南方医科大学教师信息

关闭

1. 个人简介
2. 研究领域
3. 发表论文

更新日期：2025年7月11日

姓名	陈薪	性别	女
民族	汉族	导师层次	博士导师
技术职称	主任医师	导师类型	专业型
最后学历	硕士研究生毕业	最后学位	医学博士学位
行政职务	主任	Email	zhiduoxinrun@163.com
工作单位	南方医科大学珠江医院	邮政编码

个人简介

陈薪，女，南方医科大学珠江医院，生殖医学/辅助生殖科主任，主任医师、医学博士、博士研究生导师、博士后合作导师。

耶鲁大学访问科学研究家。从事生殖医学的医疗、教学和科研工作20余年，在生殖内分泌、女性不孕症和辅助生殖技术等方面具有丰富的经验和深入的研究,对生殖医学、不孕症及疑难病症有独到的见解，已帮助众多家庭获得了健康的孩子。曾是国家临床重点专科和全国首批人类辅助生殖技术培训基地的专业技术学科骨干。创建了南方医科大学一家三甲医院生殖医学中心IVF-ET/ICSI全体系，培养了一系列生殖医学专业人才，并带领科室通过了ISO-9001:2015质量管理体系认证，培养出一批质量控制和管理内审员。荣获首批“广东省杰出青年医学人才”、首届“亚美医学基金会（MMAAP）生殖医学奖”。在“中国创新方法大赛广东区域赛”中获奖两项。主持或完成国家自然科学基金和省部级等课题多项，专利授权6项。以通讯作者/第一作者发表SCI论文20余篇。

研究领域

生殖医学，包括女性卵巢功能在体保存的分子机制研究和临床研究、原始卵泡的激活机制、薄型子宫内膜的修复、生殖医学智能化建设等。

个人成果

[1] Li X, Li C, Yang J, Lin M, Zhou X, Su Z, Zhang Y, Li X, Chen X. Associations of the levels of adipokines and cytokines in individual follicles with in vitro fertilization outcomes in women with different ovarian reserves. J Ovarian Res. 2025 Jan 22;18(1):11. doi: 10.1186/s13048-025-01594-6.

[2] Liu S, Wang W, Liu H, Wei H, Weng Y, Zhou W, Zhang X, He S, Chen Y, Wang Y, Zhang M, Chen X. Berberine promotes primordial follicle activation and increases ovulated oocyte quantity in aged mice. Mol Med. 2024 Dec 20;30(1):251. doi: 10.1186/s10020-024-01042-z.

[3] Zhang Z, Li X, Guo S, Chen X. A Mendelian randomization study on causal relationship between metabolic factors and abnormal spermatozoa. Transl Androl Urol. 2024 Sep 30;13(9):2005-2015. doi: 10.21037/tau-24-187.

[4] Li X, Yang J, Blockeel C, Lin M, Tian X, Wu H, Cao Y, Deng L, Zhou X, Xie J, Hu Y, Chen X. Association of severity of menstrual dysfunction with cardiometabolic risk markers among women with polycystic ovary syndrome. Acta Obstet Gynecol Scand. 2024 Aug;103(8):1606-1614. doi: 10.1111/aogs.14863.

[5] Qi Z, Zhao Q, Yu Z, Yang Z, Feng J, Song P, He X, Lu X, Chen X, Li S, Yuan Y, Cai Z. Assessing the Impact of PM2.5-Bound Arsenic on Cardiovascular Risk among Workers in a Non-ferrous Metal Smelting Area: Insights from Chemical Speciation and Bioavailability. Environ Sci Technol. 2024 May 14;58(19):8228-8238. doi: 10.1021/acs.est.3c10761.

[6] Li CJ, Zhan YD, Zhou XL, Yang J, Deng L, Li XL, Chen X. Value of Intrauterine Autologous Platelet-Rich Plasma Therapy on Endometrial Receptivity: A Literature Review. Curr Med Sci. 2023 Dec;43(6):1075-1083. doi: 10.1007/s11596-023-2816-4.

[7] Li X, Guo P, Blockeel C, Li X, Deng L, Yang J, Li C, Lin M, Wu H, Cai G, Hu Y, Chen X. Storage duration of vitrified embryos does not affect pregnancy and neonatal outcomes after frozen-thawed embryo transfer. Front Endocrinol (Lausanne). 2023 Mar 14;14:1148411. doi: 10.3389/fendo.2023.1148411.

[8] Chai X, Wen L, Song Y, He X, Yue J, Wu J, Chen X, Cai Z, Qi Z. DEHP exposure elevated cardiovascular risk in obese mice by disturbing the arachidonic acid metabolism of gut microbiota. Sci Total Environ. 2023 Jun 1;875:162615. doi: 10.1016/j.scitotenv.2023.162615.

[9] He X, Zhao Q, Chai X, Song Y, Li X, Lu X, Li S, Chen X, Yuan Y, Cai Z, Qi Z. Contribution and Effects of PM2.5-Bound Lead to the Cardiovascular Risk of Workers in a Non-Ferrous Metal Smelting Area Considering Chemical Speciation and Bioavailability. Environ Sci Technol. 2023 Jan 31;57(4):1743-1754. doi: 10.1021/acs.est.2c07476.

[10] Yang S, Wen L, Chai X, Song Y, Chen X, Chen ZF, Li R, Dong C, Qi Z, Cai Z. The protective effects of taurine and fish oil supplementation on PM2.5-induced heart dysfunction among aged mice: A random double-blind study. Sci Total Environ. 2022 Dec 10;851(Pt 1):157966. doi: 10.1016/j.scitotenv.2022.157966.

[11] Li B, Wang W, Huang Y, Han L, Li J, Zheng N, Wu Z, Zhang X, Li X, Deng L, Lin M, Chen X, Zhang M. Lithium treatment promotes the activation of primordial follicles through PI3K/Akt signaling†. Biol Reprod. 2022 Oct 11;107(4):1059-1071. doi: 10.1093/biolre/ioac150.

[12] Zhang X, Zhang W, Wang Z, Zheng N, Yuan F, Li B, Li X, Deng L, Lin M, Chen X, Zhang M. Enhanced glycolysis in granulosa cells promotes the activation of primordial follicles through mTOR signaling. Cell Death Dis. 2022 Jan 27;13(1):87. doi: 10.1038/s41419-022-04541-1.

[13] Pan P, Shen M, Yu Z, Ge W, Chen K, Tian M, Xiao F, Wang Z, Wang J, Jia Y, Wang W, Wan P, Zhang J, Chen W, Lei Z, Chen X, Luo Z, Zhang Q, Xu M, Li G, Li Y, Wu J. SARS-CoV-2 N protein promotes NLRP3 inflammasome activation to induce hyperinflammation. Nat Commun. 2021 Aug 2;12(1):4664. doi: 10.1038/s41467-021-25015-6.

[14] Deng L, Chen X, Blockeel C, Ye DS, Chen SL. Intramuscular injection of human chorionic gonadotropin prior to secretory transformation in patients undergoing frozen-thawed embryo transfer cycles. Reprod Biol Endocrinol. 2020 May 25;18(1):52. doi: 10.1186/s12958-020-00606-y.

[15] Zhang QY, Li X, Zhou XY, Li Y, Zhang J, Zhang XF, Liu YD, Chen YX, Wu XM, Ma LZ, Chen X, Chen SL. Study of differential proteomics in granulosa cells of premature ovarian insufficiency (POI) and the roles and mechanism of RAC1 in granulosa cells. Mol Cell Endocrinol. 2022 Sep 15;555:111719. doi: 10.1016/j.mce.2022.111719.

[16] Li Y, Zhang J, Liu YD, Zhou XY, Chen X, Zhe J, Zhang QY, Zhang XF, Chen YX, Wang Z, Chen SL. Long non-coding RNA TUG1 and its molecular mechanisms in polycystic ovary syndrome. RNA Biol. 2020 Dec;17(12):1798-1810. doi: 10.1080/15476286.2020.1783850.

[17] Yang J, Lin M, Tian X, Li C, Wu H, Deng L, Li X, Chen X. Serum adiponectin level is negatively related to insulin resistance in women with polycystic ovary syndrome. Endocr Connect. 2024 Dec 13;14(1):e240401. doi: 10.1530/EC-24-0401.

[18] Deng L, Chen X, Blockeel C, Ye DS, Chen SL. Intramuscular injection of human chorionic gonadotropin prior to secretory transformation in patients undergoing frozen-thawed embryo transfer cycles. Reprod Biol Endocrinol. 2020 May 25;18(1):52. doi: 10.1186/s12958-020-00606-y.