段传志

二级教授、主任医师、博士生（后）导师

广东省医学领军人物

首届广东省医师奖

首届珠江医师奖

脑科学与脑智能研究院 院长

《中华神经医学杂志》副总编辑

南方医科大学珠江医院脑血管病中心主任

教育部脑血管病诊疗技术与器械研发工程中心主任

中国医师协会神经介入专业委员会副主任委员

广东省医学会神经介入学分会主任委员

广东省医师协会神经介入医师分会首任主任委员

广东省脑科学应用协会副会长

国际血管联盟中国分部脑血管病委员会副主任委员

学术及奖项：

·发表科学论文数百篇，其中SCI论文100余篇，总影响因子超500

·主编专著三部《实用介入神经放射学》《颅内动脉瘤血管内治疗学》《颅内动静脉畸形血管内治疗学》

·编撰《中国颅内未破裂动脉瘤诊疗指南 2021》《中国颅内破裂动脉瘤诊疗指南 2021》等指南和专家共识10部

·先后获广东省科学技术一等奖1项，获省部级科技及医疗成果二等奖6项，三等奖7项，并于2009年获广东省第十届丁颖科技奖

·先后指导硕士博士生100余名，博士后16名

1.脑血管疾病的神经微创介入和显微外科治疗（临床研究）

2.蛛网膜下腔出血后早期脑损伤的机制研究（基础研究）

3.脑血管疾病发病机制研究（遗传学、血流动力学）

4.人工工程血管和颅骨修补材料的开发验证（材料学）

5.神经介入新型诊疗器械和技术的开发验证（细胞、分子、动物模型等）

5.脑血管疾病多模态专病数据库前瞻性队列研究（临床研究）

6.脑血管疾病的高分辨磁共振和4D-Flow影像组学研究（影像组学）

7.心脑血管疾病的生物信息学分析或公共数据流行病学研究（公共数据库）

   从事脑血管疾病的医教研工作三十余年，以第一作者/通讯作者（含共同通讯）在Gut、Stroke、J Nanobiotechnology、Redox Biology、Journal of Neuroinflammation、Cell Death Diseases、Journal of Neurointerventional Surgery、Journal of Neurosurgery、European Radiology等权威期刊发表SCI论文百余篇，其中中科院1区及2区SCI论文三十余篇，总影响因子超500分，其中代表论文如下：

    1. Sun H, Sun K, Tian H, Chen X, Su S, Tu Y, Chen S, Wang J, Peng M, Zeng M, Li X, Luo Y, Xie Y, Feng X, Li Z, Zhang X, Li X, Liu Y, Ye W, Chen Z, Zhu Z, Li Y, Xia F, Zhou H, Duan C(末尾通讯作者). Integrated metagenomic and metabolomic analysis reveals distinctive stage-specific gut-microbiome-derived metabolites in intracranial aneurysms. Gut. 2024 Sep 9;73(10):1662-1674. （中科院小类1区，IF=25.8）

    2. Yang Z, Jin L, Li L, Wu Y, Liu W, Feng X, Li L, Jin F, Bi Y, Li R, Guo S, Wang Y, Wei B, Liu Y, Li X, Duan C(末尾通讯作者). Brain targeted lipid nanoparticles with Hv1 inhibitors alleviate neuroinflammation post-ischemic stroke. J Nanobiotechnology. 2025 Jul 1;23(1):464.（中科院小类1区，IF=12.6）

    3. Xu A, Zhang N, Su S, Shi H, Lu D, Li X, Zhang X, Feng X, Wen Z, Ma G, Huang M, Huang C, Hu Y, Yuan H, Liu Q, Guan D, Wang J, Duan C(末尾通讯作者). A highly stretchable, adhesive, and antibacterial hydrogel with chitosan and tobramycin as dynamic cross-linkers for treating the infected diabetic wound. Carbohydr Polym. 2024 Jan 15;324:121543.（中科院小类1区，IF=12.5）

    4. Fan H, Tian H, Jin F, Zhang X, Su S, Liu Y, Wen Z, He X, Li X, Duan C(末尾通讯作者). CypD induced ROS output promotes intracranial aneurysm formation and rupture by 8-OHdG/NLRP3/MMP9 pathway. Redox Biol. 2023 Nov;67:102887.（中科院小类1区，IF=11.9）

    5. Fan H, Ding R, Liu W, Zhang X, Li R, Wei B, Su S, Jin F, Wei C, He X, Li X, Duan C(末尾通讯作者). Heat shock protein 22 modulates NRF1/TFAM-dependent mitochondrial biogenesis and DRP1-sparked mitochondrial apoptosis through AMPK-PGC1α signaling pathway to alleviate the early brain injury of subarachnoid hemorrhage in rats. Redox Biol. 2021 Apr;40:101856. （中科院小类1区，IF=11.9）

    6. Feng X, Huang C, Tong X, Wen Z, Zhu Y, Huang M, Lin J, Huang J, Yuan H, Xu A, Ma G, Ge R, Li C, Peng C, Su S, Zhang X, Li X, Guo Z, Liu A, Duan C(末尾通讯作者). Effect of LDL-Cholesterol Levels and Oral Atorvastatin on Outcomes After Pipeline Therapy for Intracranial Aneurysms. Stroke. 2025 Aug 6. doi: 10.1161/STROKEAHA.124.049833. （中科院小类1区，IF=8.9）

    7. Liu W, Li R, Yin J, Guo S, Chen Y, Fan H, Li G, Li Z, Li X, Zhang X, He X, Duan C(独立通讯作者). Mesenchymal stem cells alleviate the early brain injury of subarachnoid hemorrhage partly by suppression of Notch1-dependent neuroinflammation: involvement of Botch. J Neuroinflammation. 2019 Jan 15;16(1):8. （中科院小类1区，IF=10.1）

    8. Li R, Liu W, Yin J, Chen Y, Guo S, Fan H, Li X, Zhang X, He X, Duan C(独立通讯作者). TSG-6 attenuates inflammation-induced brain injury via modulation of microglial polarization in SAH rats through the SOCS3/STAT3 pathway. J Neuroinflammation. 2018 Aug 20;15(1):231.（中科院小类1区，IF=10.1）

    9. Chen M, Li X, Zhang X, He X, Lai L, Liu Y, Zhu G, Li W, Li H, Fang Q, Wang Z, Duan C(独立通讯作者). The inhibitory effect of mesenchymal stem cell on blood-brain barrier disruption following intracerebral hemorrhage in rats: contribution of TSG-6. J Neuroinflammation. 2015 Apr 1;12:61. （中科院小类1区，IF=10.1）

    10. Wei B, Liu W, Jin L, Huang Y, Cheng W, Fan H, Su S, Jin F, Zhang X, Yang Z, Liang S, Li L, Wu Y, Liu Y, Duan C(共同通讯作者), Li X. Hepcidin depending on astrocytic NEO1 ameliorates blood-brain barrier dysfunction after subarachnoid hemorrhage. Cell Death Dis. 2024 Aug 7;15(8):569. （中科院小类1区，IF=9.6）

    11. Yao ZQ, Zhang X, Zhen Y, He XY, Zhao S, Li XF, Yang B, Gao F, Guo FY, Fu L, Liu XZ, Duan CZ(末尾通讯作者). A novel small-molecule activator of Sirtuin-1 induces autophagic cell death/mitophagy as a potential therapeutic strategy in glioblastoma. Cell Death Dis. 2018 Jul 10;9(7):767. （中科院小类1区，IF=9.6）

    12. Wen Z, Feng X, Tong X, Peng C, Xu A, Fan H, Bi Y, Liu W, Li Z, Guo S, Jin F, Li R, Liu Y, Su S, Zhang X, Li X, He X, Liu A,  Duan C(末尾通讯作者). A Mendelian randomisation, propensity score matching study to investigate causal association between serum homocysteine and intracranial aneurysm. Stroke Vasc Neurol. 2024 Jun 21;9(3):202-211.（中科院小类1区，IF=5.9）

    13. Huang C, Ma G, Tong X, Feng X, Wen Z, Huang M, Xu A, Yuan H, Shi H, Lin J, Li C, Ge R, Huang J, Peng C, Zhu Y, Wang T, Huang C, Guo Z, Liang S, Su S, Zhang X, Li X, Liu A, Duan CZ(末尾通讯作者). Comparison of Pipeline embolization device versus Tubridge embolization device in unruptured intracranial aneurysms: a multicenter, propensity score matched study. J Neurointerv Surg. 2024 May 6;17(5):467-474. （中科院小类1区，IF=4.9）

    14. Duan CZ(第一作者), Huang C, Wen Z, Li YX, Huang M, Ma G, Li CH, Yuan H, Xu A, Shi H, Lin J, Li C, Huang J, Ge R, Bi Y, Qian Y, Su S, Zhang X, Li X, Wen Z, Feng X. Cross-sectional and longitudinal association of sleep patterns and aneurysmal vulnerability biomarkers on high-resolution magnetic resonance vessel wall imaging. J Neurointerv Surg. 2025 Jan 19:jnis-2024-022650. （中科院小类1区，IF=4.9）

   15. Feng X, Huang J, Weng S, Huang C, Huang M, Wen Z, Ge R, Li C, Lin J, Yuan H, Dai L, Chen W, Yi R, Xu A, Shi H, Jin Y, Deng X, Xie Z, Liang S, Bi Y, Su S, Zhang X, Li X, Ou C, Xiang J, Duan CZ(末尾通讯作者). J Neurointerv Surg. 2025 July. jnis-2025-023406（中科院小类1区，IF=4.9）

    16. Zhang M, Hou X, Qian Y, Chong W, Zhang X, Duan CZ(共同通讯作者), Ou C. Evaluation of aneurysm rupture risk based upon flowrate-independent hemodynamic parameters: a multi-center pilot study. J Neurointerv Surg. 2023 Jul;15(7):695-700. （中科院小类1区，IF=4.9）

    17. Li G, Yang T, Liu Y, Su H, Liu W, Fang D, Jin L, Jin F, Xu T, Duan C(末尾通讯作者). The proteins derived from platelet-rich plasma improve the endothelialization and vascularization of small diameter vascular grafts. Int J Biol Macromol. 2023 Jan 15;225:574-587.（中科院小类2区，IF=8.5）

    18. Yang T, Li G, Li X, Wei B, Su H, Liu W, Guo S, Yang N, Xu T, Duan C(末尾通讯作者). VEGF combined with DAPT promotes tissue regeneration and remodeling in vascular grafts. Regen Biomater. 2023 Oct 13;10:rbad088.（中科院小类2区，IF=8.1）

    19. Ding M, Jin L, Wei B, Cheng W, Liu W, Li X, Duan C(末尾通讯作者). Tumor necrosis factor-stimulated gene-6 ameliorates early brain injury after subarachnoid hemorrhage by suppressing NLRC4 inflammasome-mediated astrocyte pyroptosis. Neural Regen Res. 2024 May;19(5):1064-1071. （中科院小类2区，IF=6.7）

    20. Xu N, Li X, Weng J, Wei C, He Z, Doycheva DM, Lenahan C, Tang W, Zhou J, Liu Y, Xu Q, Liu Y, He X, Tang J, Zhang JH, Duan C(末尾通讯作者). Adiponectin Ameliorates GMH-Induced Brain Injury by Regulating Microglia M1/M2 Polarization Via AdipoR1/APPL1/AMPK/PPARγ Signaling Pathway in Neonatal Rats. Front Immunol. 2022 Jun 3;13:873382. （中科院小类2区，IF=5.9）

    21. Zhang X, Karuna T, Yao ZQ, Duan CZ(独立通讯作者), Wang XM, Jiang ST, Li XF, Yin JH, He XY, Guo SQ, Chen YC, Liu WC, Li R, Fan HY. High wall shear stress beyond a certain range in the parent artery could predict the risk of anterior communicating artery aneurysm rupture at follow-up. J Neurosurg. 2018 Sep 28;131(3):868-875. （中科院小类2区，IF=3.6）

    22. Zhang X, Yao ZQ, Karuna T, He XY, Wang XM, Li XF, Liu WC, Li R, Guo SQ, Chen YC, Li GC, Duan CZ(独立通讯作者). The role of wall shear stress in the parent artery as an independent variable in the formation status of anterior communicating artery aneurysms. Eur Radiol. 2019 Feb;29(2):689-698. （中科院小类2区，IF=4.7）

    23. Ou C, Li C, Qian Y, Duan CZ(共同通讯作者), Si W, Zhang X, Li X, Morgan M, Dou Q, Heng PA. Morphology-aware multi-source fusion-based intracranial aneurysms rupture prediction. Eur Radiol. 2022 Aug;32(8):5633-5641.（中科院小类2区，IF=4.7）

    24. Jin F, Jin L, Wei B, Li X, Li R, Liu W, Guo S, Fan H, Duan C(独立通讯作者). miR-96-5p alleviates cerebral ischemia-reperfusion injury in mice by inhibiting pyroptosis via downregulating caspase 1. Exp Neurol. 2024 Apr;374:114676. （中科院小类2区，IF=4.2）

    25. Chen JX, Lai LF, Zheng K, Li GX, He XY, Li LP, Duan CZ(末尾通讯作者). Influencing factors of immediate angiographic results in intracranial aneurysms patients after endovascular treatment. J Neurol. 2015 Sep;262(9):2115-23. （中科院小类2区，IF=4.6）

    26. Cheng W, Wei B, Liu W, Jin L, Guo S, Ding M, Liu Y, Fan H, Li R, Zhang X, He X, Li X, Duan C(末尾通讯作者). p97 inhibits integrated stress response-induced neuronal apoptosis after subarachnoid hemorrhage in mice by enhancing proteasome function. Exp Neurol. 2024 Jul;377:114778. （中科院小类2区，IF=4.2）

    27. Gu DQ, Zhang X, Luo B, Long XA, Duan CZ(末尾通讯作者). Impact of ultra-early coiling on clinical outcome after aneurysmal subarachnoid hemorrhage in elderly patients. Acad Radiol. 2012 Jan;19(1):3-7. （中科院小类2区，IF=3.9）

    28. Quan T, Zhang X, Li J, Wang Z, Fu X, Feng X, Xu H, Duan C(共同通讯作者), Guan S. Reconstructive Endovascular Treatment of Compensative-Flow-Related Posterior Circulation Aneurysms With Anterior Circulation Artery Occlusion. Neurosurgery. 2025 Mar 1;96(3):630-639.（中科院小类2区，IF=3.9）

    29. Jin F, Duan CZ(独立通讯作者). Identification of immune-infiltrated hub genes as potential biomarkers of Moyamoya disease by bioinformatics analysis. Orphanet J Rare Dis. 2022 Feb 23;17(1):80.（中科院小类2区，IF=3.5）

    30. Zhang X, Long XA, Luo B, Karuna T, Duan CZ(独立通讯作者). Factors responsible for poor outcome after intraprocedural rerupture of ruptured intracranial aneurysms: identification of risk factors, prevention and management on 18 cases. Eur J Radiol. 2012 Jan;81(1):e77-85. （中科院小类2区，IF=3.3）