1993.09-2000.07第一军医大学临床医学七年制本-硕连读;毕业后留校在南方医院内分泌代谢科工作至今,期间留学美国哈佛大学医学院Joslin糖尿病中心代谢&生理研究室。广东省杰出青年医学人才,岭南名医,广东省医师协会内分泌科医师分会副主任委员。研究方向包括糖尿病肾脏病的发病机制、内分泌性高血压与肾上腺疾病诊疗、肥胖及相关代谢性疾病防治等。先后获国家自然科学基金资助5项,发表SCI论文十余篇。
主要致力于糖尿病肾脏病的发病机制、肾上腺疾病与代谢等基础与临床研究
[1]. Long noncoding RNA XIST regulates brown preadipocytes differentiation and combats high-fat diet induced obesity by targeting C/EBPα. Mol Med, 2022 Jan 21; 28(1): 6.
[2]. Brown adipose tissue transplantation ameliorates diabetic nephropathy through the miR-30b pathway by targeting Runx1. Metabolism, 2021 Dec; 125: 154916.
[3]. Role of PDK4 in insulin signaling pathway in periadrenal adipose tissue of pheochromocytoma patients. Endocr-Relat Cancer. 2020 Oct; 27(10): 583-589.
[4]. MiR-455 Targeting SOCS3 Improve Liver Lipid Disorders in Diabetic Mice. Adipocyte, 2020 Apr; 9(1): 179-188.
[5]. Exendin-4 improves renal lipid deposit and fibrosis through AMPK pathway independent of brown adipose tissue activation. J Diabetes Res, 2020; 9084567.
[6].Transplantation of brown adipose tissue up-regulates miR-99a to ameliorates liver metabolic disorders in diabetic mice by targeting NOX4. Adipocyte, 2020; 9 (1): 57-67.
[7]. Increased oxidative stress, inflammation and fibrosis in perirenal adipose tissue of patients with cortisol-producing adenoma. Adipocyte, 2019; 8(1): 347-56.
[8]. Renoprotective effects of brown adipose tissue activation in diabetic mice. J Diabetes, 2019; 11(12): 958-970.
[10]. Metformin Improves Epithelial-to-Mesenchymal Transition Induced by TGF-β1 in Renal Tubular Epithelial NRK-52E Cells via Inhibiting Egr-1. J Diabetes Res, 2018 Jun 27;2018:1031367.
[11]. Inflammation and Fibrosis in Perirenal Adipose Tissue of Patients With Aldosterone-Producing Adenoma. Endocrinology, 2018;159(1):227-237.
[12]. High glucose down-regulates microRNA-181a-5p to increase pro-fibrotic gene expression by targeting early growth response factor 1 in HK-2 cells. Cell Signal, 2017; 31: 96-104.