南方医科大学免疫学教授、博士生导师；主要研究炎症性疾病的天然免疫调控机制，聚焦于模式识别受体活化和功能的调控机制、关注肝肠等组织天然免疫稳态对疾病发生发展的影响；主持国家自然科学基金6项、省市级科研课题6项；近5年，以“通讯作者”在Journal of Hepatology、Nature Communications和Protein & Cell等杂志发表SCI论文20余篇。
Dong L, Xie J, Wang Y, Jiang H, Chen K, Li D, Wang J, Liu Y, He J, Zhou J, Zhang L, Lu X, Zou X, Wang XY, Wang Q*, Chen Z*, Zuo D*. Mannose ameliorates experimental colitis by protecting intestinal barrier integrity. Nat Commun. 2022, 13(1):4804. (*通讯作者)
Zuo D*, Chen Y, Cai JP, Yuan HY, Wu JQ, Yin Y, Xie JW, Lin JM, Luo J, Feng Y, Ge LJ, Zhou J, Cuinn JR, Zhao SJ, Tong X, Jin DY, Yuan S*, Dai SX*, Xu M*. A hnRNPA2B1 agonist effectively inhibits HBV and SARS-CoV-2 Omicron in vivo. Protein Cell. 2022. Epub ahead of print. (*通讯作者)
Tang Y, Li H, Li J, Liu Y, Li Y, Zhou J, Zhou Jia, Lu X, Zhao W, Hou J, Wang XY, Chen Z*, Zuo D*. Macrophage scavenger receptor 1 contributes to pathogenesis of fulminant hepatitis via neutrophil mediated complement activation. J Hepatol. 2018, 68(4):733-743 (*通讯作者)
Dong L, Jiang H, Chen K, Xie J, An Q, Deng F, Sun Z, Liu Y, Zhou J, Zhang L, Lu X, Wang M, Chen Z*, Zou X*, Zuo D*. Mannan-Binding Lectin Deficiency Limits Inflammation-induced Myeloid-Derived Suppressor Cells Expansion via Modulating Tumor Necrosis Factor Alpha-triggered Apoptosis. Int J Biol Sci. 2022, 18(4):1580-1593. (*通讯作者)
Luo J, Li L, Chang B, Zhu Z, Deng F, Hu M, Yu Y, Lu X, Chen Z, Zuo D*, Zhou J*. Mannan-Binding Lectin via Interaction With Cell Surface Calreticulin Promotes Senescence of Activated Hepatic Stellate Cells to Limit Liver Fibrosis Progression. Cell Mol Gastroenterol Hepatol. 2022, 14(1):75-99. (*通讯作者)
Liu Y, Xie X, Wang P, Luo J, Chen Y, Xu Q, Zhou J, Lu X, Zhao J*, Chen Z*, Zuo D*. Mannan-Binding Lectin Reduces Epithelial-Mesenchymal Transition in Pulmonary Fibrosis via Inactivating the Store-Operated Calcium Entry Machinery. J Innate Immun, 2022, 7: 1-13. (*通讯作者)
Xie M, Yin Y, Chen L, Yin A, Liu Y, Liu Y, Dong L, Lai Q, Zhou J, Zhang L, Xu M, Chen Z, Zuo D*. Scavenger receptor A impairs interferon response to HBV infection by limiting TRAF3 ubiquitination through recruiting OTUB1. FEBS J. 2020, 287(2): 310-324 (*通讯作者)
Li H, Liu Y, Li J, Liu Y, Dong L, Yin Y, Yu Y, Zhou J, Zhang L, Lu X, Chen Z*, Zuo D*. Mannan-binding lectin attenuates acetaminophen-induced hepatotoxicity by regulating CYP2E1 expression via ROS-dependent JNK/SP1 pathway. Eur J Immunol. 2019, 49(4):564-575. (*通讯作者)（封面文章）
Li J, Li H, Yu Y, Liu Y, Liu Y, Ma Q, Zhang L, Lu X, Wang XY, Chen Z*, Zuo D*, Zhou J*. Mannan-binding lectin suppresses growth of hepatocellular carcinoma by regulating hepatic stellate cell activation via the ERK/COX-2/PGE2 pathway. Oncoimmunology. 2018, 8(2):e1527650. (*通讯作者)
Zhao N, Wu J, Xiong S, Zhang L, Lu X, Chen S, Wu Q, Wang H, Liu Y, Chen Z*, Zuo D*. Mannan-binding lectin, a serum collectin, suppresses T-cell proliferation via direct interaction with cell surface calreticulin and inhibition of proximal T-cell receptor signaling. FASEB J. 2017, 31(6):2405-2417. (*通讯作者)