毒理学系主任，教授，博士研究生导师。
长期致力于环境污染物的器官毒性及发育毒性机制研究。先后主持国家自然科学基金3项、省部级科研项目4项及广州市科技菁英“领航”项目 1 项。近3年，受邀担任国家自然科学基金及广东、浙江、湖南等多省市自然科学基金通讯评审专家；并长期担任 ACS Nano、Acta Pharm Sin B.、Gut Microbes、Advanced Science等国际权威高影响力 SCI 期刊的特约审稿专家。担任中国毒理学会第二届青年委员会常务委员、中国环境诱变剂学会第二届生物标志物专业委员会常务委员、广东省毒理学会第三届理事会常务理事。
近3年以通讯作者发表的代表性论文：
1. Chen L, Zhang K, Liu J, Li X, Liu Y, Ma H, Yang J, Li J, Chen L, Hsu C, Zeng J, Xie X*, Wang Q*. The role of the microbiotaegutebrain axis in methamphetamine-induced neurotoxicity: Disruption of microbial composition and short-chain fatty acid metabolism. Acta Pharmaceutica Sinica B. 2024. 14(11): 4832-4857.. (IF=14.8 小类I区)
2. Zhang K, Chen L, Yang J, Liu J, Li J, Liu Y, Li X, Chen L, Hsu C, Zeng J, Xie X*, Wang Q*. Gut microbiota-derived short-chain fatty acids ameliorate methamphetamine-induced depression- and anxiety-like behaviors in a Sigmar-1 receptor-dependent manner. Acta Pharmaceutica Sinica B. 2023. 13(12): 4801-4822. (IF=14.5 小类I区)
3. Zhang K, Yang J, Chen L, He J, Qu D, Zhang Z, Liu Y, Li X, Liu J, Li J, Xie X*, Wang Q*. Gut Microbiota Participates in Polystyrene Microplastics-Induced Hepatic Injuries by Modulating the Gut-Liver Axis. ACS Nano. 2023. 17(15): 15125-15145. (IF=17.1 小类I区)
4. Li JH, Liu JL, Li XW, Yang JZ, Liu Y, Wang H, Chen LJ, Zhang KK, Xie XL*, Wang Q*. Gut microbiota mediates prenatal METH exposure-induced anxiety- and depression-like behaviors by modulating the Wnt signaling pathway. Brain Behav Immun. 2025. 130: 106112. (IF=7.6 小类I区)
5. Chen YK, Lai MQ, Zhang QY, Zhong MT, Zhang JJ, Chen YQ, Guo XF, Wang Q, Xie XL*. Inulin alleviates intestinal changes caused by gestational PFOA and GenX exposure in the offspring of mice through reshaping maternal gut microbiota and vertically inhibiting the TLR4/NF-κB/NLRP3 inflammatory pathway in the pups. Environ Pollut. 2025. 382: 126749.(IF=7.3 小类II区)