医学博士，主任医师，教授，博士生导师，博士后合作导师，南方医科大学珠江医院康复医学科主任，南方医科大学康复医学院副院长。
国家自然科学基金与广东省自然科学基金项目评审专家，科技奖评审专家。
中华医学会物理医学与康复分会全国委员、康复评定学组副组长。
中国医师协会康复医师分会常务委员
中国康复医学会脑机接口康复分会副主任委员
中国康复医学会脑功能检测与调控分会常务委员
中国残联康复医学会康复评定专委会副主任委员
中国医疗保健国际交流促进会康复医学分会常务委员
广东省医学会物理医学与康复医学分会副主任委员
广东省医学会心身医学分会副主任委员
广东省医师协会康复医师分会常委
广东省康复医学会脑功能检测与调控分会会长。
主持国家自然科学基金面上项目4项及其它科研项目10余项。中国康复医学会科技进步一等奖1项，广东医学科技奖二等奖1项，中华医学会教育技术成果二等奖1项，省部级科技进步二等奖及教学成果二等奖各2项。发表国内外学术刊物论文103篇（SCI收录60篇），包括Nature Communications,BMC Medicine,Journal of Neuroinflammation等国际顶级期刊和专业顶尖期刊，总影响因子近300分，H指数18。主编医学视听教材3套，参编著作9本。授权专利8项。
科研课题：
1 PVN小胶质细胞-催产素神经元-脊髓背角轴在神经病理性疼痛中的作用及iTBS镇痛机制研究（2024.01-2027.12 ）国家自然科学基金项目 55万
2 sTREM2介导小胶质细胞-神经元“对话”在脉冲射频改善神经病理性疼痛中的机制研究 （2022.01~2025.12） 国家自然科学基金项目 55万
3 基于人格特质分层的“预期因素”在镇痛与致痛作用中的脑网络机制研究 （2018.01~2021.12） 国家自然科学基金项目 55万
4 痛觉超敏疼痛矩阵失衡及其针刺镇痛的再平衡机制研究 （2015.01~2018.12） 国家自然科学基金项目 66万
5 ChREBP通过HIF-1α介导小胶质细胞代谢重编程调控神经病理性疼痛的机制研究（2023.01-2025.12）广东省自然科学基金项目 10万
6 TREM2/FoxO3a介导的小胶质细胞自噬在白藜芦醇改善神经病理性疼痛中的作用和机制研究 （2021.01~2023.12） 广东省自然科学基金项目 10万
代表性文章（近五年）：
1 Modulation of glymphatic system by visual circuit activation alleviates memory impairment and apathy in a mouse model of Alzheimer’s disease，Nature Communications，2025，IF=14.7，中科院1区，第一作者
2 Multimodal Non-Invasive Non-Pharmacological Therapies for Chronic Pain: Mechanisms and Progress，BMC Medicine，2023，IF=9.3，中科院1区，末位通讯
3 Resveratrol Mediates Mechanical Allodynia Through Modulating Inflammatory Response via the TREM2-autophagy Axis in SNI Rat Model，Journal of Neuroinflammation，2020，IF=8.322，中科院1区，末位通讯
4 Relation Between Abnormal Spontaneous Brain Activity and Altered Neuromuscular Activation of Lumbar Paraspinal Muscles in Chronic Low Back Pain，Archives of Physical Medicine and Rehabilitation，2024，IF=3.6，中科院1区，共同通讯
5 ALKBH5 protects against stroke by reducing endoplasmic reticulum stress-dependent inflammation injury via the STAT5/PERK/EIF2α/CHOP signaling pathway in an m6A-YTHDF1-dependent manner，Experimental Neurology，2023，IF=5.3，中科院2区，末位通讯
6 AdipoRon Engages Microglia to Antinociception through the AdipoR1/AMPK Pathway in SNI Mice，Mediators of Inflammation，2023，IF=4.6，中科院3区，末位通讯
7 Editorial:Pain-related neural networks and regulation mechanisms.Frontiers in Molecular Neuroscience.（IF4.8）2022
8 Comorbid depressive symptoms can aggravate the functional changes of the pain matrix in patients with chronic back pain: A resting-state fMRI study. Frontiers in Aging Neuroscience.（IF4.8）2022
9 SNHG5/miR-299-5p/ATF2 Axis as a Biomarker in Immune Microenvironment of Intervertebral Disc Degeneration. Mediators of Inflammation.（IF4.6）2022
10 LANCL1 as the Key Immune Marker in Neuropathic Pain.Neural Plasticity.（IF3.1）2022
11 Analysis of Correlation BetweenWhite Matter Changes and Functional Responses in Post-stroke Depression. Frontiers in aging neuroscience. （IF:5.75）2021,10
12 Brain Network to Placebo and Nocebo Responses in Acute Experimental Lower Back Pain: A Multivariate Granger Causality Analysis of fMRI Data. Frontiers in Behavioral Neuroscience. （IF:3.558）2021,09
13 The Inhibitory Effect of Emotional Conflict Control on Memory Retrieval. Neuroscience. （IF:3.59）2021,08
14 Sex Differences in the Blood Oxygen Level-Dependent Signal to Placebo Analgesia and Nocebo Hyperalgesia in Experimental Pain: A Functional MRI Study. Frontiers in Behavioral Neuroscience. （IF:3.558）2021,08
15 Personality differences in brain network mechanisms for placebo analgesia and nocebo hyperalgesia in experimental pain: a functional magnetic resonance imaging study Annals of Translational Medicine. （IF:3.93） 2021,04
16 Personality Differences of Brain Networks in Placebo Analgesia and Nocebo Hyperalgesia: A Psychophysiological Interaction (PPI) Approach in fMRI. NEURAL PLASTICITY. （IF:3.599） 2020,10
17 Performance of healthy persons under pain in different cognitive load tasks: An event‐related potential study on experimental pain individuals. Brain and Behavior. （IF:2.708）2020,10
18 Changes in Empathy in Patients with Chronic Low Back Pain: A Structural-Functional Magnetic Resonance Imaging Study. Frontiers in Human Neuroscience. （IF:3.169）2020,9
19 Upregulation of Mlxipl induced by cJun in the spinal dorsal horn after peripheral nerve injury counteracts mechanical allodynia by inhibiting neuroinflammation. Aging. （IF:5.6）2020,12
20 Reduction of Silent Information Regulator 1 Activates Interleukin-33/ST2 Signaling and Contributes to Neuropathic Pain Induced by Spared Nerve Injury in Rats. Frontiers in Molecular Neuroscience. （IF:5.639）2020,11
21自发性知觉经络反应的脑电频谱特征研究. 中华神经医学杂志. 2020,11
22 Investigation of the emotional network in depression after stroke: A study of multivariate Granger causality analysis of fMRI data. Journal of affective disorders. （IF:4.839）2019,10
23 Altered functional connectivity of amygdala with the fronto-limbic-striatal circuit in temporal lobe lesion as a proposed mechanism for post-stroke depression. American Journal of Physical Medicine & Rehabilitation. （IF:2.159） 2019,11
24 Brain pathways of pain empathy activated by pained facial expressions: a meta-analysis of fMRI using the activation likelihood estimation method. Neural Regeneration Research. （IF:5.135）2019,11
25 Physical exercise promotes proliferation and differentiation of endogenous neural stem cells via ERK in rats with cerebral infarction. Molecular Medicine Reports. （IF:2.952） 2018,18
26 功能性磁共振研究针刺镇痛机制的系统评价. 中国中医基础医学杂志. 2018,1