南方医科大学教授，博士生导师；广东省组织构建与检测重点实验室主任；南方医科大学第五附属医院副院长。中国解剖学会血管分会常务理事；中国医药生物技术协会纳米生物技术分会委员；广东省生物物理学会常务理事；广东省生物医学工程学会生物材料专业委员会副主任委员； 广东省精准医学学会肾脏病分会副主任委员，“中国临床解剖学杂志”编委。入选广东省特支计划百千万工程领军人才。主持国家自然科学基金项目8项。主持广东省科技计划重点项目2项（平台类）、广东省科技重大项目1项以及广州市重点项目1项。近5年来，以通讯作者身份在Nature Biomedical Enginering, Nature Communications, Advanced Materials, Advanced functional Materials，ACS Nano, Biomaterials, Bioactive materials, Small, Theranostics, Applied Materials Today, ACS AMI等国际主流期刊发表论文40余篇。研究领域主要为基于组织工程的心肌再生和修复。率先提出重建心肌导电微环境有利于促进心肌修复的原位组织工程策略（Nature Communications, 2023； Advanced Materials, 2023； Nature Biomedical Enginering, 2021；Adv Fun Mat，2020， 2016；ACS Nano 2019；Biomaterials, 2021； Bioactive materials, 2021；Theranostics 2018，2020; Applied materials today 2018; ACS AMI 2018）；同时探讨了导电微环境重建策略在其他组织再生中的作用机制（Adv Fun Mat 2018; Biomater Sci. 2017, RSC adv. 2017）。

主要从事组织工程研究, 研究方向主要包括心血管组织工程、肿瘤组织工程、骨组织工程以及细胞与生物材料的相互作用。

1. Zhang Jie#, Shen Si#, Lin Rurong#, Huang Jianxing, Pu Chunyi, Chen Pinger, Duan Qixiang, You Xintong, Xu Chengzhong, Yan Bing, Gao Xinrui, Shen Ziqi, Cai Liu, Qiu Xiaozhong(*), Hou Honghao(*). Highly Stretchable and Biocompatible Wrinkled Nanoclay-Composite Hydrogel With Enhanced Sensing Capability for Precise Detection of Myocardial Infarction. Advanced Materials. 2023 35(9)，2209497. IF=32.086
2. Yutong He, Qian Li, Pinger Chen, Qixiang Duan, Jiamian Zhan , Xiaohui Cai, Leyu Wang, Honghao Hou, Xiaozhong Qiu. A smart adhesive janus hydrogel for non-invasive cardiac repair and tissue adhesion prevention. Nature Communications, 2022, 13:7666.
3. Ruihong Xie, Peng Zhang, Liu Cai, Ranran Guo, Leyu Wang, Xiaozhong Qiu*, Ye Tian*.Tumor-specific cyclic amplification of oxidative stress by disulfide-loaded fluoropolymer nanogels. European Journal of Pharmaceutics and Biopharmaceutics, 2022, 180: 212-223.
4. Haien Guan, Jianing Liu, Dan Liu, Chengbin Ding, Jiamian Zhan, Xiaofang Hu, Peng Zhang, Leyu Wang, Qiaofeng Lan,* and Xiaozhong Qiu*. Elastic and Conductive Melanin/Poly(Vinyl Alcohol) Composite Hydrogel for Enhancing Repair Effffect on Myocardial Infarction. Macromol. Biosci. 2022, 2200223:1-15.
5. Xiaofang Hu, Peng Zhang, Jianing Liu, Haien Guan, Ruihong Xie, Liu Cai, Jiasong Guo, Leyu Wang, Ye Tian*，Xiaozhong Qiu*.A Self-Association Cross-Linked conductive zwitterionic hydrogel as a myocardial patch for restoring cardiac function.Chemical Engineering Journal. 446 (2022) 136988. IF=16.744
6. Huimin Zhou, Xuanyi Lu, Chao Du, Zijian Zhou,* Jie Feng, Zhiyu Liang, Yikai Xu,* Xiaozhong Qiu,* Zheyu Shen*. Cycloacceleration of reactive oxygen species generation based on exceedingly small magnetic iron oxide nanoparticles for tumor ferroptosis therapy. Small 2022, 18, 2202705. IF = 15.153.
7. Xuanyi Lu, Huimin Zhou, Zhiyu Liang, Jie Feng, Yudie Lu, Lin Huang, Xiaozhong Qiu,* Yikai Xu,* Zheyu Shen*. Biodegradable and biocompatible exceedingly small magnetic iron oxide nanoparticles for T1-weighted magnetic resonance imaging of tumors. J. Nanobiotechnol. 2022, 20, 350. IF = 9.429.
8. Jie Zhan, Xu Liao, Xianglin Fan, Jianwu Zhang, Hekai Li, Yanbin Cai*,Xiaozhong Qiu*. An injectable and conductive TEMPOL/polypyrrole integrated peptide co-assembly hydrogel promotes functional maturation of cardiomyocytes  for myocardial infarction repair. Composites Part B. 2022, 236, 109794. IF=11.322
9. Yuedan Li, Xiaozhong Qiu*. Bioelectricity-coupling patches for repairing impaired myocardium. Wiley Interdiscip Rev Nanomed Nanobiotechnol. 2022, e1787. doi: 10.1002/wnan.1787. IF=9.423
10. Ranran Guo, Peng Zhang, Jianing Liu, Ruihong Xie, Leyu Wang, Liu Cai, Xiaozhong Qiu*, Hongxun Sang*. NIR Responsive Injectable Nanocomposite Thermogel System Against Osteosarcoma Recurrence. Macromol. Rapid Commun. 2022, 2200255. IF=5.006.
11. Weida Zhuang , Genlan Ye, Jiachang Wu, Guofang Fang, Zhuofeng Ye, Guohua Lai，Xiaozhong Qiu*, Hongxun Sang*.A 3D-printed bioactive polycaprolactone scaffold assembled with core/shell microspheres as a sustained BMP2-releasing system for bone repair.Biomaterials Advances (Materials Science and Engineering: C) 133 (2022) 112619.  IF=8.457.
12. Weirong Xiong#, Xiaoxian Wang, Haien Guan, Fanxuan Kong, Zhaoming Xiao, Yihan Jing, Liu Cai, Honghao Hou, Xiaozhong Qiu,*  Leyu Wang*. A vascularized conductive elastic patch for the repair of infarcted myocardium through functional vascular anastomoses and electrical integration. Advanced Functional Materials, 2022, 32(19):2111273. IF=19.92
13. Leyu Wang^#, Yuqing Liu^#, Genlan Ye^#, Yutong He, Bingyun Li, Yezhi Guan, Baoyong Gong, Kibret Mequanint, Malcolm M. Q. Xing*, Xiaozhong Qiu*. Injectable and conductive cardiac patches repair infarcted myocardium in rats and minipigs. Nature Biomedical Engineering. 2021, 5(10): 1157-1173.IF=29.238
14. Xiaoping Song^#, Xiaorui Wang^#, Jie Zhang, Si Shen, Wenming Yin, Genlan Ye, Leyu Wang, Honghao Hou, Xiaozhong Qiu*. A tunable self-healing ionic hydrogel with microscopic homogeneous conductivity as a cardiac patch for myocardial infarction repair. Biomaterials, 2021, 273, 120811. IF=15.304
15. Heng Wu, Rui Zhang, Bianxiang Hu, Yutong He, Yuehang Zhang, Liu Cai, Leyu Wang, Guobao Wang*, Honghao Hou*, Xiaozhong Qiu*. A porous hydrogel scaffold mimicking the extracellular matrix with swim bladder derived collagen for renal tissue regeneration. Chinese Chemical Letters. 2021, 32(12):3940-3947.
16. Xiaohui Fang^#*, Wu Zhang^#, Jiewen Li, Chunli Lin, Zhennan Chen, Meng Zhang, Shihong Huang, Dunke Lu, Minggui Wan, and Xiaozhong Qiu*. Signal processing assisted Vernier effect in a single interferometer for sensitivity magnification. Optics Express, 2021, 29, 11570-11581. IF=3.833
17. Xiaoliang Zhao^#, Huiyong Xu^#,   Genlan Ye,  Chuangkun Li,  Leyu Wang*,  Fang Hu* and  Xiaozhong Qiu*. Temperature-activated PRP–cryogel for long-term osteogenesis of adipose-derived stem cells to promote bone repair. Materials. Chemistry Frontiers, 2021, 5, 396-405. IF=8.683
18. Yutong He^#, Honghao Hou^#, Shuqi Wang^#, Rurong Lin, Leyu Wang, Lei Yu, Xiaozhong Qiu*. From waste of marine culture to natural patch in cardiac tissue engineering. Bioactive Materials, 2021, 6, 2000-2010. IF=16.874
19. Zheyu Shen, Ting Liu, Zhen Yang, Zijian Zhou, Wei Tang, Wenpei Fan, Yijing Liu, Jing Mu, Ling Li, Vladimir I. Bregadze, Swadhin K. Mandal, Anna A. Druzina, Zhenni Wei, Xiaozhong Qiu*, Aiguo Wu*, Xiaoyuan Chen*. Small-sized gadolinium oxide based nanoparticles for high-efficiency theranostics of orthotopic glioblastoma. Biomaterials, 2020,235:119783.  IF=15.304
20. Wei Zhenni^#, Jiang Zhenqi, Pan Chunshu, Xia Jianbi, Xu Kaiwei, Xue Ting, Yuan Bo, Akakuru Ozioma Udochukwu, Zhu Chengjie, Zhang Guilong, Mao Zheng, Qiu Xiaozhong*, Wu Aiguo*, Shen Zheyu*. Ten-Gram-Scale Facile Synthesis of Organogadolinium Complex Nanoparticles for Tumor Diagnosis. Small, 2020, 16(11): 1906870. IF=15.153
21. Jiewen Li^#, Meng Zhang, Minggui Wan, Chunli Lin, Shihong Huang, Cuihong Liu, Qingping He, Xiaozhong Qiu*, Xiaohui Fang*. Ultrasensitive refractive index sensor based on enhanced Vernier effect through cascaded fiber core-offset pairs. Optics Express, 2020, 28(3): 4145-4155. IF=3.833
22. Genlan Ye#, Chuangkun Li#, Xiaoliang Zhao, Feng Wen, Leyu Wang*, Xiaozhong Qiu* A Humanized Cancer-Bone Metastasis Mouse Model Based on Silica Nanoparticles-Incorporated Human Demineralized Bone Matrix. J. Biomed. Nanotechnol. 2019, 15(12), 2363-2375. IF=3.641
23. Genlan Ye#, Zubiao Wen#, Feng Wen, Xiaoping Song, Leyu Wang, Chuangkun Li, Yutong He, Sugandha Prakash, Xiaozhong Qiu*. Mussel-inspired conductive Ti2C-cryogel promotes functional maturation of cardiomyocytes and enhances repair of myocardial infarction. Theranostics. 2020; 10(5):2047-2066. IF=11.6
24. Chen Song#, Xingying Zhang#, Leyu Wang*, Feng Wen, Kaige Xu, Weirong Xiong, Chuangkun Li, Bingyun Li, Quan Wang, Malcolm M. Q. Xing* and Xiaozhong Qiu*. An Injectable Conductive Three-Dimensional Elastic Network by Tangled Surgical-Suture Spring for Heart Repair. ACS Nano 2019, 13, 14122-14137. IF=18.024
25. Song X#, Mei J#, Ye G, Wang L, Ananth A, Yu L, Xiaozhong Qiu (*). In situ pPy-modification of chitosan porous membrane from mussel shell as a cardiac patch to repair myocardial infarction. Applied Materials Today. 2019, 15: 87-99.IF=8.663
26. Leyu Wang#, Xingying Zhang#, Yutong He, Ying Wang, Wen Zhong, Kibret Mequanint, Xiaozhong Qiu,* and Malcolm Xing*. Ultralight Conductive and Elastic Aerogel for Skeletal Muscle Atrophy Regeneration. Adv Funct Mater, 2019, 29(1): 1806200. IF=19.92
27. Xiaotong Wang#, Leyu Wang#, Qiang Wu, Feng Bao, Huangtian Yang*, Xiaozhong Qiu*, Jiang Chang*. Chitosan/Calcium Silicate Cardiac Patch Stimulates Cardiomyocyte Activity and Myocardial Performance after Infarction by Synergistic Effect of Bioactive Ions and Aligned Nanostructure. ACS Appl. Mater. Interfaces, 2019, 11(1): 1449-1468. IF=10.383
28. Yutong He#, Genlan Ye#, Chen Song, Chuangkun Li, Weirong Xiong, Lei Yu, Xiaozhong Qiu*, Leyu Wang*. Mussel-inspired conductive nanofibrous membranes repair myocardial infarction by enhancing cardiac function and revascularization. Theranostics. 2018; 8(18):5159-5177.  IF=11.6
29. Huiyong Xu#, Ge Zhang#, Kaige Xu, Leyu Wang, Lei Yu, Malcolm M.Q. Xing,Xiaozhong Qiu.Mussel-inspired dual-functional PEG hydrogel inducing mineralization and inhibiting infection in maxillary bone reconstruction. Materials Science & Engineering C.2018, 90:379-386.  IF=8.457
30. Bianxiang Hu#, Zhifeng Yang#,, Lei Yu, Wang Zhang, Xiang Li, Feng Wen, Malcolm M. Q. Xing, Xiaozhong Qiu(*), and Guobao Wang(*).3D Hypoxia Microenvironment Created by a Single Cell Layer-by-Layer Assembly Spheroid Demonstrates the Role of miR-382 and Cell Autophagy in Renal Fibrosis. J. Biomed. Nanotechnol. 14, 331–343 (2018). IF=3.641
31. Xiangling Ren^#, Jiejie Ge^#, Shuai Li^#, Haibo Shao, Xiaozhong Qiu, Fangqiong Tang, and Xianwei Meng .A Dual-Emission Nanohybrid of Gold Nanoclusters and Carbon Dots for Ratiometric Fluorescence Detection of Reactive Oxygen Species and Glucose. J. Biomed. Nanotechnol. 2017, 13(11): 1425–1434. IF=3.641
32. Song C^#, Wang L*^#, Ye G, Song X, He Y, Xiaozhong Qiu(*) .Residual Ammonium Persulfate in Nanoparticles Has Cytotoxic Effects on Cells through Epithelial-Mesenchymal Transition.Sci Rep. 2017,7(1):11769. doi: 10.1038/s41598-017-12328-0. IF=4.996.
33. Song X#, Mei J#, Zhang X, Wang L, Singh G, Xing MMQ(*), Xiaozhong Qiu(*),.Flexible and highly interconnected, multi-scale patterned chitosan porous membrane produced in situ from mussel shell to accelerate wound healing.Biomater Sci. 2017,5(6):1101-1111. IF=7.59
34. Ge Zhang^#, Xiaoping Song^#, Jie Mei, Genlan Ye, Leyu Wang, Lei Yu, Malcolm M. Q. Xing, Xiaozhong Qiu(*), A simple 3D cryogel co-culture system used to study the role of CAFs in EMT of MDA-MB-231 Cells. RSC Adv., 2017, 7, 17208–17216. IF=4.036
35. Xiangling Ren，Jiejie Ge, Xianwei Meng(*), Xiaozhong Qiu(*), Jun Ren, Fangqiong Tang. Sensitive detection of dopamine and quinone drugs based on the quenching of the fluorescence of carbon dots. Science Bulletin, 2016，61(20), pp 1615-1623. IF=20.577
36. Leyu Wang(#)， Junzi Jiang(#)，Wenxi Hua，Ali Darabi，Xiaoping Song，Chen Song， Wen Zhong，Malcolm Xing(*), Xiaozhong Qiu(*).Mussel-Inspired Conductive Cryogel as Cardiac Tissue Patch to Repair Myocardial Infarction by Migration of Conductive Nanoparticles. Advanced Functional Materials， 2016, 26, 4293–4305.  IF=19.92.
37. Lili Sang(#), Yuqing Liu(#), Wenxi Hua, Kaige Xu,  Guobao Wang,  Wen Zhong, Leyu Wang, Shuchai Xu, Malcolm Xing (*),Xiaozhong Qiu(*). Thermally sensitive conductive hydrogel using amphiphilic crosslinker self-assembled carbon nanotube to enhance neurite outgrowth and promote spinal cord regeneration. RSC Adv., 2016,6, 26341-26351. IF=4.036
38. Guobao Wang, Tingting Zhao, Leyu Wang, Bianxiang Hu, Ali Darabi, Jiansheng Lin, Malcolm Xing (*),Xiaozhong Qiu(*). Studying different binding and intracellular delivery efficiency of ssDNA -single-walled carbon nanotube and their effects on LC3-related autophagy in renal mesangial cells via miRNA-382. ACS Applied Materials & Interfaces. 2015 , 7(46):25733-40. IF=10.383
39. Jiejie Ge, Xiangling Ren,* Xiaozhong Qiu,* Haitang Shi, Xianwei Meng* and Fangqiong Tang. Fast synthesis of fluorescent SiO 2 @CdTe nanoparticles with reusability in detection of H₂O_2. Journal of Materials Chemistry B. 2015, 3, 6385—6390.IF=7.571
40. Guobao Wang(#)，Tingting ZHao(#)，Xiaoping Song(#)，Wen Zhong，Lei Yu，Wenxi Hua，Malcolm M. Q. Xing(*)，Xiaozhong Qiu(*). A 3-D multicellular tumor spheroid on ultrathin matrix coated single cancer cells provides a tumor microenvironment model to study epithelial-to-mesenchymal transitions. Polym. Chem.，2015，（6）：283-293. IF=5.364
41. Lin, Jiansheng(#)，Hua, Wenxi，Zhang, Yi，Li, Chenghua，Xue, Wei，Yin, Jian，Liu, Zonghua(*)，Qiu, Xiaozhong(*). Effect of poly(amidoamine) dendrimers on the structure and activity of immune molecules. Biochimica et Biophysica Acta: General Subjects. 2015，1850（2）：419-425. IF=4.117
42. Chen, Jun(#)，Qiu, Xiaozhong(#)，Wang, Leyu，Zhong, Wen，Kong, Jiming，Xing, Malcolm M. Q.(*). Free-Standing Cell Sheet Assembled with Ultrathin Extracellular Matrix as an Innovative Approach for Biomimetic Tissues. Advanced Functional Materials，2014，24（15）：2216-2223.IF=19.92
43. Chen, Jun(#)，Qiu, Xiaozhong(#)，Ouyang, Jun，Kong, Jiming，Zhong, Wen(*)，Xing, Malcolm M. Q.(*). pH and Reduction Dual-Sensitive Copolymeric Micelles for Intracellular Doxorubicin Delivery. Biomacromolecules，2011，12（10）：3601-3611.IF=6.978
44. Zhou, Jin(#)，Chen, Jun(#)，Sun, Hongyu(#)，Qiu, Xiaozhong(#)，Mou, Yongchao，Liu, Zhiqiang，Zhao, Yuwei，Li, Xia，Han, Yao，Duan, Cuimi，Tang, Rongyu，Wang, Chunlan，Zhong, Wen，Liu, Jie，Luo, Ying，Mengqiu Xing, Malcolm(*)，Wang, Changyong(*). Engineering the heart: evaluation of conductive nanomaterials for improving implant integration and cardiac function. Scientific Reports，2014，4：3733-3733.IF=4.996
45. Shi, Junbin(#)，Guobao, Wang(#)，Chen, Hongli，Zhong, Wen，Qiu, Xiaozhong(*)，Xing, Malcolm M. Q.(*). Schiff based injectable hydrogel for in situ pH-triggered delivery of doxorubicin for breast tumor treatment. Polymer Chemistry，2014，（5）：6180-6189.IF=5.364
46. Jiang, Xinglu(#)，Wang, Guobao，Liu, Ru，Wang, Yaling，Wang, Yongkui，Qiu, Xiaozhong(*)，Gao, Xueyun(*). RNase non-sensitive and endocytosis independent siRNA delivery system: delivery of siRNA into tumor cells and high efficiency induction of apoptosis. Nanoscale，2013，5（16）：7256-7264.IF=8.307.