一、主持或参加科研项目（课题）及人才计划项目情况（按时间倒序排序）：
项目类别、批准号、名称、研究起止年月、获资助金额、项目状态（已结题或在研等）、主持或参加。
1. 国家自然科学基金委员会，面上项目，82272364，弓形虫顶质体膜蛋白FtsH1参与虫体脂代谢及免疫逃避的机制研究，2023.01-2027.12，52.0万元，在研，主持
2. 国家自然科学基金委员会，面上项目，81971954，弓形虫DNA甲基转移酶在速/缓殖子相互转化过程中的作用机制研究，2020.01-2023.12，55.0万元，在研，主持
3. 广州市科技局，科学研究计划重点项目，201904020011，弓形虫ROP18劫持宿主细胞泛素系统实现免疫逃避机制的研究，2019.04-2022.03，200万元，在研，主持
4. 广东省科技厅，国际科技合作，2018A050506038，应用BioID方法筛选弓形虫毒力因子ROP18的互作蛋白组解析其抑制凋亡发生的机制，2018.12-2020.12，50万元, 在研，主持
5. 国家自然科学基金委员会，面上项目，81772217，弓形虫ROP18结合宿主NMI抑制IFN‐γ依赖抗感染机制的研究，2018.01-2021.12，55.0万元，结题，主持
6. 国家科技部，重点研发专项，2017YFD0500400，子课题“畜禽重要胞内寄生原虫的寄生与免疫机制研究”， 2017.07-2021.07， 70.0万元，在研，主持
7. 国家自然科学基金委员会，海外及港澳学者合作研究，8182800002，弓形虫ROP18在宿主生理活性下的互作蛋白组筛选及其调控宿主细胞凋亡机制的研究，2019.01-2020.12, 18.0万元，在研，与新加坡国立大学Cynthia Y. He合作主持
8. 广州市科技局，健康医疗协同创新重大专项（201604020011）分题，“新发突发烈性传染病防控及治疗新技术研究”, 2016.08-2018.08, 108.0万元, 已结题，唐时幸/彭鸿娟 主持
9. 国家自然科学基金委员会，面上项目，81572012，宿主细胞互作蛋白介导的弓形虫ROP18毒力机制研究, 2016.1-2019.12，55.0万元，已结题，主持
10. 广东省科技厅，自然科学基金重点项目，2016A030311025，宿主细胞互作蛋白介导的弓形虫ROP18毒力机制研究，2016.06-2019.05，30.0万元，已结题，主持
11. 广东省教育厅，珠江学者（特聘教授），2014年，流行病与统计学—传染病预防与控制, 2016.06-2019.05，100万元，已结题，主持
12. 国家自然科学基金委员会，面上项目，81271866，宿主细胞信号水平弓形虫感染机制的研究， 2013.1-2016.12，70.0万元，已结题，主持
13. 广东省教育厅，广东省高等学校人才引进专项资金（2011-67），弓形虫感染与宿主细胞信号转导的变化，2012.01-2014.12, 25.0万元，已结题，主持
14. 广东省科技厅，科技攻关项目，2011B010500003，一种高效安全重组蚊虫真菌杀虫剂的开发与应用，2012.01-2013.12，8.0万，已结题，主持
15. 国家自然科学基金委员会，面上项目，81071377，宿主细胞RacGTP酶及其相关信号通路在弓形虫入侵过程中的作用机制研究，2011.01-2013.12，32.0万元，已结题，主持
16. 广东省卫生厅，2011-2014年全国农村卫生环境监测横向课题，K1051022，2011.01-2014.12, 100.0万元，已结题，主持
17. 国家自然科学基金委员会，重点项目，31030066，弓形虫机会性致病的调控机制研究, 2011.1-2014.12, 212.0万元，已结题，参与
18. 国家教育部，高等学校博士学科专项科研基金，20104433120014，宿主细胞RacGTP酶参与弓形虫入侵宿主机制的研究，2011.01-2013.01，3.6万元，已结题，主持
19. 广东省科技厅，自然科学基金面上项目，A2010356，宿主细胞RacGTP酶参与弓形虫入侵宿主机制的研究，2011.09-2013.09， 5.0万，已结题，主持
20. 广东省科技厅，自然科学基金面上项目，06301141，日本血吸虫排泄分泌抗原蛋白质组学的研究， 2007.10-2009.10， 3.0万元，已结题，主持
21. 国家自然科学基金委员会，面上项目，30471503，以卫生害虫蜕皮激素受体为靶标的杀虫剂筛选模型的建立及应用，2005.01-2007.12，21.0万元，已结题，主持
22. 国家自然科学基金委员会，青年基金，30200240，日本血吸虫雌虫消减文库的构建及雌性特异基因筛选，2003.01-2005.12，19.0万元，已结题，主持
23. 世界卫生组织热带病防治规划署，培训项目，A00690, “The construction of Schistosoma japonicum cercaria cDAN library and identification of novel genes”, 8.0万元，2001.01-2003.12，已结题，主持
二、代表性研究成果和学术奖励情况（每项均按时间倒序排序）
期刊论文（第一作者论文）2022年总IF 212.4， 其中IF>10 文章4篇。
1． Peng H-J#,Henkels KM#, Mahankali M, Dinauer MC. Gomez-Cambronero J (2011) Evidence For Two Crib Domains In Phospholipase D2 (Pld2) That The Enzyme Uses to Specifically Bind to The Small GTPase Rac2. J Bio.Chem. 286(18): 16308-20 IF5.486
2． Peng H-J#, Henkels KM#, Mahankali M, Marchal C, Bubulya P, Dinauer MC, Gomez-Cambronero J (2011) The dual effect of Rac2 on phospholipase D2 regulation that explains both the onset and termination of chemotaxis. Mol Cell Biol. 31(11):2227-40. IF5.069
3． Peng H-J#，Chen X-G#，Lindsay DS*，A Review: Competence, Compromise, And Concomitance-Reaction Of The Host Cell To Toxoplasma Gondii Infection And Development. J Parasitol，2011.8.01，97（4）：620~628 IF1.434
4． Peng H-J#，Zhang C(#)，Wang C-M，Chen X-G*，Current Status and Challenge of Human Parasitology Teaching in China. Pathog Glob Health，2012.12.11，106（7）：386~390 IF3.735
5． Peng H-J，Lai H-B，Zhang Q-L，Xu B-Y，Zhang H，Liu W-H，Zhao W，Zhou Y-P，Zhong X-G，Jiang S，Duan J-H，Yan G-Y，He J-F(*)，Chen, Xiao-Guang，A local outbreak of dengue caused by an imported case in Dongguan China. BMC Public Health，2012.1.26，12（1）:83 IF4.134
（通讯作者论文）
6． Chen M #, Yao L #, Zhou L, Yang P, Zou W, Xu L, Li S, Peng HJ*. Toxoplasma gondii ROP18I Inhibits Host Innate Immunity through cGAS-STING Signaling. The FASEB Journal. 2022 Feb;36(2):e22171. doi: 10.1096/fj.202101347R. PMID: 35084749. IF5.5834
7． Zhou LJ, Peng J, Chen M, Yao LJ, Zou WH, He CY, Peng HJ*. Toxoplasma gondii SAG1 targeting host cell S100A6 for parasite invasion and host immunity. iScience. 2021 Nov 26;24(12):103514. doi: 10.1016/j.isci.2021.103514. PMID: 34950858; PMCID: PMC8671940. IF6.107
8． Xu L, Yao L, Jiang D, Zhou L, Chen M , Liao W, Zou W, Peng H*. A uracil auxotroph Toxoplasma gondii exerting immunomodulation to inhibit breast cancer growth and metastasis. Parasites & Vectors. 2021 Dec 11;14(1):601. DOI: 10.1186/s13071-021-05032-6 IF4.047
9． Jiang D, Wu S; Xu L, Xie G, Peng H*. Anti-Infection Roles of mir155-5p Packaged in Exosomes Secreted by Dendritic Cells Infected with Toxoplasma gondii. Parasites & Vectors.Parasites Vectors. 2022 Jan 6;15(1):3. DOI: 10.1186/s13071-021-05003-x IF4.047
10． Yao LJ, Xu LQ, Zhou LJ, Wu SZ, Zou WH, Chen M, Chen JT, Peng HJ*. Toxoplasma gondii Type-I ROP18 Targeting Human E3 Ligase TRIM21for Immune Escape. Front. Cell Dev. Biol.2021, May 26; 9:685913. doi: 10.3389/fcell.2021.685913. IF6.081
11． Kong L, Peng H*. Current epidemic situation of human toxocariasis in China.Adv Parasitol. 2020;109:433-448. doi: 10.1016/bs.apar.2020.01.016. Epub 2020 Feb 5. PMID: 32381211. IF10.528
12． Kong L#, Jiang D#, He C, Xia J, Wei H, Zhou L, Peng H*.TgROP18 targets IL20RB for host-defense-related-STAT3 activation during Toxoplasma gondii infection.Parasit Vectors. 2020 Aug 7;13(1):400. doi: 10.1186/s13071-020-04251-7. PMID: 32767999; PMCID: PMC7412674. IF4.047 JCR 一区
13． Xia J, Blank ML, Zhou LJ, Wu SZ, Peng HJ*, Boyle JP*. Strain-specific disruption of interferon-stimulated N-myc and STAT interactor (NMI) function by Toxoplasma gondii type I ROP18 in human cells. Parasitology. 2020 Nov;147(13):1433-1442. doi: 10.1017/S0031182020001249. Epub 2020 Jul 30. PMID: 32729455. IF 3.243 JCR 二区
14． He C，Xu MZ， Pan S，Wang H， Peng HJ*，Liu ZZ *. iTRAQ-Based Phosphoproteomic Analysis of Toxoplasma gondii Tachyzoites Provides Insight Into the Role of Phosphorylation for its Invasion and Egress. Frontiers in Cellular and Infection Microbiology, 2020 Nov 26;10:586466. doi: 10.3389/fcimb.2020.586466. PMID: 33363051; PMCID: PMC7756149. IF6.073
15． Deng SQ, Peng HJ*. Characteristics of and Public Health Responses to the Coronavirus Disease 2019 Outbreak in China. Journal of Clinical Medicine. J Clin Med. 2020 Feb 20;9(2):575. doi: 10.3390/jcm9020575. PMID: 32093211; PMCID: PMC7074453. IF4.964
16． Deng SQ, Yang X, Wei Y, Chen JT, Wang XJ, Peng HJ*. A Review on Dengue Vaccine Development.Vaccines. 2020 Feb 2;8(1):63. doi: 10.3390/vaccines8010063. IF4.961
17． Xia J, Kong L, Zhou LJ, Wu SZ, Yao LJ, He C, He CY, Peng HJ*. Genome-Wide Bimolecular Fluorescence Complementation- Based Proteomic Analysis of Toxoplasma gondii ROP18’s Human Interactome Shows Its Key Role in Regulation of Cell Immunity and Apoptosis. Front. Immunol. 2018 Feb 5;9:61. doi: 10.3389/fimmu.2018.00061. PMID: 29459857; PMCID: PMC5807661. IF8.786
18． Wu S#, Wei H#, Jiang D, Li S, Zou W, Peng HJ* . Genome-Wide CRISPR Screen Identifies Host Factors Required by Toxoplasma gondii Infection. Frontiers in Cellular and Infection Microbiology, 2020 Jan 22;9:460. doi: 10.3389/fcimb.2019.00460. PMID: 32039045; PMCID: PMC6987080. IF6.073
19． Li DL, Zou WH, Deng SQ, Peng HJ*. Analysis of the Dierential Exosomal miRNAs of DC2.4 Dendritic Cells Induced by Toxoplasma gondii Infection. Int. J. Mol. Sci. 2019 Nov 5; 20(21): 5506. doi: 10.3390/ijms20215506. PMID: 31694199; PMCID: PMC6862309. IF6.208
20． Wei H, Zhou L, Wu S, Li D, Deng S, Peng H*. Host cell Rac1 GTPase facilitates Toxoplasma gondii invasion. Sci China Life Sci. 2020 Apr; 63(4):610-612. doi: 10.1007/s11427-019-9564-0. Epub 2019 Jun 17. PMID: 31222548. IF10.372
21． Zhou LJ, Chen M, Puthiyakunnon S, He C, Xia J, He C, Deng SQ，Peng H*. Toxoplasma gondii ROP18 inhibits human glioblastoma cell apoptosis through a mitochondrial pathway by targeting host cell P2X1. Parasit Vectors. 2019 Jun 4;12(1):284. doi: 10.1186/s13071-019-3529-1. PMID: 31164145; PMCID: PMC6547611. IF4.047
22． He C, Kong L, Puthiyakunnon S, Wei HX, Zhou LJ, Peng H-J*. iTRAQ-based phosphoproteomic analysis reveals host cell's specific responses to Toxoplasma gondii at the phases of invasion and prior to egress. Biochim Biophys Acta Proteins Proteom. 2019 Mar;1867(3):202-212. doi: 10.1016/j.bbapap.2018.12.004. Epub 2018 Dec 18. PMID: 30576742. IF4.125
23． He C, Kong L, Zhou L, Xia J, Wei H, Liu M, Peng H* .Host Cell Vimentin Restrains Toxoplasma gondii Invasion and Its hosphorylation Is Partly Regulated by TgROP18 Interaction. Int J Biol Sci. 2017 Sep 5;13(9):1126-1137. doi: 10.7150/ijbs.21247. PMID: 29104504; PMCID: PMC5666328. IF10.75
24． Wei H, Jiang S, Chen L, He C, Wu S, Peng H*. Characterization of Cytosine Methylation and the DNA Methyltransferases of Toxoplasma gondii. Int J Biol Sci. 2017 Mar 11;13(4):458-470. doi: 10.7150/ijbs.18644. PMID: 28529454; PMCID: PMC5436566. IF10.75
25． He C, Chen AY, Feng XS, Wei HX, Jiang SC, Xia J, Deng SQ, Wang XJ, Peng HJ* Phosphoproteome of Toxoplasma gondii Infected Host Cells Reveals Specific Cellular Processes Predominating in Different Phases of Infection. Am J Trop Med Hyg. 2017 Jul;97(1):236-244. doi: 10.4269/ajtmh.16-0901. PMID: 28719319; PMCID: PMC5508905. IF3.707
26． Na RH, Zhu GH, Luo JX, Meng XJ, Cui L, Peng HJ*, Chen XG*, Gomez – Cambronero J. Enzymatically active Rho and Rac small-GTPases are involved in the establishment of the vacuolar membrane after Toxoplasma gondii invasion of host cells. BMC Microbiol. 2013 May 30;13:125. doi: 10.1186/1471-2180-13-125. PMID: 23721065; PMCID: PMC3681593. IF4.465
27． Xia J, Cheng XY, Wang XJ, Peng HJ* Association between Toxoplasma gondii types and outcomes of human infection: a review and meta-analysis. Acta Microbiologica et Immunologica Hungarica. 2017 Sep 1;64(3):229-244. doi: 10.1556/030.64.2017.016. Epub 2017 Jun 20. PMID: 28629230. IF2.298
28． Deng SQ, Zou WH, Li DL, Chen JT, Huang Q, Zhou LJ, Tian XX, Chen YJ, Peng HJ*. Expression of Bacillus thuringiensis toxin Cyt2Ba in the entomopathogenic fungus Beauveria bassiana increases its virulence towards Aedes mosquitoes. PLoS Negl Trop Dis. 2019 Jul 15;13(7):e0007590. doi: 10.1371/journal.pntd.0007590. PMID: 31306427; PMCID: PMC6667155. IF4.781
29． Deng SQ, Chen JT, Li WW, Chen M, Peng HJ. Application of the Scorpion Neurotoxin AaIT against Insect Pests. Int J Mol Sci. 2019 Jul 15;20(14):3467. doi: 10.3390/ijms20143467. PMID: 31311095; PMCID: PMC6678123. IF10.75
30． Deng S, Huang Q, Wei H, Zhou L, Yao L, Li D, Wu S, Chen J, Peng H*. Beauveria bassiana infection reduces the vectorial capacity of Aedes albopictus for the Zika virus. Journal of Pest Science. 2019, 92（2）:781-789. IF5.742
31． Li XL, Wei HX, Zhang H, Peng HJ*, Lindsay DS*. A Meta Analysis on Risks of Adverse Pregnancy Outcomes in Toxoplasma gondii Infection. PLoS One. 2014 May 15;9(5):e97775. doi: 10.1371/journal.pone.0097775. PMID: 24830795; PMCID: PMC4022675. IF3.752
32． Wei HX, Wei SS, Lindsay DS*, Peng HJ*. A Systematic Review and Meta-Analysis of the Efficacy of Anti-Toxoplasma gondii Medicines in Humans. PLoS One. 2015 Sep 22;10(9):e0138204. doi: 10.1371/journal.pone.0138204. PMID: 26394212; PMCID: PMC4578932. IF3.752
33． Shen SQ, Wei HX, Fu YH, Zhang H, Mo QY, Wang XJ, Deng SQ, Zhao W, Liu Y, Feng XS, Chen W, Peng HJ*. Multiple Sources of Infection and Potential Endemic Characteristics of the Large Outbreak of Dengue in Guangdong in 2014. Scientific Reports. 2015 Nov 23;5:16913. doi: 10.1038/srep16913. PMID: 26593240; PMCID: PMC4655357. IF4.996
34． Zhou LJ，Xia J，Wei HX，Liu XJ，Peng HJ* Risk of drug resistance in Plasmodium falciparum malaria therapy-a systematic review and meta-analysis.Parasitol Res. 2017 Feb;116(2):781-788. doi: 10.1007/s00436-016-5353-2. Epub 2016 Dec 27. PMID: 28028628. IF2.382
35． Xia J, Jiang SC, Peng HJ*. Association between Liver Fluke Infection and Hepatobiliary Pathological Changes: A Systematic Review. PLOS one. 2015 Jul 17;10(7):e0132673. doi: 10.1371/journal.pone.0132673. PMID: 26186510; PMCID: PMC4506038. IF3.752
36． Wang XJ, Jiang SC, Wei HX, Deng SQ, He C, Peng HJ*. The Differential Expression and Possible Function of Long Noncoding RNAs in Liver Cells Infected by Dengue Virus.Am J Trop Med Hyg. 2017 Dec;97(6):1904-1912. doi: 10.4269/ajtmh.17-0307. Epub 2017 Sep 28. PMID: 29016307; PMCID: PMC5805055. IF3.707
37． Wang XJ, Wei HX, Jiang SC, He C, Xu XJ, Peng HJ*. Evaluation of aminotransferase abnormality in dengue patients: A meta analysis.Acta Trop. 2016 Apr;156:130-6. doi: 10.1016/j.actatropica.2015.12.013. Epub 2015 Dec 29. PMID: 26739659. IF3.22
38． Deng SQ, Cai QD, Deng MZ, Huang Q, Peng HJ*. Scorpion neurotoxin AaIT-expressing Beauveria bassiana enhances the virulence against Aedes albopictur mosquitoes. AMB Express. 2017 Dec;7(1):121. doi: 10.1186/s13568-017-0422-1. Epub 2017 Jun 9. PMID: 28605881; PMCID: PMC5466577. IF4.126
39． Huang Q, Hu L, Liao QB, Xia J, Wang QR, Peng HJ*. Spatiotemporal analysis of the malaria epidemic in mainland China, 2004-2014. Am J Trop Med Hyg. 2017 Aug;97(2):504-513. doi: 10.4269/ajtmh.16-0711. PMID: 28829728; PMCID: PMC5544075. IF3.707
40． Zhang H. He Z, Zeng W*, Peng HJ*. Roles of Interferons in Pregnant Women with Dengue Infection: Protective or Dangerous Factors.Canadian Journal of Infectious Diseases and Medical Microbiology, 17:1671607. 2017; 2017:1671607. doi: 10.1155/2017/1671607. Epub 2017 Sep 7. PMID: 29081814; PMCID: PMC5610849. IF2.585
三、 获得学术奖励
1. 彭鸿娟，刘全，袁子国，朱兴全，范泉水. 弓形虫病流行特征、致病机制与防治基础研究. 中华医学科技奖三等奖（2021.03）, 排名1.
2. 彭鸿娟，刘全，袁子国，朱兴全，范泉水，张秀香，王泽东、何成、魏海霞。弓形虫病流行特征、致病机制与防治基础研究. 广东省医学科技奖二等奖（2021.01），排名1
3. 日本血吸虫病新基因的发现鉴定、及优势抗原的筛选及应用，广东省科学技术奖三等奖（2005年5月），排名1.
4. 弓形虫主要表面抗原的基因克隆、表达及其在诊断和疫苗研制中的应用。广东省科学技术奖二等奖（2004年5月），排名9.
四、 专利/Patents:
1. 国家发明专利名称：一种生物杀虫剂筛选模型及其制备方法和应用；发明人：彭鸿娟，陈晓光，顾金保；专利号：ZL 2006 1 0122057.4；专利授权时间：2010.07；专利申请国：中国
2. 国家发明专利名称：一种毒杀蚊幼虫的双价重组球孢白僵菌及其制备方法；发明人：彭鸿娟、廖启彬, 等。专利号：201510176572X; 专利授权时间：2018.05；专利申请国：中国
3. 国家发明专利名称：鼠源弓形虫Ftsh1单克隆抗体及其应用; 发明人：彭鸿娟，邹伟浩，郑佳佳。 专利号：202210377381.X。