杨平珍
教授、学术型博导
心血管内科主任/专业技术二级岗专家/主任医师
学术地位：
中国医师协会心律学专业委员会常委、中华医学会心电生理与起搏分会委员、粤港澳大湾区心脏协会副理事长、粤港澳大湾区心脏协会心律学专业委员会主任委员、广东省医学会心电生理与起搏分会主任委员、广东省医学会心血管病分会副主任委员、广东省房颤联盟主席、广东省胸痛协会副理事长。
课题基金：
1.国家自然科学基金委员会，面上项目，82370237;
2.国家自然科学基金委员会，面上项目，82070247;
3.广州地区临床重大技术项目，2024PL-ZD050，超高密度三维标测技术在ECMO辅助下对器质性室速的治疗，
4.广东省基础与应用基础研究基金委员会，面上项目， eEF2K通过AMPK介导促进自噬减轻阿霉素诱导的心肌损伤的作用及机制研究；
5.广东省基础与应用基础研究基金委员会，面上项目，2019A1515010899，AOC3对心梗后心肌纤维化的影响及其机制研究；
6.广东省基础与应用基础研究基金委员会，面上项目，2022A1515012263，TMAO对球囊损伤后血管新生内膜增生的影响及机制研究；
7.广东省教育厅，高水平大学建设经费南方医科大学临床研究启动项目，LC2016ZD022，两种不同消融策略治疗阵发性心房颤动的对比研究；
8.广东省科学技术厅，社会发展领域项目，2014A020212191，胰岛素调控自噬在心肌缺血再灌注过程中的作用及机制研究；
9.广东省科学技术厅，社会发展领域科技计划项目，2013B021800323，致心律失常性右室心肌病易感基因Plakophilin-2基因与室性心律失常的关系。
Guan, J., H. Mo, V. Virak, R. Guo, D. Que, W. Yu, X. Zhang, J. Yan, Y. Wang, Y. Yang, B. Rui, G. Huang, D. Chen, C. Zhong, and P. Yang, eEF2K alleviates doxorubicin-induced cardiotoxicity by inhibiting GSK3β and improving autophagy dysfunction. Cell Biol Toxicol, 2024. 41(1): p. 15.
Liao, X., M. Tang, J. Li, R. Guo, C. Zhong, X. Chen, X. Zhang, H. Mo, D. Que, W. Yu, X. Song, H. Li, Y. Cai, and P. Yang, Acid-Triggered Cascaded Responsive Supramolecular Peptide Alleviates Myocardial Ischemia‒Reperfusion Injury by Restoring Redox Homeostasis and Protecting Mitochondrial Function. Adv Healthc Mater, 2025: p. e2404319.
Wu, A., C. Zhong, X. Song, W. Yuan, M. Tang, T. Shu, H. Huang, P. Yang, and Q. Liu, The activation of LBH-CRYAB signaling promotes cardiac protection against I/R injury by inhibiting apoptosis and ferroptosis. iScience, 2024. 27(5): p. 109510.
Zhu, Y., D. Que, Z. Jin, X. Zhang, X. Song, K. Chen, and P. Yang, Association of different emotional support status with cardio-cerebrovascular diseases. J Affect Disord, 2025. 374: p. 303-311.
Hao, Q. Y., J. Yan, J. T. Wei, Y. H. Zeng, L. Y. Feng, D. D. Que, S. C. Li, J. B. Guo, Y. Fan, Y. F. Ding, X. L. Zhang, P. Z. Yang, J. W. Gao, and Z. H. Li, Prevotella copri promotes vascular calcification via lipopolysaccharide through activation of NF-κB signaling pathway. Gut Microbes, 2024. 16(1): p. 2351532.
Chongbin Zhong; Dongdong Que; Wenjie Yu; Deshu Chen; Yuxi Wang; Xuwei Zhang; Bowen Rui; Yashu Yang; Qingqing Hong; Guanlin Huan; Li Yang*; Jing Yan*; Pingzhen Yang*; Amine oxidase copper-containing 3 aggravates cardiac remodelling by generating hydrogen peroxide after myocardial infarction, Journal of Pathology, 2023, Feb 24, online ahead of print. doi: 10.1002/path.6075.
Deshu Chen; Wenjie Yu; Chongbin Zhong; Qingqing Hong; Guanlin Huang; Dongdong Que; Yuxi Wang; Yashu Yang; Bowen Rui; Zhenyu Zhuang; Miaoyuan Liang; Zhicheng Ye; Xin Yan; Jiankun Lv; Ronghua Zhang; Jing Yan*; Pingzhen Yang*; Elabela ameliorates doxorubicin-induced cardiotoxicity by promoting autophagic flux through TFEB pathway, Pharmacological Research, 2022, 178: 106186.
Qingqing Hong; Dongdong Que; Chongbin Zhong; Guanlin Huang; Weicheng Zhai; Deshu Chen; Jing Yan*; Pingzhen Yang*; Trimethylamine-N-oxide (TMAO) promotes balloon injury-induced neointimal hyperplasia via upregulating Beclin1 and impairing autophagic flux., Biomedicine & Pharmacotherapy, 2022, 155: 113639.
Huajun Zheng; Weicheng Zhai; Chongbin Zhong; Qingqing Hong; Hekai Li; Bowen Rui; Xingxing Zhu; Dongdong Que; Liyun Feng; Bin Yu; Guanlin Huang; Jianlong Yin; Jiacheng Li; Jing Yan*; Pingzhen Yang*; Nkx2-3 induces autophagy inhibiting proliferation and migration of vascular smooth muscle cells via AMPK/mTOR signaling pathway, Journal of Cellular Physiology, 2021, 236(11): 7342-7355.
Zheng Jin; Huanyi Zhao; Yuan Luo; Xiushen Li; Jiayan Cui; Jing Yan*; Pingzhen Yang*; Identification of core genes associated with the anti-atherosclerotic effects of Salvianolic acid B and immune cell infiltration characteristics using bioinformatics analysis, BMC Complementary Medicine and Therapies, 2022, 22(1).
Jing Yan; Jianyun Yan; Yuxi Wang; Yuanna Ling; Xudong Song; Siyi Wang; Haiqiong Liu; Qicai Liu; Ya Zhang; Pingzhen Yang*; Xianbao Wang*; Aihua Chen*; Spermidine-enhanced autophagic flux improves cardiac dysfunction following myocardial infarction by targeting the AMPK/mTOR signalling pathway, British Journal of Pharmacology, 2019, 176(17): 3126-3142.
Xiuli Zhang ; Yining Li; Pingzhen Yang; Xiaoyu Liu; Lihe Lu; Yanting Chen; Xinglong Zhong; Zehua Li; Hailin Liu; Caiwen Ou; Jianyun Yan*; Minsheng Chen*; Trimethylamine-N-Oxide Promotes Vascular Calcification Through Activation of NLRP3 (Nucleotide-Binding Domain, Leucine-Rich-Containing Family, Pyrin Domain-Containing-3) Inflammasome and NF-kappaB (Nuclear Factor kappaB) Signals., Arteriosclerosis, Thrombosis, and Vascular Biology, 2020, 40(3): 751-765.
Xu Liao; Xudong Song; Jiejing Li; Lisha Li; Xianglin Fan; Qin Qin; Chongbin Zhong; Pingzhen Yang*; Jie Zhan*; Yanbin Cai*; An injectable co-assembled hydrogel blocks reactive oxygen species and inflammation cycle resisting myocardial ischemia-reperfusion injury., Acta Biomaterialia, 2022, 149: 82.