代表论文:
Li, Z., Li, X., Lin, J., Wang, Y., Cao, H.*, Zhou, J.* (2024). Reevaluation by the CRISPR/Cas9 knockout approach revealed that multiple pluripotency-associated lncRNAs are dispensable for pluripotency maintenance while Snora73a/b is essential for pluripotency exit. Science China Life Sciences, 1-15.
Lin, Y.#, Zhang, Y.#, Sun, H., Jiang, H., Zhao, X., Teng, X., Lin, J., Shu, B., Sun, H., Liao, Y.*, Zhou, J.* (2024). NanoDeep: a deep learning framework for nanopore adaptive sampling on microbial sequencing. Briefings in Bioinformatics, bbad499.
Zhang, Y.#, Shi, Y.#, Lin, J., Li, X., Bin, Y.*, Zhou, J.* (2021). Immune cell infiltration analysis demonstrates excessive mast cell activation in psoriasis. Frontiers in Immunology, 4941.
Huang, H.#, Hu, Y.#, Huang, G., Ma, S., Feng, J., Wang, D., Lin, Y.*, Zhou, J.* and Rong, Z.* (2021) Tag-seq: a convenient and scalable method for genome-wide specificity assessment of CRISPR/Cas nucleases. Communications biology, 4(1), pp.1-8.
Li, X.#, Lin, J., Hu, Y., Zhou J.* (2020) PARMAP: A Pan-Genome-Based Computational Framework for Predicting Antimicrobial Resistance. Frontiers in microbiology 11.
Zhou, J.#, So, K.K.#, Li, Y.#, Yuan, J., Ding, Y, Chen, F., Huang, Y., Sun, H.* , and Wang, H.* (2019) Elevated H3K27ac in aged skeletal muscle tissue drives a fibrogenic conversion of muscle satellite cells. Aging cell, 18(5), e12996.
Zhao, Y.#, Zhou, J.#, He, L., Sun, H.* , Wang, H.* (2019) MyoD induced enhancer RNA interacts with hnRNPL protein via CAAA motif to activate target gene transcription during myogenic differentiation. Nature Communications, 10(1) (2019): 1-17.
Zhou, J.#, Huang, Y., Ding, Y., Yuan, J., Wang, H.* , Sun, H.* (2018). lncFunTK: A toolkit for functional annotation of long noncoding RNAs. Bioinformatics, 1, p2.
Zhou, J.#, Zhang, S.#, Wang, H.* , and Sun, H.* (2017). LncFunNet: an integrated computational framework for identification of functional long noncoding RNAs in mouse skeletal muscle cells. Nucleic Acids Res 45, e108–e108.
在研课题:
1. 老年人群新发传染病精准防治新技术与新策略转化应用研究(子课题2),参与,60万,2023-2026;
2. 新、突发重大传染病病原体发现、溯源及智能预警预测系统研发,参与,400万,2022-2024;
3. 衰老过程中增强子调控细胞外基质(ECM)重塑影响表皮干细胞稳态的分子机制研究,主持,58万,2021-2024;
4. RNA结合蛋白介导长链非编码RNA亚细胞定位的机制研究,主持,25万,2020-2022;
5. 南方医科大学皮肤病医院人才启动基金,主持,50万,2019-2023;