个人荣誉:
2015学年南方医科大学南方医院优秀临床带教
2015年度南方医科大学第5届中青年教师本科课程教学竞赛二等奖
2016年度南方医科大学第6届中青年教师本科课程教学竞赛二等奖
2016年度全国口腔院校青年教师理论授课技能竞赛三等奖
2016学年校级教学优秀三等奖
2018年广东省杰出青年医学人才
2018年广东省实力中青年医师
2018年住院医师规范化培训口腔医学专业师资培训研讨会二等奖
2021年第七届羊城好医生
2022年第二届昌岗地区十佳青年
学术专著:
口腔中级医师考试题集
代表性论文:
1.Yu GT, Zhu WX, Zhao YY, Cui H, Chen H, Chen Y, Ning TT, Rong MD, Rao L, Ma DD. 3D-printed bioink loading with stem cells and cellular vesicles for periodontitis-derived bone defect repair. Biofabrication. (IF2023=8.2,中科院小类分区=2区)
2.Luo J, Ning T, Li X, Jiang T, Tan S, Ma DD*. Targeting IL-12 family cytokines: A potential strategy for type 1 and type 2 diabetes mellitus. Biomed Pharmacother. (IF2023=6.9,中科院小类分区=2区)
3.Zou XH, Lei Q, Luo XH, Yin JY, Chen SL, Hao CB, Liu SY*, Ma DD*. Advances in biological functions and applications of apoptotic vesicles. Cell Communication and Signaling. (IF2022=8.4,中科院小类分区=2区)
4.Wang YZ, Luo XH, Xiang XZ, Hao CB, Ma DD*. Roles of Bacterial Extracellular Vesicles in Systemic Diseases. Frontiers in Microbiology. (IF2022=5.2,中科院小类分区=2区)
5.Jiang T, Miao SH, Shen JJ, Song WJ, Tan SL, Ma DD*. Enhanced effects of antagomiR-3074-3p-conjugated PEI-AuNPs on the odontogenic differentiation by targeting FKBP9. Journal of Tissue Engineering. 2023; 14: 1-17. (IF2022=8.2,中科院小类分区=2区)
6.Luo XH, Feng WQ, Huang SJ, Miao SH, Jiang T, Lei Q, Yin JY, Zhang S, Bai XC, Hao CB, Li WZ*, Ma DD*.Odontoblasts release exosomes to regulate the odontoblastic differentiation of dental pulp stem cells. Stem Cell Research and Therapy. 2023 Jul 8;14(1):176. (IF2022=7.5,中科院小类分区=2区)
7.Tan SL, Chen SS, Lei Q, Ma DD*. 3A novel rapidly mineralized biphasic calcium phosphate with high acid-resistance stability for long-term treatment of dentin hypersensitivity. Dent Mater. 2023,27;S0109-5641(23)00024-6.(IF 2022=5, 中科院小类分区=1区)
8.Chen SL, Lei Q, Zou XH, Ma DD*. The Role and Mechanisms of Gram-negative Bacterial Outer Membrane Vesicles in Inflammatory Diseases. Frontiers in Immunology. 2023; 14:1157813. (IF2022=7.3,中科院小类分区=2区)
9.Ruan Q, Guan P, Qi W, Li J, Xi M, Xiao L, Zhong S, Ma D*, Ni J*. Porphyromonas gingivalis regulates atherosclerosis through an immune pathway. Front Immunol. 2023,14;14:1103592. (IF 2022=7.3, 中科院小类分区=2区)
10.Ruan Q, Tan SL, Guo L, Ma DD*, Wen J*. Prevascularization techniques for dental pulp regeneration: potential cell sources, intercellular communication and construction strategies. Front Bioeng Biotechnol. 2023;11:1186030. (IF2022=5.7,中科院小类分区=3区)
11.Yin JY, Lei Q, Luo XH, Jiang T, Zou XH, Abraham Schneider, Hockin H K Xu, Zhao L*, Ma DD*. Degradable hydrogel fibers encapsulate and deliver metformin and periodontal ligament stem cells for dental and periodontal regeneration. J Appl Oral Sci. 2023;31:e20220447. (IF2022=2.7,中科院小类分区=3区)
12.Luo X, Yin J, Miao S, Feng W, Ning T, Xu S, Huang S, Zhang S, Liao Y, Hao C, Wu B, Ma D*. mTORC1 promotes mineralization via p53 pathway.FASEB J. 2021;35(2):e21325.(IF 2021=5.834, 中科院小类分区=2区)
13.Yin J, Luo X, Feng W, Miao S, Ning T, Lei Q, Jiang T, Ma D*. Multidifferentiation potential of dental-derived stem cells. World J Stem Cells. 2021;13(5):342-365.(IF 2021=5.247, 中科院小类分区=3区)
14.Ning T, Shao J, Zhang X, Luo X, Huang X, Wu H, Xu S, Wu B, Ma D*. Ageing affects the proliferation and mineralization of rat dental pulp stem cells under inflammatory conditions. Int Endod J. 2020,53(1):72-83.(IF 2020=5.264, 中科院小类分区=2区)
15.Zhang X, Ning T, Wang H, Xu S, Yu H, Luo X, Hao C, Wu B*, Ma D*. Stathmin regulates the proliferation and odontoblastic/osteogenic differentiation of human dental pulp stem cells through Wnt/β-catenin signaling pathway. J Proteomics. 2019,202:103364.(IF 2019=3.509, 中科院小类分区=2区)
16.Yu H, Zhang X, Song W, Pan T, Wang H, Ning T, Wei Q, Xu HHK, Wu B*, Ma D*. Effects of 3D Bioprinting Alginate/Gelatin Hydrogel Scaffold Extract on Proliferation and Differentiation of Human Dental Pulp Stem Cells. J Endod. 2019,45(6):706-715.(IF 2019=3.118, 中科院小类分区=2区)
17.Wang H, Ning T, Song C, Luo X, Xu S, Zhang X, Deng Z, Ma D*, Wu B*. Priming integrin α5 promotes human dental pulp stem cells odontogenic differentiation due to extracellular matrix deposition and amplified extracellular matrix-receptor activity. J Cell Physiol. 2019,234(8):12897-12909.(IF 2019=5.546, 中科院小类分区=2区)
18.Ma D#, Yu H#, Xu S, Wang H, Zhang X, Ning T, Wu B*. Stathmin Inhibits Proliferation and Differentiation of dental pulp stem cells Via Sonic Hedgehog/Gli. J Cell Mol Med. 2018,22(7):3442-3451.(IF 2018=4.658, 中科院小类分区=2区)
19.Ma D#, Cui L#, Gao J, Yan W, Liu Y, Xu S, Wu B. Proteomic analysis of mesenchymal stem cells from normal and deep carious dental pulp. PLoS One. 2014,9(5):e97026.(IF 2014=3.534, 中科院小类分区=3区)
20.Ma D, Gao J, Yue J, Yan W, Fang F, Wu B. Changes in proliferation and osteogenic differentiation of stem cells from deep caries in vitro. J Endod. 2012,38(6):796-802.(IF 2012=2.179, 中科院小类分区=2区)
21.Ma D#, Ma Z#, Zhang X, Wang W, Yang Z, Zhang M, Wu G, Lu W, Deng Z, Jin Y. Effect of age and extrinsic microenvironment on the proliferation and osteogenic differentiation of dental pulp stem cells in vitro. J Endod. 2009,35(11):1546-1553.(IF 2009=2.465, 中科院小类分区=2区)
研究课题
1.项目负责人.广州市基础与应用基础研究专题科技菁英“领航”方向项目.中间普氏菌外膜囊泡促进巨噬细胞Necroptosis释放IL-17D调控牙髓细胞内质网应激参与牙髓炎发生及机制研究. 课题直接经费:30万元.起止时间:2024.4-2027.3
2.项目负责人.南方医科大学口腔医院临床研究启动计划.开窗根尖切除一体化导板辅助下显微镜根尖手术效果的多中心、前瞻性临床探究.课题编号:KQIIT2021002.课题直接经费:40万.起止时间:2021.10-2026.10
3.项目负责人.南方医科大学口腔医院.成牙本质细胞外泌体调节牙髓干细胞分化与牙髓炎修复及其机制研究.课题编号:PY2021001.课题直接经费:20万.起止时间:2021.02-2025.01
4.项目负责人(1/7). 国家自然科学基金(面上项目). 课题名称: 成牙本质细胞外泌体调节牙髓干细胞分化与牙髓炎修复及其机制研究. 课题编号: 81970930. 课题直接经费: 55万. 起止时间: 2020.01-2023.12
5.项目负责人(1/7). 国家自然科学基金(青年项目). 课题名称: Stathmin在人牙髓干细胞成牙本质向分化过程中的作用及分子机制研究. 课题编号: 81400495. 课题直接经费: 23万. 起止时间: 2015.01-2017.12
6.项目负责人(1/7). 广东省自然科学基金(博士启动项目). 课题名称: Stathmin调控Shh信号通路促进牙髓干细胞成牙本质向分化的作用机制研究.课题编号:2015A3030310101.课题直接经费:10万.起止时间:2015.08-2018.08
7.课题负责人(1/5).广东省口腔医学重点实验室开放课题. 课题名称:Shh信号通路在Stathmin调控牙髓干细胞成牙本质向分化的作用研究. 课题直接经费:2万. 起止时间:2016.01-2017.09
8.课题负责人(1/7).南方医科大学科研启动计划.课题名称:人深龋牙髓干细胞蛋白组学分析及矿化相关基因Stathmin功能及分子机制的研究. 课题直接经费:3万. 起止时间:2012.11-2014.10
9.课题负责人(1/6).南方医科大学南方医院院长基金.课题名称:炎症微环境Stathmin通过Wnt信号通路调控牙髓干细胞分化与修复的作用及机制研究.课题编号:2018B005,课题直接经费:5万. 起止时间:2019.01-2021.12
10.课题组成员(3/8).国家自然科学基金(面上项目).课题名称:晶界偏析对不同氧化物掺杂牙科氧化锆低温时效效应的影响.课题编号: 51672122.课题直接经费:62万.起止时间: 2017.01-2020.12
11.合作单位负责人(2/8).海南省重点研发计划项目.课题名称:炎症微环境下Stathmin调控牙髓干细胞成牙本质向分化与修复中的作用及机制研究.课题编号:ZDYF2019216.课题直接经费:40万.起止时间:2019.01-2021.12
12.合作单位负责人(2/8).海南省重点研发计划项目.课题名称:mTORC1信号通路调节成牙本质细胞外泌体对牙髓干细胞分化的影响及机制研究.课题编号:ZDYF2022SHFZ017.课题直接经费:30万.起止时间:2022.03-2024.03