张先荣，三级教授，博士生导师，广东省高等学校骨与软骨再生医学重点实验室和国际华人骨研究学会联合研究中心负责人，国际华人骨研学会终身会员、中国医师协会骨科医师分会第五届委员会骨科基础学组委员、中国医师协会骨科医师分会青年委员会骨科基础学组委员、中华医学会骨科学分会第十一届青年委员会基础学组委员。2005年博士毕业于武汉大学生命科学学院，2009年至2012年宾夕法尼亚大学医学院骨外科博士后。主要研究方向为骨感染病程进展机制及防御策略、骨退行病变的机制及干预策略研究。近三年来以通讯作者在Nat Commun, Redox Biol, Mol Ther, PLoS Pathog等发表SCI论文9篇，授权国家发明专利2项。主持了国家自然科学基金6项(在研2项)。曾获美国骨研究学会“青年研究者奖”、Harold M. Frost“青年研究者奖”和Webster Jee“青年研究者奖”，国际华人骨研究学会“青年研究者奖”和“旅行奖”等。
1. Yang B, Su J, Wu J, Wang Z, Hu J, Yang M, Lin Y, Jin M, Bai X, Yu B, Zhang X*. Macrophage-derived amphiregulin induces myofibroblast transition in adipogenic lineage precursors near Staphylococcus aureus abscess in bone marrow. Nat Commun 2025, 16: 8409. (IF: 15.7)
2. Su J, Ma S, Yang M, Wu J, Chen Y, Jin M, Shi Q, Zhang X*. The protective role of adipogenic lineage precursors in maintaining bone marrow redox homeostasis in a mouse model of prenatal dexamethasone exposure. Redox Biol 2025, 86: 103820. (IF: 11.9)
3. Li K, Chen Y, Lin Y, Zhang G, Su J, Wu X, Cheng C, Wang Y, Yu B*, Zhang X*. PD-1/PD-L1 blockade is a potent adjuvant in treatment of Staphylococcus aureus osteomyelitis in mice. Mol Ther 2023, 31: 174-192. (IF: 12.0)
4. Yang B, Shu W, Hu J, Wang Z, Wu J, Su J, Tan J, Yu B*, Zhang X*. Aberrant Expression of SLC7A11 Impairs the Antimicrobial Activities of Macrophages in Staphylococcus Aureus Osteomyelitis in Mice. Int J Biol Sci 2024, 20: 2555-2575. (IF: 10.0)
5. Xie Y, Su J, Yang M, Liu Z, Chen T, Qian J, Yu B, Zhang X*. Prenatal dexamethasone exposure reduces osteoprogenitor proliferation in mice via histone modifications at the Mkp-1 gene locus. Commun Biol 2024, 7: 1589. (IF: 5.2, JCR小类一区)
6. Lin Y, Yang M, Cheng C, Wu J, Yu B, Zhang X*. Age-related dysregulation of CXCL9/10 in monocytes is linked to impaired innate immune responses in a mouse model of Staphylococcus aureus osteomyelitis. Cell Mol Life Sci 2024, 81: 300. (IF: 6.2)
7. Jin M, Wu X, Hu J, Chen Y, Yang B, Cheng C, Yang M, Zhang X*. EGFR-MEK1/2 cascade negatively regulates bactericidal function of bone marrow macrophages in mice with Staphylococcus aureus osteomyelitis. PLoS Pathog 2024, 20: e1012437. (IF: 4.9, JCR小类一区)
8. Cheng C, Deng M, Cheng C, Wu H, Wang Y, Lu M, Yao Z, Li K, Zhang X*, Yu B*. FOXO1-mTOR pathway in vascular pericyte regulates the formation of type H vessels to control bone metabolism. J Orthop Translat 2024, 49: 246-263. (IF: 7.8, , JCR小类一区)
9. Lu M, He R, Li C, Liu Z, Chen Y, Yang B, Zhang X*, Yu B*. Apolipoprotein E deficiency potentiates macrophage against Staphylococcus aureus in mice with osteomyelitis via regulating cholesterol metabolism. Front Cell Infect Microbiol 2023, 13:1187543. (IF: 4.8)