基本情况： 王来友，男，1977年12月生。

        现任广东省人民医院临床药学科副主任（主持工作），教授（研究员）; 英语、法语优秀，世界卫生组织任职后备人才（卫健委）。广东省南山医药创新研究院特聘研究员。

        2006 年毕业于中山大学临床药理研究所，获医学博士学位。2004/06-2005/12、2009/03-2010/07、2014/04-2015/04期间先后在法国Franche-Comté大学、美国Kansas University医学中心、澳大利亚Griffith大学学习与工作。 

        国内外主要学术兼职：广东省药理学会药品再评价专业委员会主任委员、中华医学会广东省临床药学分会青年专委会副主任委员、广东省药理学会中药药理专委会副主任委员、中国药学会循证药学专业委员会委员等；国家自然科学基金评审专家；《Pharmacogenomics》、《Drug metabolism and Disposition》等SCI杂志审稿人。

         主要科研业绩：至今共承担各级科研基金十余项，包括：国家自然科学基金面上项目3项、国家自然科学青年基金项目1项、广东省自然科学基金面上项目2项、教育部留学回国人员科研启动基金项目、国家公派出国留学广东省地方合作项目等；发表科研论文75篇，其中SCI收录40余篇，第一和通讯作者26篇，包括Nature Medicine、Drug metabolism and Disposition、Pharmacogenomics、Marine Drugs、RSC advances等，获得中国发明授权专利五项。参编《循证药学》等学术专著、高等院校教材3部。培养研究生二十余人。

      主要荣誉：广东省科技技术进步一等奖2项。

目前主要研究方向：临床药理学、中药学、真实世界研究、生物药剂学

1. Tiancheng Gu#,Wei Liu#,Laiyou Wang*,Jisheng Cheng*. UPLC-Q-TOF-MS analysis of chemical constituents of the Kadsura coccinea extract with effect of attenuating lipid accumulation in vitro. Natural Product Communications. 2024, April 19(4):1-12.
2. Yue Li, Ting Li, Hengjie Su, Xin Zhang, Jiangbo Pu, Hong Sun,Qiong Liu, Bowen Zhang, Biao Sun, Jia Li, Xinxin Yan, Laiyou Wang. A multi-center big-data approach for precise PICC-RVT prognosis and identification of major risk factors in clinical practice. Heliyon 10 (2024) e39178.
3. Weiran Pang, Bowen Zhu, Honghui Li, Yingying Zhou, Chi Man Woo, Xiazi Huang,Tianting Zhong, Hsuan Lo, Laiyou Wang, Puxiang Lai, and Liming Nie. Direct Monitoring of Whole-Brain Electrodynamics via High-Spatiotemporal-Resolution Photoacoustics with Voltage-Sensitive Dye. Laser Photonics Rev. 23 May 2024, 2400165.
4. Qin Huang , Meng-Jiao Hao , Lai-You Wang , Feng Wu , Hou-Jin Li , Jie Yuan , Jun Xu , Taifo Mahmud , Wen-Jian Lan, Isolation and stereospecific synthesis of indole alkaloids with lipid-lowering effects from the marine-derived fungus Colletotrichum gloeosporioides BB4. Phytochemistry,  2023, May 209（113612）:1-11.
5.  Yasi Zhou, Xiao Xiao, Chuyin Peng, Deli Song, Fan Ouyang, Laiyou Wang. Progesterone induces glioblastoma cell apoptosis by coactivating extrinsic and intrinsic apoptotic pathways. Molecular & Cellular Toxicology, 2023 Jan.
6. Si Chen, Ying Wang, Xiao Yuan and Laiyou Wang*. Total Synthesis Of C-8 Hydroxyl Substituted Lomefloxacin As the Photolysis Impurity. Letters In Organic Chemistry. 2022, 19(6): 484-489.
7. Yang H, Liang J, Lin C, Zhu Y, Yan J, Zhang W, Pang J, Yang W*, Yang F*, Wang L*. Effect of Dihydropyridine Enrichment in the Microstructure of the Palisade Layer on the Stability of Fat Nano-emulsions. Journal of pharmaceutical sciences . 2021 Jul 23:S0022-3549(21)00369-5. doi: 10.1016/j.xphs.2021.07.013. Online ahead of print.
8. Nan Lyu, Kai Wang, Fan Zhang, Haimei Qin, Yi Zhao, Ruibo Wu, Yubing Si*, Laiyou Wang*. Recognition of PDL1/L2 by different induced-fit mechanisms of PD1: a comparative study of molecular dynamics simulations. Phys. Chem. Chem. Phys., 2020 Jan 21; 22(3):1276-1287. PMID:31850422
9. Yuan F, Liang X, Chen X, Qin X, Tan C, Wang L.CYP2C19 is involved in the effect of Wuzhi tablet (Schisandra sphenanthera extract) and its constituents on the pharmacokinetics of intravenous voriconazole. Pharmazie. 2020 Nov 1;75(11):559-564. doi: 10.1691/ph.2020.0635. PMID：33239129
10. Yanying Kong, Qiuju Peng, Nan Lv, Jin Yuan, Zhirong Deng, Xiaolin Liang, Si Chen, Laiyou Wang*. Paeoniflorin exerts neuroprotective effects in a transgenic mouse model of Alzheimer’s disease via activation of adenosine A1 receptor. Neurosci Lett., 2020 Jun 21; 730:135016. PMID:32371159