周平正，女，教授，博士生导师。博士毕业于中国科学院上海药物研究所，先后入选德国洪堡学者、广东省青年珠江学者和广州市珠江科技新星等人才项目，获得中科院百篇优秀博士论文奖、日本神经科学会Travel award和广东省高校青年教师教学大赛二等奖；已先后主持国家自然科学基金、广东省和广州市自然科学基金等省部级以上课题10项，目前以第一或通讯作者（含共同）在PNAS、Brit J Pharmacol、Pharmacol Res、JBC等期刊发表论文30篇。主要研究方向为运用基因敲除小鼠、电生理学和分子细胞生物学技术研究离子通道在天然免疫信号转导中的作用、机制与药物发现。担任中国药理学会抗炎免疫药理学专委会常务委员（青年），广东省药理学会药物筛选与评价专委会副主任委员。 

离子通道在天然免疫信号转导中的作用、机制与药物发现。

1. Zhou P, Yu H, Gu M, Nan F, Gao Z, Li M (2013) Phosphatidylinositol 4,5-bisphosphate alters pharmacological selectivity for epilepsy-causing KCNQ potassium channels. Proceedings of the National Academy of Sciences of the United States of America 110: 8726–8731

2. Zhang Q*, Zhou P*, Chen Z, Li M, Jiang H, Gao Z, Yang H (2013) Dynamic PIP2 interactions with voltage sensor elements contribute to KCNQ2 channel gating. Proceedings of the National Academy of Sciences of the United States of America 110: 20093–20098  

3. Cao Y, Chen S, Liang Y, Wu T, Pang J, Liu S^#, Zhou P^# (2018) Inhibition of hyperpolarization-activated cyclic nucleotide-gated channels by beta-blocker carvedilol. British Journal of Pharmacology. 175(20):3963-3975

4. Zhang, X., Lin, X., Luo, H., Zhi, Y., Yi, X., Wu, X., Duan, W., Cao, Y., Pang, J., Liu, S., Zhou, P^# (2022) Pharmacological inhibition of Kv1.3 channel impairs TLR3/4 activation and type I IFN response and confers protection against Listeria monocytogenes infection. Pharmacological research, 106112;178:106192.

5. Wu, XY., Lv, JY., Zhang, SQ., Yi, X., Xu, ZW., Zhi, YX., Zhao, BX., Pang, JX., Yung, K. K. L^#, Liu, SW^#, and Zhou, P^# (2021) ML365 inhibits TWIK2 channel to block ATP-induced NLRP3 inflammasome, Acta pharmacologica Sinica 43(4):992-1000

6. Zhi, Y., Liu, J., Kuang, P., Zhang, X., Xu, Z., Chen, Y., Lin, X., Wu, X., Zhou, P^#, Chen, J^# (2022) Novel DCPIB analogs as dual inhibitors of VRAC/TREK1 channels reduced cGAS-STING mediated interferon responses. Biochemical pharmacology 199:114988.

7. Ding L, Jiang P, Xu X, Lu W, Yang C, Li L, Zhou P^#, Liu S^# (2021) T-type calcium channels blockers inhibit HSV-2 infection at the late stage of genome replication. European journal of pharmacology 892: 173782.

8. Lv J, Liang Y, Zhang S, Lan, Q, Xu Z, Wu X, Kang L, Ren J; Cao Y, Wu T, Lin K, Yung, K, Cao X^#, Pang J^#, Zhou P^# (2019) DCPIB, an inhibitor of volume-regulated anion channels, distinctly modulates K2P channels. ACS Chemical Neuroscience 19;10(6):2786-2793

9 Zhou P*, Polovitskaya MM*, Jentsch TJ (2018) LRRC8 amino-termini influence pore properties and gating of volume-regulated VRAC anion channels. Journal of biological chemistry 293(35):13440-13451

10. Ding L, Jiang P, Xu X, Lu W, Yang C, Zhou P^#, Liu S^#. Resveratrol promotes HSV-2 replication by increasing histone acetylation and activating NF-κB (2019) Biochem Pharmacol. 171:113691.

11. Xu Z, Chen Z; Wu X; Zhang L; Cao Y; Zhou P^#. Distinct Molecular Mechanisms Underlying Potassium Efflux for NLRP3 Inflammasome Activation (2020). Front. Immunol. 11:609441.

12. Chen S, Xu Y, Liang YM, Cao Y, Lv JY, Pang JX, Zhou P (2018) Identification and characterization of a series of novel HCN channel inhibitors. Acta pharmacologica Sinica. 40(6):746-754