获奖成果:
2022入榜《广东省第二届实力中青年医生》
2022被评为阳春市第七批市管拔尖人才
2018年被评为广东省杰出青年医学人才
2018受聘为人民日报《健康时报 》“足部科学研究院”专家顾问
2018年受聘为羊城晚报岭南名医智库特邀专家
2017年入榜首届《胡润.平安中国好医生榜》
2017年首届南粤好医生暨第三届羊城好医生评选活动荣获“羊城好医生”称号
2016年在“敬佑生命·2016荣耀医者”公益评选中荣获“金柳叶刀奖”
2014年鲁甸地震抗震救灾荣获“国家卫生应急先进个人”荣誉称号
2014年1月24日完成世界首例采用3D打印技术微创腹腔镜辅助下髋臼骨折内固定术,CCTV1、CCTV13、CCTV4、本港台、广东新闻联播等多家电视台及网站、报纸广泛报道
2010年玉树地震抗震救灾荣获“广东青年五四奖章集体”“全国抗震救灾英雄集体”荣誉称号
最具代表性论文(按时间倒序排序):
1. Guo H, Yan H, Yan H, Liu Y, Zeng C.Comparison of Arthroscopic Microfracture for Osteochondral Lesions of the Talus With and Without Small and Shallow Subchondral Cysts. Foot Ankle Int. 2024 Mar 6:10711007241227936. doi: 10.1177/10711007241227936. Online ahead of print.PMID: 38445607
2. Wei Y, Pan H, Yang J, Zeng C, Wan W, Chen S.Aligned cryogel fibers incorporated 3D printed scaffold effectively facilitates bone regeneration by enhancing cell recruitment and function.Sci Adv. 2024 Feb 9;10(6):eadk6722. doi: 10.1126/sciadv.adk6722. Epub 2024 Feb 7.PMID: 38324693
3. Wei Y, Guo H, Chen Z, Sun N, Zeng C.Autologous Costal Chondral/Osteochondral Transplantation and Costa-Derived Chondrocyte Implantation for Articular Cartilage Repair: Basic Science and Clinical Applications.Orthop Surg.2024 Mar;16(3):523-531.doi:10.1111/os.13992. Epub 2024 Jan 25.PMID: 38272834.PMCID: PMC10925498
4. Pan H, Wei Y, Zeng C, Yang G, Dong C, Wan W, Chen S.
Hierarchically Assembled Nanofiber Scaffold Guides Long Bone Regeneration by Promoting Osteogenic/Chondrogenic Differentiation of Endogenous Mesenchymal Stem Cells.Small. 2024 Jan 23:e2309868. doi: 10.1002/smll.202309868. Online ahead of print.PMID: 38259052
5. Jiang F, Guo H, Zeng Q, Long P, Zeng C, Yan H.Preoperative temporary fixation for fractures around the ankle using a simple extensible external fixator significantly improves patient comfort. Foot Ankle Surg. 2023 Dec 13:S1268-7731(23)00220-5. doi: 10.1016/j.fas.2023.12.001. Online ahead of print.PMID: 38123374
6. Wei Y, Guo H, Sun N, Tang Z, Ding J, Zeng C.Autologous Costal Osteochondral Transplantation for Cystic Osteochondral Lesions of the Talus: Feasible and Effective.Orthop Surg. 2023 Aug 30. doi: 10.1111/os.13864. Online ahead of print.PMID: 37649305
7. Shen S, Si M, Zeng C, Liu EK, Chen Y, Vacher J, Zhao H, Mohan S, Xing W.Leucine Repeat Rich Kinase 1 Controls Osteoclast Activity by Managing Lysosomal Trafficking and Secretion.Biology (Basel). 2023 Mar 29;12(4):511. doi: 10.3390/biology12040511.PMID: 37106712
8. Sun N, Liu Y, Yan H, Zhang Z, Li Y, Zeng C.Recent Progress in the Classification and Operation of Sacral Fractures.Emerg Med Int. 2023 Mar12;2023:2795722.doi:10.1155/2023/2795722. eCollection 2023.PMID: 36950069
9. Lu H, Liu Y, Xie W, Liang H, Guo H, Quan Y, Zhang B, Zeng C, Xu H.The Reliability and Accuracy of the Medial Malleolar Fracture Classification Based on 3D CT Reconstruction.Orthop Surg. 2023 Jul;15(7):1790-1798. doi: 10.1111/os.13754. Epub 2023 Jun 1.PMID: 3725997
10. Sun N, Chen J, Chen Z, Zeng C, Guo H.Clinical Outcomes of Fusion in Type II Accessory Naviculars With or Without Asymptomatic Flatfeet.Foot Ankle Int. 2023 Feb;44(2):139-147. doi: 10.1177/10711007221140847. Epub 2022 Dec 23.PMID: 36564915.
11. Guo H, Chen B, Chen Z, Sun N, Ji G, Zeng C. The lasso-loop technique is equivalent to the simple suture technique in arthroscopic anterior talofibular ligament repair. Knee Surg Sports Traumatol Arthrosc. 2022 Dec 14. doi: 10.1007/s00167-022-07283-x. Epub ahead of print. PMID: 36515734.
12. Guo H, Chen Z, Wei Y, Chen B, Sun N, Liu Y, Zeng C.Autologous Osteoperiosteal Transplantation for the Treatment of Large Cystic Talar Osteochondral Lesions.Orthop Surg. 2023 Jan;15(1):103-110. doi: 10.1111/os.13586. Epub 2022 Nov 15.PMID: 36380533
13. Tan X, Zeng C, Li H, Tan Y, Zhu H.Circ0038632 modulates MiR-186/DNMT3A axis to promote proliferation and metastasis in osteosarcoma.Front Oncol. 2022 Aug 18;12:939994. doi: 10.3389/fonc.2022.939994. eCollection 2022.PMID: 36059626
14. Huang S, Wang X, Zhang M, Huang M, Yan Y, Chen Y, Zhang Y, Xu J, Bu L, Fan R, Tang *H, Zeng C, Zhang L, Zhang L.Activin B-activated Cdc42 signaling plays a key role in regulating adipose-derived mesenchymal stem cells-mediated skin wound healing.Stem Cell Res Ther. 2022 Jun 11;13(1):248. doi: 10.1186/s13287-022-02918-9.
15. Guo H, Zeng C.Technique Tip: Correcting Malalignment of the Talus Using a Pin-Based Distracter During Arthroscopic Ankle Arthrodesis.J Foot Ankle Surg. 2022 Mar-Apr;61(2):434-437. doi: 10.1053/j.jfas.2021.02.018. Epub 2021 Nov 16.PMID: 34896009
16. Huang J, Guo H, Huang W, Tan X, Huang H, Zeng C. Topical Application of Tranexamic Acid Can Reduce Postoperative Blood Loss in Calcaneal Fractures: A Randomized Controlled Trial. J Foot Ankle Surg. 2022 Jan 23;S1067-2516(22)00020-5. doi: 10.1053/j.jfas.2022.01.017.
17. Huang H, Zhang P, Xiang C, Zeng C, Du Q, Huang W.Effect of bone marrow mesenchymal stem cell transplantation combined with lugua polypeptide injection on osteoarthritis in rabbit knee joint. Connect Tissue Res. 2022 Jul;63(4):370-381. doi: 10.1080/03008207.2021.1962314. Epub 2021 Aug 6.PMID: 34355626.
18. 颜浩瀚,林羲疆,卫愉轩,郭浩,孙念,张志强,李严兵,曾参军. Lisfranc损伤足底入路的解剖学研究及初步疗效分析[J]. 中华创伤骨科杂志,2022,24(4):316-322. DOI:10.3760/cma.j.cn115530-20220210-00083.
19. Zhu, G., Zeng, C., Yuan, S., & Li, R. (2021). Emergency amputation necessitated within 24 hours by a human bite: a case report. Journal of International Medical Research, 49(5), 030006052110122. DOI:10.1177/03000605211012201
20. 林羲疆,李严兵,黄华军,郭浩,温志深,陈博韬,周奇,陈柱宏,曾参军.改良腹直肌旁切口入路前路钢板固定骶骨骨折的解剖学研究[J]. 中华创伤骨科杂志,2021,23(11):969-974. DOI:10.3760/cma.j.cn115530-20210111-00013.
21. Lin Y, Chen T, Chen J, Fang Y, Zeng C.Endogenous Aβ induces osteoporosis through an mTOR-dependent inhibition of autophagy in bone marrow mesenchymal stem cells (BMSCs).Ann Transl Med. 2021 Dec;9(24):1794. doi: 10.21037/atm-21-6427.
22. Li R, Zeng C, Yuan S, Chen Y, Zhao S, Ren GH.Free flap transplantation combined with Ilizarov bone transport for the treatment of severe composite tibial and soft tissue defects.J Int Med Res. 2021 May;49(5):3000605211017618. doi: 10.1177/03000605211017618.
23. Zhu G, Zeng C, Qian Y, Yuan S, Ye Z, Zhao S, Li R. Tensile strain promotes osteogenic differentiation of bone marrow mesenchymal stem cells through upregulating lncRNA-MEG3. Histol Histopathol. 2021 Sep;36(9):939-946. DOI: 10.14670/HH-18-365.
24. Huang H, Xing W, Zeng C, Huang W.Pararectus approach combined with three-dimensional printing for anterior plate fixation of sacral fractures.Injury. 2021 Oct;52(10):2719-2724. doi: 10.1016/j.injury.2020.03.049. Epub 2020 May 1.
25. Li RG, Zeng CJ, Yuan S, Hu JJ, Zhang P, Chen YB, Zhao SW, Ren GH. Reconstruction of Large Area of Deep Wound in the Foot and Ankle with Chimeric Anterolateral Thigh Perforator Flap. Orthop Surg. 2021 Jul;13(5):1609-1617. DOI: 10.1111/os.13046.
26. Qiu Y, Zhu G, Zeng C, Yuan S, Qian Y, Ye Z, Zhao S, Li R.Nextgeneration sequencing of miRNAs and lncRNAs from rat femur and tibia under mechanical stress.Mol Med Rep. 2021 Aug;24(2):561. doi: 10.3892/mmr.2021.12200. Epub 2021 Jun 10.
27. Huang, Jihui; Xie, Fengjiao; Tan, Xinyu; Xing, Weirong; Zheng, Yushi; Zeng, Canjun (2020). Treatment of Osteosarcoma of the Talus with a 3D-Printed Talar Prosthesis. The Journal of Foot and Ankle Surgery, DOI:10.1053/j.jfas.2020.01.012
28. Ye Z, Zhao S, Zeng C, Luo Z, Yuan S, Li R. Study on the relationship between the timing of conversion from external fixation to internal fixation and infection in the treatment of open fractures of extremities. J Orthop Surg Res. 2021 Nov 7;16(1):662. DOI: 10.1186/s13018-021-02814-7.
29. Zhao S, Zeng C, Yuan S, Li R. Reconstruction of coronoid process of the ulna: a literature review. J Int Med Res. 2021 Apr;49(4):3000605211008323. DOI: 10.1177/03000605211008323.
30. Guo, Hao; Huang, Wei-Qi; Lin, Xi-Jiang; Chen, Bo-Tao; Zeng, Can-Jun (2020). Validation of a Chinese translation of the identification of functional ankle instability questionnaire. Chinese Medical Journal, 133(18), 2261–2262. DOI:10.1097/cm9.0000000000001020
31. Guo, Hao; Huang, Weiqi; Zeng, Canjun (2020). Ankle Fracture with a Complex Injury Mechanism and Misleading Hook Test Result: A Case Report. The Journal of Foot and Ankle Surgery, 59(6), 1275–1278. DOI:10.1053/j.jfas.2019.10.014
32. Ji-Hui Huang, Hui Liao , Xin-Yu Tan , Wei-Rong Xing, Qi Zhou, Yu-Shi Zheng , Hong-Yu Cao, Can-Jun Zeng. Surgical treatment for both-column acetabular fractures using pre-operative virtual simulation and three-dimensional printing techniques.Chinese Medical Journal.2020.395-401
33. Zhu X, Zhao Z, Zeng C, Chen B, Huang H, Chen Y, Zhou Q, Yang L, Lv J, Zhang J, Pan D, Shen J, Duque G, Cai D.HNGF6A Inhibits Oxidative Stress-Induced MC3T3-E1 Cell Apoptosis and Osteoblast Phenotype Inhibition by Targeting Circ_0001843/miR-214 Pathway.Calcif Tissue Int. 2020 May;106(5):518-532. doi: 10.1007/s00223-020-00660-z. Epub 2020 Mar 18.
34. Tan X, Tan D, Li H, Lin Y, Wen Z, Zeng C. circEPSTI1 Acts as a ceRNA to Regulate the Progression of Osteosarcoma. Curr Cancer Drug Targets. 2020;20(4):288-294. doi:10.2174/1568009619666191107140948.
35. 林明亮,林羲疆,陈博韬,周奇,曾参军. 3D打印与腹直肌旁切口治疗骨盆骨折的对照研究[J]. 分子影像学杂志,2020,43(4):692-696. DOI:10.12122/j.issn.1674-4500.2020.04.31.
36. 黄其志,李俊豪,陈大乐,叶东城,曾参军. 3D打印技术在髋臼骨折中的临床应用[J]. 中国卫生标准管理,2019,10(8):22-24. DOI:10.3969/j.issn.1674-9316.2019.08.010.
37. 黄华军,曾参军,张雁儒. 3D打印结合内固定模型库辅助复杂胫骨平台骨折精确化内固定手术[J]. 宁波大学学报(理工版),2019,32(6):23-29. DOI:10.3969/j.issn.1001-5132.2019.06.005.
38. Mingjue Si, Canjun Zeng, Helen Goodluck, Sandi Shen, Subburaman Mohan , Weirong Xing. A small molecular inhibitor of LRRK1 identified by homology modeling and virtual screening suppresses osteoclast function, but not osteoclast differentiation, in vitro. Aging (Albany NY). 2019 May 21; 11(10):3250-3261
39. 肖杏玲,何雪梅,熊日波,曾参军 等. 外固定支架调整记录单在骨搬运治疗大段骨缺损患者中的设计与应用[J]. 创伤外科杂志,2018,20(12):952-953. DOI:10.3969/j.issn.1009-4237.2018.12.024.
40. Si M, Goodluck H, Zeng C, Pan S, Todd EM, Morley SC, Qin X, Mohan S, Xing W. LRRK1 regulation of actin assembly in osteoclasts involves serine 5 phosphorylation of L-plastin. J Cell Biochem. 2018 Dec;119(12):10351-10357. doi: 10.1002/jcb.27377. Epub 2018 Aug 22. PMID: 30136304; PMCID: PMC6218268.
41. Bin Yan, Minjun Huang, Canjun Zeng, Na Yao, Jie Zhang ,Bo Yan,Huaji Jiang ,Xinggui Tian ,Xiang Ao ,Huiyu Zhao,Wen Zhou,Jun Chu,Liping Wang,Cory J. Xian ,Zhongmin Zhang ,Liang Wang. Locally Produced IGF-1 Promotes Hypertrophy of the Ligamentum Flavum via the mTORC1 Signaling Pathway. Cell Physiol Biochem 2018;48:293-303
42. Weirong R Xing , Helen Goodluck , Canjun Zeng and Subburaman Mohan. Role and mechanism of action of leucine-rich repeat kinase 1 in bone. Bone Research (2017) 5, 17003; doi:10.1038/boneres.2017.3
43. M.-J.HUANG,C.-J.ZENG L.WANG. Could leptin-deficient mice be good novel models for diabetic Achilles tendinopathy? Clin Exp Rheumatol 2017; 35 (Suppl. 104): S3.
44. Ouyang H, Deng Y, Xie P, Yang Y, Jiang B, Zeng C, Huang W.Biomechanical comparison of conventional and optimised locking plates for the fixation of intraarticular calcaneal fractures: a finite element analysis.Comput Methods Biomech Biomed Engin. 2017 Sep;20(12):1339-1349.
45. Can-Jun Zeng,Wen-Hua Huang,Hua-Jun Huang,and Zhang-Lin Wu.Laparoscopic Acetabular Fracture Fixation after Three-dimensional Modelling and Printing.Indian J Orthop.2017 Sep-Oct;51(5):620-623.
46. Zeng C, Xing W, Wu Z, Huang H, Huang W.A combination of three-dimensional printing and computer-assisted virtual surgical procedure for preoperative planning of acetabular fracture reduction.Injury. 2016 Oct;47(10):2223-2227.
47. 曾参军,谭新宇,黄华军,黄伟奇,李涛,金大地,张国栋,黄文华等. 基于3D打印的腹直肌旁切口治疗骨盆骨折的临床疗效[J]. 南方医科大学学报,2016,36(2):220-225. DOI:10.3969/j.issn.1673-4254.2016.02.13.
48. Canjun Zeng, Jidong Xiao, Zhanglin Wu, Wenhua Huang. Evaluation of three-dimensional printing for internal fixation of unstable pelvic fracture from minimal invasive para-rectus abdominis approach: a preliminary report. Int J ClinExp Med 2015;8(8):13039-13044.
49. 邓爱文,熊日波,曾参军. 精准医学在外科领域的应用进展[J]. 南方医科大学学报,2015,35(11):1662-1664, DOI:10.3969/j.issn.1673-4254.2015.11.29.
50. Zeng C, Goodluck H, Qin X, Liu B, Mohan S, Xing W. Leucine-rich repeat kinase-1 regulates osteoclast function by modulating RAC1/Cdc42 Small GTPase phosphorylation and activation. Am J Physiol Endocrinol Metab 2016;311-4:E772-E80.
51. 曾参军,张晖,王天兵,秦明和,王磊,金大地,黄文华. 腹直肌旁切口微创治疗地震伤骨盆骨折[J]. 南方医科大学学报,2015(9):1340-1343. DOI:10.3969/j.issn.1673-4254.2015.09.025.
52. Huang H, Hsieh MF, Zhang G, Ouyang H, Zeng C, Yan B, Xu J, Yang Y, Wu Z, Huang W. Improved accuracy of 3D-printed navigational template during complicated tibial plateau fracture surgery.AustralasPhysEngSci Med. 2015 Mar;38(1):109-17.
53. 曾参军,黄文华,韩卫雨,等. 3D打印与腹腔镜辅助的髋臼骨折手术策略[J]. 中华关节外科杂志(电子版),2015(1):25-28.
54. Huajun Huang, Chunling Xiang, Canjun Zeng, Hanbin Ouyang, Kelvin Kian Loong Wong, Wenhua Huang.Patient-specific geometrical modeling of orthopedic structures with high efficiency and accuracy for finite element modeling and 3D printing.Australasian Physical & Engineering Sciences in Medicine.17 November 2015.
55. 邓爱文,熊日波,何伟明,魏东,曾参军. 髋臼骨折中应用3D打印技术术后的康复策略[J]. 南方医科大学学报,2014(4):591-593. DOI:10.3969/j.issn.1673-4254.2014.04.34.
56. 曾参军,樊仕才,李涛. C臂引导下骶骨钉固定骨盆骨折后环不稳的临床疗效[J]. 创伤外科杂志,2012,14(2):127-129. DOI:10.3969/j.issn.1009-4237.2012.02.009.
57. 曾参军,樊仕才,金大地,等. 地震伤骨盆骨折后环不稳的微创治疗[J]. 中国骨与关节损伤杂志,2011,26(6):484-486.
58. 曾参军. 胫骨骨折三种治疗方法的疗效分析[J]. 实用预防医学,2006,13(4):1007-1008. DOI:10.3969/j.issn.1006-3110.2006.04.098.
59. 曾参军. 解剖钢板内固定治疗胫骨远端骨折42例[J]. 广东医学,2005,26(10):1393-1394. DOI:10.3969/j.issn.1001-9448.2005.10.039.
发明专利:(按时间倒序排序):
1、实用新型专利:一种替代横向骨搬运的髓内施压机器人,专利号CN202010271989.5,授权公告日2022.12.09
2、实用新型专利:一种显微脑血管搭桥手术训练模型及其制作方法,专利号CN202210979530.X,授权公告日2022.12.06
3、实用新型专利:一种根骨空心钉植入导向器,专利号ZL 202122084657.9 ,授权公告日2022.3.8
4、实用新型专利:关节镜手术过线器,专利号ZL 202122338137.6,授权公告日2022.2.1
5、实用新型专利:踝关节调节牵引装置,专利号ZL 202121578549.0,授权公告日2021.12.14
6、实用新型专利:一种用于足踝部的冰敷装置,专利号ZL 2020 2 3168965.1,授权公告日2021.11.23
7、实用新型专利:一种骨科钢板抓捏器,专利号CN202120106306.0,授权公告日2021.12.14
8、实用新型专利:一种骨科钢板固定复位棒,专利号CN202120055794.7,授权公告日2021.12.14
9、实用新型专利:一种四肢骨折中多方位固定装置,专利号CN202120106302.2 ,授权公告日2021.9.28
10、实用新型专利:一种纱布生产用固话炉,专利号CN202021932148.6,授权公告日2021.08.13
11、实用新型专利:反向锁定可延长式外固定组合支架,专利号CN202110714366.5,授权公告日2021.08.10
12、实用新型专利:一种快拆式托芯机,专利号CN202021932158.X,授权公告日2021.06.08
13、实用新型专利:一种立式球磨机,专利号CN202021933716.4,授权公告日2021.08.10
14、实用新型专利:一种搅拌球磨机,专利号CN202021933695.6,授权公告日2021.08.03
15、实用新型专利:一种打磨机刀头收纳机构,专利号CN202021933735.7,授权公告日
2021.04.30
16、实用新型专利:一种距骨假体,专利号CN202021936706.6,授权公告日2021.3.26
17、实用新型专利:一种记忆材料跗骨窦支架置换,专利号ZL 202020780911.1,授权公告日2021.2.19
18、创新专利:Talus Neck Universal Locking Device for Talus Neck Fracture,专利号2020103544,授权公告日2021.1.20
19、实用新型专利:一种可用于压疮高风险患者监测的感受器,专利号ZL 202020393530.8,授权公告日2021.1.8
20、实用新型专利:一种距骨颈骨折距骨颈万向锁定装置,专利号ZL 201821748858.6,授权公告日2019.10.15
21、实用新型专利:一种负压引流生物型衬垫 ,专利号ZL201821936731.7,授权公告日2019.10.1
22、实用新型专利:一种3D打印个性化距骨表面置换假体 ,专利号ZL201820596826.2,授权公告日2019.5.10
23、实用新型专利:一种骨软骨取骨器和骨膜骨取骨器 ,专利号ZL201820596880.7,授权公告日2019.5.3
24、实用新型专利:一种髋臼后柱骨折复位固定导向器 ,专利号ZL201720171480.7,授权公告日2018.5.1
25、实用新型专利:一种髌骨骨折复位内固定导向器 ,专利号ZL201720170751.7,授权公告日2018.2.23
26、实用新型专利:一种骨折复位锁定器 ,专利号ZL201720119530.7,授权公告日2018.2.2
27、实用新型专利:可调节角度上肢支具,专利号ZL201621134913.3,授权公告日2017.12.8
28、实用新型专利:3D打印上肢支具 ,专利号ZL201621132203.7 , 授权公告日 2017.10.13
29、实用新型专利:基于CT扫描的带钉道锁定钢板模型的构建方法,专利号CN201510424865.5,授权公告日2015.12.02
30、实用新型专利:髋臼骨折用后柱拉力螺钉3D导航模块的制备方法,专利号CN201510424640.X,授权公告日2015.10.21
科学技术成果
1.罗翔,杨克勤,曾参军,韦平欧,潘愈嘉,李瑶玲 广西自治区科学技术成果登记证书(数字医学研究教学系统)