413. (SCI, IF=3.8)
[4] Rui Liu#, Yan Chen#, Lanlan Liu#, Yong Gong#, Mingbo Wang, Songjian Li*, Changsheng Chen*, Bo Yu*. Long-term delivery of rhIGF-1 from biodegradable poly (lactic acid)/hydroxyapatite@ Eudragit double-layer microspheres for prevention of bone loss and articular degeneration in C57BL/6 mice[J]. Journal of Materials Chemistry B, 2018, 6(19): 3085-3095. (SCI, IF=4.47)
[5] Yan Chen#, Xujie Liu#, Rui Liu#, Yong Gong, Mingbo Wang, Qianli Huang, Qingling Feng*, Bo Yu*. Zero-order controlled release of BMP2-derived peptide P24 from the chitosan scaffold by chemical grafting modification technique for promotion of osteogenesis in vitro and enhancement of bone repair in vivo. Theranostics, 2017, 7(5): 1072. (SCI, IF=8.85)
[6] Yan Chen#, Rui Liu#, Yong Gong, Xixi Wu, Zhi Huang, Chao Dong, Chentian Li, Bo Yu*, The ultrasound elastic imaging monitoring of the injectable chitosan/nano-hydroxYAPatite/collagen bone scaffolds and comparisons with micro-CT and histological changes, Journal of Biomaterials and Tissue Engineering, 2016,1 (SCI, IF=2.07)
[7] Rui Liu#, Xixi Wu#, Jiyan Li, Xujie Liu, Zhi Huang, Yue Yuan, Xiaoying Gao, Bomiao Ling, Bo Yu*, Yan Chen*, The promotion of bone tissue regeneration by BMP2-derived peptide P24-loaded calcium phosphate cement microspheres, Ceramics International, 2016, 42(2): 3177–3189. (SCI, IF= 2.60)
[8] Li X*, Liu W, Sun L, Aifantis KE, Bo Yu*, Fan Y*, Feng Q, Cui F, Watari F 2014. Effects of physicochemicalproperties of nanomaterials on their toxicity. J Biomed Mater Res Part A,2015, 103(7): 2499-2507. (SCI, IF=3.37)
[9] Fupo He#, Yan Chen#, Jiyan Li, Bomiao Lin, Yi Ouyang, Bo Yu, Yuanyou Xia, Bo Yu*, Jiandong Ye*. Improving bone repair of femoral and radial defects in rabbit by incorporating PRP into PLGA/CPC composite scaffold with unidirectional pore structure. J Biomed Mater Res Part A 2015:103A:1312–1324.（SCI, IF=3.37）
[10] Zhi Huang#, Bo Yu#, Qingling Feng*, Songjian Li, Yan Chen, Luqiao Luo. In situ-forming chitosan/nano -hydroxYAPatite/collagen gel for the delivery of bone marrow mesenchymal stem. Carbohydrate Polymers, 2011,85:21-267.( SCI, IF= 4.07)
[11] Xujie Liu#, Yan Chen#, Qianli Huang, Wei He, Qingling Feng*, Bo Yu*. A novel thermo-sensitive hydrogel based on thiolated chitosan/hydroxYAPatite/beta-glycerophosphate. Carbohydrate Polymers, 2014;110:62-69.（SCI, IF=4.07）
[12] Li X*, Liu H, Niu X, Yu B, Fan Y, Feng Q, Cui FZ, Watari F. The use of carbon nanotubes to induce osteogenic differentiation of human adipose-derived MSCs in vitro and ectopic bone formation in vivo.Biomaterials.2012, ,33(19),4783-4916（SCI,IF:8.5）