目录
更新日期:2022年9月23日
姓 名 黄巧冰 性 别
民 族 汉族 导师层次 博士导师
技术职称 教授 导师类型 学术型
最后学历 博士研究生毕业 最后学位 博士
行政职务 Email bing@smu.edu.cn
工作单位 南方医科大学基础医学院 邮政编码 510515
个人简介

   黄巧冰,南方医科大学基础医学院病理生理教研室教授,博士生导师,南粤优秀教师,广东省教学名师,广东省特支计划”教学名师”,广东省师德师风先进个人,南方医科大学本科教学优秀教师,南方医科大学教指委主委。科研工作主要关注疾病发生过程中内皮细胞功能变化的作用和机制。先后主持7项国家自然科学基金的研究任务,发表研究论文150余篇,其中第一和通讯作者发表SCI收录研究论文40余篇。现任中国微循环学会第五届副理事长,中国病理生理学会微循环专业委员会副主任委员,中国病理生理学会休克专业委员会副主任委员,中国微循环学会糖尿病专业委员会副主任委员,广东省病理生理学会常务理事兼监事长等。是美国微循环学会和美国生理学会的正式会员,Frontiers in Physiology Vascular Physiology 副主编,任中国病理生理杂志常务编委,微循环学杂志副主编,是多家国内中英文杂志的编委,同时是AJP Heart Circ、Microcirculation、Burn和Shock等二十多份国际杂志的审稿人。

研究领域

糖尿病血管并发症发生的内皮细胞机制

脓毒症(感染性休克)的发生机制

个人成果

近5年以通讯和共同通讯发表的SCI收录论文:

1. Huang X, Li B, Hu J, Liu Z, Li D, Chen Z, Huang H, Chen Y, Guo X, Cui Y, Huang Q (2022), Advanced glycation endproducts mediate chronic kidney injury with characteristic patterns in different stages. Front. Physiol. Sec. Vascular Physiology. doi:10.3389/fphys.2022.977247

2. Li B, Huang X, Wei J, Huang H, Liu Z, Hu J, Zhang Q, Chen Y, Cui Y, Chen Z, Guo X, Huang Q*. Role of moesin and its phosphorylation in VE-cadherin expression and distribution in endothelial adherens junctions. Cell Signal. 2022 Sep 10:110466.

3. Zhang Q, Wei J, Liu Z, Huang X, Sun M, Lai W, Chen Z, Wu J, Chen Y, Guo X, Huang Q*. STING signaling sensing of DRP1-dependent mtDNA release in kupffer cells contributes to lipopolysaccharide-induced liver injury in mice. Redox Biol. 2022 Jun 15;54:102367. doi: 10.1016/j.redox.2022.102367.

4. Mao L#, Sun M#, Chen Z, Zeng Z, Wu J, Chen Z*, Zhang W*, Huang Q*. The Pyruvate Dehydrogenase Complex Mitigates LPS-Induced Endothelial Barrier Dysfunction by Metabolic Regulation. Shock. 2022 Jun 1;57(6):308-317.

5. Zou Z#, Li L#, Li Q, Zhao P, Zhang K, Liu C, Cai D, Maegele M*, Gu Z*, Huang Q*. The role of S100B/RAGE-enhanced ADAM17 activation in endothelial glycocalyx shedding after traumatic brain injury. J Neuroinflammation. 2022 Feb 11;19(1):46. doi: 10.1186/s12974-022-02412-2.

6. Chen Y, Liu Z, Chen H, Huang X, Huang X, Lei Y, Liang Q, Wei J, Zhang Q, Guo X, Huang Q*. p53 SUMOylation Mediates AOPP-Induced Endothelial Senescence and Apoptosis Evasion. Front Cardiovasc Med. 2022 Feb 3;8:795747. doi: 10.3389/fcvm.2021.795747.

7. Sun M#, Li J#, Mao L, Wu J, Deng Z, He M, An S, Zeng Z*, Huang Q*, Chen Z*. p53 Deacetylation Alleviates Sepsis-Induced Acute Kidney Injury by Promoting Autophagy. Front Immunol. 2021 Jul 14;12:685523. doi: 10.3389/fimmu.2021.685523.

8. Zhang Y, Sha T, Wu F, Hu H, Chen Z, Li H, Han J, Song W, Huang Q*, Zeng Z*. Hypertension in Patients Hospitalized with COVID-19 in Wuhan, China. Int Heart J. 2021 Mar 30;62(2):337-343.

9. Zhang SS, Hu JQ, Liu XH, Chen LX, Chen H, Guo XH, Huang QB. Role of Moesin Phosphorylation in Retinal Pericyte Migration and Detachment Induced by Advanced Glycation Endproducts. Front Endocrinol (Lausanne). 2020 Nov 18;11:603450.   https://doi.org/10.3389/fendo.

10. Chen L, Cui Y, Li B, Weng J, Wang W, Zhang S, Huang X, Guo X*, Huang Q*. Advanced glycation end products induce immature angiogenesis in in vivo and ex vivo mouse models.  Am J Physiol Heart Circ Physiol. 2020 Mar 1;318(3):H519-H533.

11. Wu J#, Deng Z#, Sun M, Zhang W, Yang Y, Zeng Z, Wu J, Zhang Q, Liu Y, Chen Z, Guo X, Zhao KS, Huang Q*, Chen Z*. Polydatin protects against lipopolysaccharide-induced endothelial barrier disruption via SIRT3 activation. Lab Invest. 2020 Apr;100(4):643-656.

12. Chen L, Zhou T, Wu N, O'Brien A, Venter J, Ceci L, Kyritsi K, Onori , Gaudio E, Sybenga A, Xie L, Wu C, Fabris L, Invernizzi P, Zawieja D, Liangpunsakul S, Meng F, Francis H, Alpini G*, Huang Q*, Glaser S*. Pinealectomy or light exposure exacerbates biliary damage and liver fibrosis in cholestatic rats through decreased melatonin synthesis. Biochim Biophys Acta Mol Basis Dis. 2019 Jun 1;1865(6):1525-1539.

13. Cheng A, Lu Y, Huang Q*, Zuo Z*. Attenuating oxygen-glucose deprivation-caused autophagosome accumulation may be involved in sevoflurane postconditioning-induced protection in human neuron-like cells. Eur J Pharmacol. 2019 Jan 30;849:84-95. 

14. Weng J, Yu L, Chen Z, Su H, Yu S, Zhang Y, Lei X, Chen L, Cui Y, Huang Q*, Jiang Y*, Guo X*. β-catenin phosphorylation at Y654 and Y142 is crucial for high mobility group box-1 protein-induced pulmonary vascular hyperpermeability. J Mol Cell Cardiol. 2018 Dec 25;127:174-184.

15. Wang W, Weng J, Yu L, Huang Q*, Jiang Y*, Guo X*. Role of TLR4-p38 MAPKHsp27 signal pathway in LPS-induced pulmonary epithelial hyperpermeability. BMC Pulm Med. 2018 Nov 27;18(1):178.

16. Wu J, Zhang W, Liu X, Wu L, He G, Li P, Guo X, Chen Z, Huang Q*. Apocynin protects endothelial cells from endoplasmic reticulum stress-induced apoptosis via IRE1-α engagement. Mol Cell Biochem. 2018 Dec; 449(1-2): 257-265.

17. Li P, Chen D, Cui Y, Zhang W, Weng J, Yu L, Chen L, Chen Z, Su H, Yu S, Wu J, Huang Q*, Guo X*. Src Plays an Important Role in AGE-Induced Endothelial Cell Proliferation, Migration, and Tubulogenesis. Front Physiol. 2018 Jun 21;9:765. eCollection 2018.

18. Zhou X, Weng J, Xu J, Xu Q, Wang W, Zhang W, Huang Q*, Guo X*. mDia1 is Crucial for Advanced Glycation End Product-Induced Endothelial Hyperpermeability. Cell Physiol Biochem. 2018;45(4):1717-1730.

19. Xiao Y, Wu J, Yuan Y, Guo X, Chen B, Huang Q*. Effect of moesin phosphorylation on high‑dose sphingosine‑1‑phosphate‑induced endothelial responses. Mol Med Rep. 2018(17): 1933-1939.