凌莉，南方医科大学深圳医院神经内科主任医师，医学博士，博士研究生导师，博士后独立导师，深圳市高层次人才，宝安区高层次人才，长期从事缺血性脑血管病的基础和临床研究，近年主要研究方向为缺血性脑血管病的神经可塑性和表观遗传学、神经退行性疾病的基础研究。

教学成绩：承担大学本科生神经病学授课，作为导师已培养博士后1名、博士研究生5名和硕士研究生7名。

科研成绩：作为课题负责人，主持1项国家自然科学基金项目、4项广东省自然科学基金委项目和4项深圳市科创委基础研究项目和1项深圳市临床研究中心项目。以第一或通讯作者发表SCI论文23篇。

学术任职：中国老年保健医学研究会慢性病防治管理委员会委员、广东省医院协会神经内科专业委员会常务委员、广东省老年保健协会神经内科专业会常务委员、广东省老年保健协会抗衰老及神经调控专业委员会委员、广东省中西医结合学会卒中专业委员会委员、深圳市卒中学会理事。

长期从事脑梗死后可塑性的基础研究，在脑梗死后血管新生、神经再生及远隔损害方面取得了一些研究成果，近年致力于脑梗死的表观遗传学研究、缺血性脑血管疾病和神经退行性疾病的基础研究。

以第一或通讯作者发表的代表性SCI文章：

1. Deng Zihao; Li Yudi; Chi Wenjun; Zhang Wanzhou; Li Fangming*; Ling Li*. tRFAla-AGC-3-M8 attenuates neuroinflammation and neuronal damage in Alzheimer’s disease via the EphA7-ERK1/2-p70S6K signaling pathway. Alzheimer's Research & Therapy, 2025, 17 1.（1区TOP，IF=7.6）

2. Ouyang Wenhao; Zekang Deng; Yudi Li; Wenjun Chi; Zhenjun Huang; Chengyi Zhan; Min Li; Dongtao Wang*; Fangming Li*; Yajie Liu*; Li Ling*. Traditional Chinese medicine in cerebral infarction: Integrative strategies and future directions. Phytomedicine, 2025.（1区TOP，IF= 8.3）

3. Ouyang Wenhao; Chenjie Zhu; Yudi Li; Hong Huang; Fangming Li*; Li Ling*. Assessing the neurotoxic risks of triethyl citrate in daily environmental exposure using network toxicology and molecular docking. Ecotoxicol Environ Saf, 2025.（1区，IF=6.1）

4. Ouyang Wenhao; Zijia Lai; Hong Huang; Li Ling*. Machine learning-based identification of cuproptosis-related lncRNA biomarkers in diffuse large B-cell lymphoma. Cell Biol Toxicol, 2025.（1区，IF= 5.9）

5. Zhang Wensheng; Weifang Xing; Wen Lin; Yajie Liu; Xiongjun He; Yangchun Wen; Minzhen Zhu; Li Ling*; Jinzhao He*. Plasma D-dimer can predict all-cause mortality after mechanical thrombectomy of anterior circulation noncardioembolic acute cerebral infarction. Langenbecks Arch Surg, 2025.

6. Zhang Wensheng; Yajie Liu; Hongxing Zhou; Jie Li; Weifang Xing; Kaifeng Li; Yudi Li; Xiongjun He; Li Ling*; Jinzhao He*. Postoperative blood glucose increase can predict all-cause mortality within 3 months after successful interventional recanalization in patients with acute large vessel occlusion cerebral infarction. Diabetol Metab Syndr, 2025.

7. Zhang Wensheng; Jie Li; Hongxing Zhou; Weifang Xing; Kaifeng Li; Yudi Li; Jinzhao He; Xiongjun He*; Yajie Liu*; Li Ling*. The predictive value of admission blood glucose to serum albumin ratio for futile recanalization after successful interventional recanalization in acute cerebral infarction with large vessel occlusion. Front Neurol, 2025.

8. Zhang Wensheng; Weifang Xing; Jiyun Feng; Yangchun Wen; Xiaojing Zhong; Li Ling*; Jinzhao He*. Predictive Value of Plasma D-Dimer for Cerebral Herniation Post-Thrombectomy in Acute Ischemic Stroke Patients. Int J Gen Med, 2024.

9. Zhang Wensheng; Weifang Xing; Jie Li; Yudi Li; Xiongjun He; Yajie Liu; Jinzhao He*; Li Ling*. Failure of early neurological improvement can predict futile recanalization after successful interventional recanalization of anterior circulation tandem lesions. Clin Neurol Neurosurg, 2024.

10. Wan Keyu; Tiantian Nie; Wenhao Ouyang; Yunjing Xiong; Jing Bian; Ying Huang; Li Ling*; Zhenjun Huang*; Xianhua Zhu*. Exploring the impact of N4-acetylcytidine modification in RNA on non-neoplastic disease: unveiling its role in pathogenesis and therapeutic opportunities. Brief Funct Genomics, 2024.

11. Zhang Wensheng; Weifang Xing; Li Ling*. Tongue Edema Caused by Taking Nifedipine Controlled-Release Tablets. Neurol India, 2024.

12. Wang Yifan; Zhaofei Dong; Jie Li; Yudi Li; Jianyi Mai; Wenru Tan; Siqi Yang; Li Ling*; Yajie Liu*. Altered expression of circular RNA in patients with cervical artery dissection. Front Neurol, 2023.

13. Zhang Wensheng; Weifang Xing; Yunqiang Huang; JinZhao He*; Li Ling*. Human herpesvirus meningitis type 7 combined with neuromyelitis optica spectrum disorders: a case report. Acta Neurol Belg, 2023.

14. Zhang Wanzhou; Yudi Li; Fangming Li*; Li Ling*. Sphingosine-1-phosphate receptor modulators in stroke treatment. J Neurochem, 2022.

15. Li Yudi; Hanzhao Li; Yang Luo; Xiaoqiang Li; Zhefeng Chen; Wanzhou Zhang; Fangming Li*; Li Ling*. The Alteration Profiles of m(6)A-Tagged circRNAs in the Peri-Infarct Cortex After Cerebral Ischemia in Mice. Front Neurosci, 2022.

16. Zhong Yulan; Xiaoqiang Li; Chuqiao Li; Yudi Li; Yuqi He; Fangming Li*; Li Ling*. Intracerebral hemorrhage alters circular RNA expression profiles in the rat brain. Am J Transl Res, 2020.

17. Li Fangming; Chuqiao Li; Xiaoqiang Li; Yudi Li; Yulan Zhong; Li Ling*. Altered circular RNA expression profiles in the non-ischemic thalamus in focal cortical infarction mice. Aging (Albany NY), 2020.

18. Li Xiaoqiang; Fangming Li*; Li Ling*; Chuqiao Li; Yulan Zhong. Intranasal administration of nerve growth factor promotes angiogenesis via activation of PI3K/Akt signaling following cerebral infarction in rats. Am J Transl Res, 2019.

19. Li Xiaoqiang; Li Ling*; Chuqiao Li; Qiujie Ma. Efficacy and safety of desmoteplase in acute ischemic stroke patients: A systematic review and meta-analysis. Medicine (Baltimore), 2017.

20. Ling Li; Suping Zhang; Zhangge Ji; Huihong Huang; Gang Yao; Muzhen Wang; Rui He; Wanqing Deng; Li Fang. Therapeutic effects of lipo-prostaglandin E1 on angiogenesis and neurogenesis after ischemic stroke in rats. Int J Neurosci, 2015.

21. Ling Li; Jinsheng Zeng; Zhong Pei; Raymond TF Cheung; Qinghua Hou; Shihui Xing; Suping Zhang. Neurogenesis and angiogenesis within the ipsilateral thalamus with secondary damage after focal cortical infarction in hypertensive rats. J Cereb Blood Flow Metab, 2009.

22. Ling Li; Liangfu Zhu; Jinsheng Zeng; Songjie Liao; Suping Zhang; Jian Yu; Zhiyun Yang. Pontine infarction with pure motor hemiparesis or hemiplegia: a prospective study. BMC Neurol, 2009.

23. Ling Li; Qinghua Hou; Shihui Xing; Jian Yu; Zhong Pei; Jinsheng Zeng. Exogenous kallikrein enhances neurogenesis and angiogenesis in the subventricular zone and the peri-infarction region and improves neurological function after focal cortical infarction in hypertensive rats. Brain Res, 2008.

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