南方医科大学深圳医院 临床医学创新中心学术带头人、深圳市病毒肿瘤学重点实验室主任、研究员、博士生导师、博士后合作导师、美国国立卫生研究院（NIH）访问研究员 。

       近年来，共获得国家自然基金项目中港联合项目1项、国家自然基金项目7项、深圳市医学研究专项资金项目1项、深圳市重点实验室项目1项、863子项目1项、深圳市学科布局项目1项等资助。共发表SCI论文100多篇，H指数>35，其中以第一和通讯作者在 Nature microbiology、J Exp Clin Cancer Res 、Advanced science、PLOS pathogens、JITC、J. pathology、Nature Communications、Oncogene、molecular cancer 等杂志发表论文40多篇。主要研究方向：1. EBV感染分子机制与转化应用；2. EBV与鼻咽癌发生发展分子机制与转化应用；3.外泌体制备与转化应用。

       现为国际转化医学协会（ISTM）会员联席主席、中国研究型医院学会病毒肿瘤学专业委员会主任委员、中国抗癌协会肿瘤标志物委员会鼻咽癌标志专家委员会副主任委员、中国工程院院士同行评审专家、国家自然科学基金生命科学部重大研究计划评审组二审专家、科技部重点研发项目二审专家、波兰科学与高等教育部国家科学中心（National Science Centre）NCN基金评审专家、香港食品卫生署 RFCID/ HHSRF基金和成果评审专家、广东省重点实验室和科技成果评审专家，并担任Journal of translational medicine 和 Frontiers in Molecular Biosciences 副编辑、Clinical & translational medicine编委、中国研究型医院杂志编委，等。

1. EBV感染分子机制与转化应用；

2. EBV与鼻咽癌发生发展分子机制与转化应用；

3.外泌体制备与转化应用。

1. Yinggui Yang1, 2 #, Tengteng Ding1, 2 #, Ying Cong1, 2 #, Xiaomin Luo1 #, Changlin Liu1, 2, Ting Gong1, Min Zhao4, Xichun Zheng1, Chenglin Li1, Yuanbin Zhang1, 2, Jiayi Zhou1, 2, Chuping Ni1, 2, Xueyu Zhang 1, 2, Tao Wu1, Ziliang Ji 1, Shaodong Yang 1, Qingchun Zhou1, Dinglan Wu1, 2 *, Xinqi Gong3 *, Qingyou Zheng 1 *, Xin Li 1, 2 *   Interferon-induced transmembrane protein-1 competitively blocks Ephrin receptor A2-mediated Epstein–Barr virus entry into epithelial cells. Nature microbiology, 2024, 正式接收（IF=28.3）（小类一区）
2. Yufei Long, Tuotuo Chong, Xiaoming Lyu, Lujia Chen, Xiaomin Luo, Oluwasijibomi Damola Faleti, Simin Deng, Fei Wang, Mingliang He, Zhipeng Qian, Hongli Zhao, Wenyan Zhou, Xia Guo*, Ceshi Chen* and Xin Li*    FOXD1-dependent RalA-ANXA2-Src complex promotes CTC formation in breast cancer.  J Exp Clin Cancer Res, 2022, 41:301 (IF=12.658）（小类一区） 
3. Xiaona Chen#, Yi Hao#, Yong Liu#, Sheng Zhong, Yuehua You, Keyi Ao, Tuotuo Chong, Xiaomin Luo, Minuo Yin, Ming Ye, Hui He, Anwei Lu, Jianjun Chen, Xin Li *, Jian Zhang*, Xia Guo*. NAT10/ac4C/FOXP1 promotes malignant progression and facilitates immunosuppression by reprogramming glycolytic metabolism in cervical cancer. Advanced Science, 2023 Nov;10(32):e2302705. （IF=15.1004）（小类1区 ）
4. Wing Chung Tang,Sai Wah Tsao,Gareth E Jones, Xiong Liu, Ming Han Tsai, Henri-Jacques Delecluse, Wei Dai, Chanping You, Jun Zhang, Shaina Chor Mei Huang, Manton Man-Hon Leung, Tengfei Liu, Yick Pang Ching, Honglin Chen, Kwok Wai Lo, Xin Li*, Chi Man Tsang* Latent Membrane Protein 1 and macrophage-derived TNFα synergistically activate and mobilize invadopodia to drive invasion of nasopharyngeal carcinoma. J Pathol, 2023 Feb 259(2):163-179 (IF=9.883)（小类一区)
5. Zhou, Jiayi; Pei, Xiaojuan; Yang, Yingui; Wang, Zhu; Gao, Weijie; Ye, Ran; Zhang, Xianton g; Liu, Jiangang; Liu, Zhuohao; Yang, Xinzhi; Tao, Jingli; Gu, Chunshan; Hu, Wei; Chan, Franky Lu eng; Li, Xin Li, Xin*; Mao, Jie*; Wu, Dinglan* Orphan nuclear receptor TLX promotes immunosuppression via its transcriptional activation of PD-L1 in glioma. Journal for immunotherapy of cancer , 2021, 9(4 ): 0-e001937 （IF=12.469）（小类一区）
6. Xu Yang, GengXi Cai, BoWei Han, ZhiWei Guo, YingSong Wu, Xiaoming Lyu, LiMin Huang, YuanBin Zhang, Xin Li*, GuoLin Ye* and XueXi Yang*. Association between the nucleosome footprint of plasma DNA and neoadjuvant chemotherapy response for breast cancer. npj Breast Cancer, 2021, 7(1):35 (IF=6.7)（小类一区）
7. Xiaoming Lyu, Jianguo Wang, Xia Guo, Gongfa Wu, Yang Jiao, Oluwasijibomi Damola Falet, Pengfei Liu, Tielian Liu, Yufei Long, Tuotuo Chong, Xu Yang, Jing Huang, Mingliang He, Chi Man TSANG, Sai Wah TSAO, Qian Wang, Qiang Jiang*, Xin Li*. EBV-miR-BART1-5P activates AMPK/mTOR/HIF1 pathway via a PTEN independent manner to promote glycolysis and angiogenesis in nasopharyngeal carcinoma. PLOS pathogens, 2018 14(12): e1007484.  (IF=6.16)  （小类一区）
8. Wang Y, Tong L, Wang J, Luo J, Tang J, Zhong L, Xiao Q, Niu W, Li J, Zhu J, Chen H, Li X*, Wang Y* cRGD-functionalized nanoparticles for combination therapy of anti-endothelium dependent vessels and anti-vasculogenicmimicry to inhibit the proliferation of ovarian cancer．Acta Biomaterialia  2019, 94：495-504 (IF=7.242) （小类一区）
9. Longmei Cai, Yanfen Ye, Qiang Jiang, Xiaoming Lyu, Yuxiang Chen, Jinbing Li, Cuncun Yuan, Shuang Wang, Tengfei Liu, Kaitai Yao, Ji-Liang Li*, Xin Li* Epstein-Barr virus-encoded microRNA BART1 induces tumour metastasis by regulating PTEN-dependent pathways in nasopharyngeal carcinoma. Nature communications,2015,6:7353 ( IF=11.47) （小类一区）
10. L-M Cai , X-M Lyu , W-Y Fang ,Y-F Ye, W-R Luo, Y-Y Lu, C-C Yuan, T-F Liu, E Wang, F-M Marincola, K-T Yao, H-B Cai*, Xin Li* EBV-miR-BART7-3p promotes the EMT and metastasis of nasopharyngeal carcinoma cells by suppressing the tumor suppressor PTEN. Oncogene, 2015, 34(17): 2156–66(IF=8.459) （小类一区）