(1)基金项目
1.广州市科技计划2025年度农业和社会发展科技专题,重点项目,肥胖致下丘脑神经干细胞功能障碍促进衰老的机制研究,2026-1-1至2028年12-31,50万元,主持
2.国家自然科学基金委员会, 面上项目, 82470819, ETS1组蛋白乳酸化介导htNSCs失能在ACP致下丘脑损伤中的机制研究, 2025-01-01 至 2028-12-31, 48万元, 在研, 主持
3. 国家自然科学基金,青年项目,82103033,JAML负调控SIRT1激活小胶质细胞在颅咽管瘤下丘脑非可控炎症损伤的机制探究,30万元,在研,主持;
4. 广东省自然科学基金青年提升项目,2414070000044,DHCR24的介导星形胶质细胞脂质代谢障碍在ACP损伤下丘脑中的机制探究,2024/01-2026/12,30万元,在研,主持
5. 南方医科大学南方医院杰出青年培育计划,DGAT1介导脂毒性促进htNSCs衰老在肥胖相关认知障碍的机制研究,2024/01-2026/12,50万元,在研,主持
6、广州市科技计划项目,201707010149 ,经典WNT通路在恶性脑膜瘤血管生成拟态作用机制及靶向治疗研究,2017/5-2020/4,20万元,结题,主持
7、广东省自然科学基金博士启动项目,2016A030310377,经典wnt通路介导EMT在恶性脑膜瘤血管形成拟态作用及机制研究,2016/06-2019/06,10万元,结题,主持
8、 国家自然科学基金委员会, 面上项目, 81972352, 釉质性颅咽管瘤细胞通过AMPK-SREBP2通路过渡激活胆固醇代谢诱发小胶质细胞炎性反应的机制研究, 2020-01-01 至 2023-12-31, 55万元, 结题, 参与
9、国家自然科学基金委员会, 青年科学基金项目, 81802830, LncRNA AC092131.1 通过TPD52L2/Wnt/β-catenin调节胶质母细胞瘤EMT和复发的表观遗传学机制研究, 2019-01-01 至 2021-12-31, 21万元, 结题, 参与
10、国家自然科学基金委员会, 青年科学基金项目, 81801624, 肥大细胞通过组胺及其受体调控NMDA受体在神经精神性狼疮癫痫中的机制研究, 2019-01-01 至 2021-12-31, 21万元, 结题, 参与
(2)期刊论文
1.Zhang H, Wang C, Fan J, Chen Z, Yu H, Bai Y, Zhang T, Zhu Q, Feng Y, Niu P, Chen J, Yang L, Li X, Yu L, Qi S, Liu Y. A Patient-Derived Organoid Biobank of Adamantinomatous Craniopharyngioma as a Platform for Drug Discovery. Adv Sci (Weinh). 2025 Nov 18:e03924. doi: 10.1002/advs.202503924. Epub ahead of print. PMID: 41250940.
2.Yu H, Zhang T, Chen J, Li X, Zhang H, Guo R, Wu C, Zhang L, Fan J, Wang C, Qi S, Liu Y. Ceritinib inhibits growth and ACTH production of PitNETs: Insights from patient-derived organoids. Pharmacol Res. 2025 Nov;221:107993. doi: 10.1016/j.phrs.2025.107993. Epub 2025 Oct 11. PMID: 41083089.
3.Chen J, Zhang T, Wang C, Niu P, Huang L, Guo R, Wu C, Zhang H, Wu Z, Qi S, Liu Y. Therapeutic Potential of Growth Hormone in Peripheral Nerve Injury: Enhancing Schwann Cell Proliferation and Migration Through IGF-1R-AKT and ERK Signaling Pathways. Glia. 2025 Apr;73(4):805-821. doi: 10.1002/glia.24653. Epub 2024 Nov 28. PMID: 39610064.
4.Wang, C., Zhang, H., Guo, R., Cao, Y., Pan, J., Yu, H., … & Liu, Y. (2024). Establishment and characterisation of stam4, a novel human adamantinomatous craniopharyngioma cell line, through human telomerase reverse transcriptase ectopic expression‐mediated immortalisation. Neuropathology and Applied Neurobiology, 50(1). https://doi.org/10.1111/nan.12958
5.Zhang X, Chen C, Liu Y. Navigating the metabolic maze: anomalies in fatty acid and cholesterol processes in Alzheimer's astrocytes. Alzheimers Res Ther. 2024 Mar 23;16(1):63. doi: 10.1186/s13195-024-01430-x. PMID: 38521950; PMCID: PMC10960454.
6.Yang L, Liu Y, Wang C, Feng Z, Yu L, Pan J, Peng J, Nie J, Zhou M, Ou Y, Liu T, Qi S, Fan J. Distinction of papillary and adamantinomatous craniopharyngioma: Clinical features, surgical nuances and hypothalamic outcomes. Neoplasia. 2024 Oct 1;57:101060. doi: 10.1016/j.neo.2024.101060. Epub ahead of print. PMID: 39357265.
7.Wang C, Zhang H, Fan J, Li Q, Guo R, Pan J, Liu Y, Peng J, Zhu Q, Feng Y, Wu C, Luo P, Qiu X, Shi J, Deng Y, Qi S, Liu Y. Inhibition of integrated stress response protects against lipid-induced senescence in hypothalamic neural stem cells in adamantinomatous craniopharyngioma. Neuro Oncol. 2023 Apr 6;25(4):720-732. doi: 10.1093/neuonc/noac261. PMID: 36454228; PMCID: PMC10076952
8.Liu X, Zhang H, Wang C, Li Z, Zhu Q, Feng Y, Fan J, Qi S, Wu Z, Liu Y. Tumor-selective Blockade of CD47 Signaling with CD47 Antibody for Enhanced Anti-tumor Activity in Malignant Meningioma. Curr Neuropharmacol. 2023;21(10):2159-2173. doi: 10.2174/1570159X21666230511123157. PMID: 37171006.
9.Zhang, H., Wang, C., Fan, J., Guo, R., Zhu, Q., Pan, J., Peng, J., Wu, Z., Qi, S., & Liu, Y. (2023). Factor analysis and subtyping significance of CTNNB1 gene mutation detection in adamantinomatous craniopharyngioma. Genes & Diseases.
10.Zhang H, Wang C, Fan J, Zhu Q, Feng Y, Pan J, Peng J, Shi J, Qi S, Liu Y. CD47 Promotes the Proliferation and Migration of Adamantinomatous Craniopharyngioma Cells by Activating the MAPK/ERK Pathway, and CD47 Blockade Facilitates Microglia-mediated Phagocytosis. Neuropathol Appl Neurobiol. 2022 Feb 13:e12795. doi: 10.1111/nan.12795. Epub ahead of print. PMID: 35156226.
11.Liu Y, Wang CH, Fan J, Peng JX, Pan J, Zhang X, Qi ST. Establishing a papillary craniopharyngioma cell line by SV40LT-mediated immortalization. Pituitary. 2021 Apr;24(2):159-169. doi: 10.1007/s11102-020-01093-5. Epub 2020 Oct 12. PMID: 33044631.
12.Qi S, Liu Y, Wang C, Fan J, Pan J, Zhang X, Lu Y. Membrane Structures Between Craniopharyngioma and the Third Ventricle Floor Based on the QST Classification and Its Significance: A Pathological Study. J Neuropathol Exp Neurol. 2020 Sep 1;79(9):966-974. doi: 10.1093/jnen/nlaa087. PMID: 32791520.
13.Liu Y, Qi ST, Wang CH, Pan J, Fan J, Peng JX, Zhang X, Bao Y, Liu YW. Pathological Relationship Between Adamantinomatous Craniopharyngioma and Adjacent Structures Based on QST Classification. J Neuropathol Exp Neurol. 2018 Nov 1;77(11):1017-1023. doi: 10.1093/jnen/nly083. PMID: 30239800.
14.Yang L, Li K, Li W, Wang C, Liu Y, Zhang H, Pan J, Qi S, Peng J. Expression of Insulin-like Growth Factor Type 1 Receptor is Linked to Inflammation in Adamantinomatous Craniopharyngioma. Neuroendocrinology. 2021 Dec 13. doi: 10.1159/000521458. Epub ahead of print. PMID: 34915523.
15.Fan J, Liu Y, Pan J, Peng Y, Peng J, Bao Y, Nie J, Wang C, Qiu B, Qi S. Endoscopic endonasal versus transcranial surgery for primary resection of craniopharyngiomas based on a new QST classification system: a comparative series of 315 patients. J Neurosurg. 2021 Mar 5:1-12. doi: 10.3171/2020.7.JNS20257. Epub ahead of print. PMID: 33668037.
16.Wang CH, Qi ST, Fan J, Pan J, Peng JX, Nie J, Bao Y, Liu YW, Zhang X, Liu Y. Identification of tumor stem-like cells in admanatimomatous craniopharyngioma and determination of these cells' pathological significance. J Neurosurg. 2019 Aug 30:1-11. doi: 10.3171/2019.5.JNS19565. Epub ahead of print. PMID: 31470408.
(3)学术奖励
1、刘忆(4/9),膜性外科学概念的建立与应用,广东省,医学科技奖,一等奖,2023,(漆松涛,张喜安,包赟,刘忆,陆云涛,潘军,樊俊,汪潮湖,彭俊祥)
2、刘忆(3/10),颅咽管瘤可以治愈的临床及基础研究,教育部,高等学校科学研究优秀成果奖,二等奖,2018(漆松涛,潘军,刘忆,樊俊,包赟,彭俊祥,张喜安,陆云涛,汪潮湖,聂晶)
3、刘忆(7/10),基于膜性概念的神经外科手术理论和实践,广东省,科学技术进步奖,二等奖,2016(漆松涛,冯文峰,潘军,张喜安,樊俊,陆云涛,刘忆,龙浩,黄广龙,彭俊祥)
(4)专著
1、《Atlas of Craniopharyngioma:Pathology, Classification and Surgery》, Springer, 2020.1.1 (ISBN: 978-981-13-7322-0, 副主编)
2、《Craniopharyngiomas Classification and Surgical Treatment》, Bentham,2017.11.1 (ISSN: 2405-7401, 编者)
3、《颅咽管瘤漆松涛2020观点》,科学技术文献出版社,2019-10-1(ISBN:9787518960965,编者)
4、《颅咽管瘤》,人民卫生出版社,2018-5-1(ISBN:9787117264631,编者)
5、《显微神经外科图解及述评》 (第2版),人民卫生出版社,2018-5-1(ISBN:9787117265027,副主编)
6、《膜性概念神经外科学》,人民卫生出版社,2018-5-1(ISBN:9787117263986,编者)
7、《神经外科微创手术入路解剖图谱》,广东科技出版社,2018-1-1(ISBN:9787535968142,主编)
8、《颅咽管瘤2024观点》,科学技术文献出版社,2024-9-1(主编)
9、《现代颅底外科学-功能保存综合指南》,中国科学技术出版社,2024年(副主译)