毕业于上海交通大学附属第九人民医院口腔颌面-头颈肿瘤科，获口腔临床医学博士学位。曾于意大利siena大学医院及日本大阪齿科大学访问学者。学术任职：广东省口腔医学会口腔急诊专委会副主任委员，中华口腔医学会老年口腔医学专委会委员，中华口腔医学会口腔颌面-头颈肿瘤专委会委员，中国整形美容学会精准与数字医学分常务理事，广东省口腔医学会口腔颌面外科专委会常委，广东省颌面－头颈外科专业委员会常委，广东省抗癌协会头颈肿瘤专委会常委，广东省保健协会数字口腔分化副主任委员，广东省老年保健协会口腔临床专业委员会副主任委员，广东省保健协会口腔保健专业委员会常委，广东省口腔医师协会理事，广东省语言残疾鉴定专家库成员，广州市整形美容外科分会委员等。担任《Frontiers in Dental Medicine》《南方医科大学学报》、《分子诊断与治疗杂志》《口腔疾病防治杂志》等期刊编委。国家自然科学基金一审专家、广东省自然科学基金、广东省科技计划项目、广东省医学科研基金，广州市科技计划项目、山东省自然科学基金评审专家，山东省科技进步奖评审专家。从事口腔颌面-头颈肿瘤的基础和临床研究。擅长于口腔颌面-头颈肿瘤的根治及术后缺损的重建。研究方向为：口腔鳞癌的发病及防治。主持国家自然科学基金面上项目1项，省部级课题5项，省卫生厅及教育厅课题各1项，海外合作课题一项，院校级课题5项。第一作者及通讯作者发表SCI文章19篇，IF>5分10篇，中科院大类1区1篇，小类1区2篇，2区6篇。

从事口腔鳞癌发生发展的机制研究，尤其是关注长链非编码RNA在口腔鳞癌发生发展过程中的作用及其机制研究以及铁死亡与化疗抵抗的关系；以第一作者及通讯作者、共同通讯作者发表SCI文章26篇，其中IF>5分的10篇

1. Li J, Qiao Z, Li Y, Lu X, Shao T, Lv X*. Bioinformatic analysis indicated that STARD4-AS1 might be a potential ferroptosis-related biomarker of oral squamous cell carcinoma. HELIYON. 2024 Jun 17;10(12):e33193. doi: 10.1016/j.heliyon.2024.e33193. eCollection 2024 Jun 30. 通讯作者

2. Wang RY, Shao TR, Liu CD, Zhang XG, Lv XZ*. A modified supraclavicular artery island flap for reconstruction of oral and maxillofacial defects. Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology,2024,May 29:S2212-4403(24)00316-X. doi: 10.1016/j.oooo.2024.05.013. Online ahead of print 通讯作者

3. Song Y, Tian Y, Lu X, Chen G, Lv X*. Prognostic value of 18 F-FDG PET radiomics and sarcopenia in patients with oral squamous cell carcinoma. Med Phys. 2024, Feb 23;28(5):e18083. doi: 10.1111/jcmm.18083. Online ahead of print. 通讯作者

4. Wu S, Lv X*, Wei H, Wu J, Liu S, Li X, Song J, Zou C, Ai Y. Integrated analysis of single-cell RNA-seq and bulk RNA-seq unravels the molecular feature of M2 macrophages of head and neck squamous cell carcinoma. J Cell Mol Med. 2024 Feb 23;28(5):e18083. doi: 10.1111/jcmm.18083. Online ahead of print. 共同一作

5. Wu S, Lv X*, Wei H, Chen W, Zheng J, Li X, Song J, Ai Y, Zou C.Circ-ILF2 in oral squamous cell carcinoma promotes cisplatin resistance and induces M2 polarization of macrophages. J Cell Mol Med. 2023 Dec; 27(24):4133-4144.doi: 10.1111/jcmm.17998. Epub 2023 Oct 20. 共同一作

6. Siyuan W, Xiaozhi L*, Jialin W, Wei H, Liu S, Zou C, Song J, Xia L, Yilong A.The Potential Mechanism of Curcumin in Treating Oral Squamous Cell Carcinoma Based on Integrated Bioinformatic Analysis.Int J Genomics. 2023 Oct 14:2023:8860321.doi: 10.1155/2023/ 8860321.eCollection 2023. 共同一作

7. Liu L, Zou C, Lv X*, Wei H, Wu S, Song J, Tang Z, Luo H, Li X, Ai Y.SP2-induced circPUM1 modulates chemoresistance and nature killer cell toxicity in oral squamous cell carcinoma.J Cell Mol Med. 2023 Aug 9. doi: 10.1111/jcmm.17888. Online ahead of print. 共同一作

8. Lu X, Tian Y, Huang J, Li F, Shao T, Huang G, Lv XZ*. Evaluating the Prognosis of Oral Squamous Cell Carcinoma Patients via L3 Skeletal Muscle Index. Oral Dis. 2023 Apr;29(3):923-932. 通讯作者

9. Wu Q, Shao T, Huang G, Zheng Z, Jiang Y, Zeng W*, Lv X*.FDCSP Is an Immune-Associated Prognostic Biomarker in HPV-Positive Head and Neck Squamous Carcinoma.Biomolecules. 2022 Oct 12;12(10):1458.通讯作者

10. Ye H, Zheng Z, Song Y, Huang G, Wu Q, Ai Y*, Lv X*.Metabolism-Related Bioinformatics Analysis Reveals That HPRT1 Facilitates the Progression of Oral Squamous Cell Carcinoma In Vitro.J Oncol. 2022,2022:7453185. 通讯作者

11. Zou C, Li X, Wei H, Wu S, Song J, Tang Z, Luo H, Li X*, Ai Y.Circular GOLPH3 RNA exerts oncogenic effects in vitro by regulating the miRNA-1299/LIF axis in oral squamous cell carcinoma.Bioengineered. 2022,13(4):11012-11025. 唯一通讯

12. Zou C*, Lv X*, Wei H*, Wu S, Song J, Tang Z, Liu S, Li X*, Ai Y*.Long non-coding RNA LINC00472 inhibits oral squamous cell carcinoma via miR-4311/GNG7 axis.Bioengineered.2022, 13(3):6371-6382. 共同第一

13. Huang GZ, Chen ZQ, Wu J, Shao TR, Zou C, Ai Y, Lv XZ*.Pan-cancer Analyses of Tumor Microenvironment Reveal that Ubiquitin Conjugating Enzyme E2C Might Be a Potential Immunotherapy Target. J Immunol Res. 2021, 10.1155 通讯作者

14. Zou C*, Li X*, Lv X*, Wu S, Song J, Tang Z, Luo H, Wei H, Ai Y. Circular RNA Mitochondrial Translation  Optimization 1

 homologue (CircMTO1) induced by Zinc Finger Protein 460 (ZNF460) promotes oral squamous cell carcinoma progression through the microRNA miR-320a / Alpha Thalassemia/Mental Retardation, X-linked (ATRX) axis. Bioengineered, 2021 ,12(2):9585-9597. 共同第一

15. Huang GZ, Lu ZY, Rao Y, Gao H, Lv XZ*.Screening and Identification of Autophagy-related Biomarkers for Oral Squamous Cell Carcinoma(OSCC) via Integrated Bioinformatics Analysis. J Cell Mol Med, 2021, 25(9):4444-4454.  通讯作者

16. Zou C, Wu S, Wei H, Luo H, Tang Z, Li X, Lv X*, Ai Y*. LINC01355 contributes to malignant phenotype of oral squamous cell carcinoma and cytotoxic T Cell infiltration via activating Notch signaling pathway. J Immunol Res. 2021:1830790.  共同通讯

17. Ai Y, Liu SW, Luo H, Wu S, Wei H, Tang Z, Li X, Lv X*, Zou C *.METTL3 Intensifies the Progress of Oral Squamous Cell Carcinoma via Modulating the m6A Amount of PRMT5 and PD-L1. J Immunol Res. 2021:6149558 共同通讯

18. Huang GZ, Wu QQ, Zheng ZN, Shao TR, Li F, Lu XY, Ye HY, Chen GX, Song YX, Zeng WS, Ai YL, Lv XZ*. Bioinformatics analyses indicate that cathepsin G (CTSG) is a potential immune-related biomarker in Oral squamous cell carcinoma (OSCC).Onco Targets Ther. 2021, 14:1275-1289. 通讯作者

19. Zheng ZN，Huang GZ, Wu QQ,Ye HY, Zeng WS, Lv XZ.NF-κB-mediated lncRNA AC007271.3 promotes carcinogenesis of oral squamous cell carcinoma by regulating miR-125b-2-3p/Slug. Cell Death Dis,2020,11(12):1015 通讯作者

20. Huang GZ, Wu QQ, Zheng ZN, Shao TR, Chen YC, Zeng WS, Lv XZ. M6A-related bioinformatics analysis reveals that HNRNPC facilitates progression of OSCC via EMT.Aging (Albany NY). 2020,12(12):11667-11684.  通讯作者

21. Wu Q, Zhao M, Huang G, Zheng Z, Chen Y, Zeng W, Lv X.Fibroblast Activation Protein (FAP) Overexpression Induces Epithelial–Mesenchymal Transition (EMT) in Oral Squamous Cell Carcinoma by Down-Regulating Dipeptidyl Peptidase 9 (DPP9).OncoTargets and Therapy, 2020,13:2599-2611通讯作者

22. Shao TR, Zheng ZN, Chen YC, Wu QQ, Huang GZ, Li F, Zeng WS*, Lv XZ*.LncRNA AC007271.3 Promotes Cell Proliferation, Invasion, Migration and Inhibits Cell Apoptosis of OSCC via the Wnt/b-catenin Signaling Pathway. Life Sci. 2019, 239:117087. 通讯作者

23. Huang GZ, Wu QQ, Zheng ZN, Shao TR, Lv XZ*. Identification of candidate biomarkers and analysis of prognostic values in oral squamous cell carcinoma.Front Oncol. 2019,9:1054.  通讯作者

24. Shao T, Huang J, Zheng Z, Wu Q, Liu T*, Lv X*. SCCA, TSGF, and the Long Non-Coding RNA AC007271.3 are effective biomarkers for diagnosing oral squamous cell Carcinoma. Cell Physiol Biochem,2018,47(1)26-38 通讯作者

25. X-Z Lv*, M-Y Zheng, Z-Q Lin, M Zhao, H Wang, W-S Zeng*. The fusion protein of human granzyme B and truncated VEGF represses angiogenesis and tumor growth of human oral squamous cell carcinoma. Oral Dis. 2016,22(7):688-96  第一作者

26. Wang H, Wu Q, Liu Z, Luo X, Fan Y, Liu Y, Zhang Y, Hua S, Fu Q, Zhao M, Chen Y, Fang W*, Lv X*. Down-regulation of FAP suppresses cell proliferation and metastasis through PTEN/PI3K/AKT and Ras-ERK signaling in oral squamous cell carcinoma. Cell Death Dis,2014,5(4): e1155. 通讯作者

27. Xiaozhi Lv, Yuichi Ohnishi, Katsuko Horli, Xueming Yin, Yi-ru Fang, Kenji Kakudo and Buling Wu.Expression of MMP-2 and HB-EGF in keratocysHc odontogenic tumors. J of Osaka dental university, 2013,47(2),257-261. 第一作者