目录
更新日期:2025年4月2日
姓 名 周凤华 性 别
民 族 汉族 导师层次 博士导师
技术职称 教授 导师类型 学术型
最后学历 博士研究生毕业 最后学位 医学博士学位
行政职务 Email wendyzhou515@126.com
工作单位 中医药学院 邮政编码 510515
个人简介

医学博士,副教授,博士生导师、博士后合作导师,美国Texas A & M University 访问学者,广东省中西医结合学会心血管病专业委员会常委,世界中医药联合会中医诊断专业委员会理事,中国中西医结合学会诊断专委会委员,广东省人口文化促进会企业家健康委员会秘书长,第七批全国老中医药专家学术经验继承人,贾钰华省名中医传承工作室主任。目前主要从事中医药防治缺血性心血管疾病及代谢病机制研究,主持国家及省市级科研项目10项,以第一或通讯作者发表科研论文45篇,SCI收录15篇,副主编专著1部,荣获广东省科技进步二等奖(排名第二)和中国中西医结合学会科学技术二等奖1项(排名第二)。

 

研究领域

1. 中医药防治缺血性心血管疾病研究;

2. 中医药调控糖脂代谢分子机制研究;

个人成果

SCI论文:

[1] Zhang Y, Zhang L, Li Z, Liu X, He P, Gu Y, Liu L, Jin Y, Cheng S*, Zhou F*, Jia Y*. Gualou-Xiebai-Banxia-Tang regulates liver-gut axis to ameliorate Metabolic Syndrome in HFD-fed mice. Phytomedicine. 2023 Dec 25. 

[2] Gu YY, Cui XB, Jiang J, Zhang YX, Liu MH, Cheng SB, Li YY, Liu LL, Liao RX, Zhao P, Jin W, Jia YH, Wang J, Zhou FH*. Dingxin recipe Ⅲ ameliorates hyperlipidemia injury in SD rats by improving the gut barrier, particularly the SCFAs/GPR43 pathway. J Ethnopharmacol. 2023 Aug 10;312:116483. PubMed PMID: 37059245.

[3] Zhang Y, Gu Y, Jiang J, Cui X, Cheng S, Liu L, Huang Z, Liao R, Zhao P, Yu J, Wang J, Jia Y, Jin W, Zhou F*. Stigmasterol attenuates hepatic steatosis in rats by strengthening the intestinal barrier and improving bile acid metabolism. NPJ Sci Food. 2022 Aug 27;6(1):38. pii: 10.1038/s41538-022-00156-0. doi: 10.1038/s41538-022-00156-0. PubMed PMID: 36030278.

[4] Huang K, Chen Y, Liang K, Xu X, Jiang J, Liu M, Zhou F*. Review of the Chemical Composition, Pharmacological Effects, Pharmacokinetics, and Quality Control of Boswellia carterii. Evid Based Complement Alternat Med. 2022;2022:6627104. doi: 10.1155/2022/6627104. PubMed PMID: 35069765.

[5] Zhang Y#, Qu S#, Zhang L#, Gu Y, Chen Y, Huang Z, Liu M, Zou W, Jiang J, Chen J*, Wang Y*, Zhou F*. The role of ophiopogonin D in atherosclerosis: impact on lipid metabolism and gut microbiota [J]. Am J Chin Med. 2021.Jul 14;1-19

[6] Gu Y#, Zhang Y#, Li M#, Huang Z, Jiang J, Chen Y, Chen J, Jia Y, Zhang L*, Zhou F*. Ferulic Acid Ameliorates Atherosclerotic Injury by Modulating Gut Microbiota and Lipid Metabolism [J]. Front Pharmacol. 2021. 12:621339

[7] Cui X, Huang Z, Lou L, Cheng S, Zhang Y, Zhang Y, Jia Y*, Zhou F*. Dingxin recipe alleviates atherosclerosis injury in ApoE-knockout mice via downregulation of visfatin expression and inhibition of the visfatin-induced inflammatory response [J]. J Tradit Chin Med. 2020. 40(6):938-946.

[8] Zhang Y#, Gu Y#, Chen Y, Huang Z, Li M, Jiang W, Chen J, Rao W, Luo S, Chen Y, Chen J, Li L, Jia Y*, Liu M*, Zhou F*. Dingxin Recipe IV attenuates atherosclerosis by regulating lipid metabolism through LXR-α/SREBP1 pathway and modulating the gut microbiota in ApoE-/- mice fed with HFD [J]. J Ethnopharmacol. 2020. 266:113436.

[9] Huang Z#, Tian G#, Cheng S, Zhao D, Zhang Y, Jia Y, Zhou F*. Polydatin Attenuates Atherosclerosis in ApoE -∕- Mice through PBEF Mediated Reduction of Cholesterol Deposition [J]. Am J Chin Med. 2018. 46(8):1841-1859.

[10] Zhou F, Jia Y, Ye S, Lou L, Yang P, Li J, Zhang Y, Qian R. A Chinese Compound Prescription Ding Xin Recipe Combined with Amiodarone for Treating Premature Ventricular Complexes: A Randomized, Double-Blind, Multicenter, Placebo-Controlled Trial [J]. Digital Chinese Medicine. 2018. 1(01):56-66.

[11] Pan Y#, Zhou F#, Song Z, Huang H, Chen Y, Shen Y, Jia Y*, Chen J*. Oleanolic acid protects against pathogenesis of atherosclerosis, possibly via FXR-mediated angiotensin (Ang)-(1-7) upregulation [J]. Biomed Pharmacother. 2018. 97:1694-1700.

[12] Li X#, Lu Z#, Zhou F, Jin W, Yang Y, Chen S, Xie Z, Zhao Y*. Indoxyl sulfate promotes the atherosclerosis through up-regulating the miR-34a expression in endothelial cells and vascular smooth muscle cells in vitro [J]. Vascul Pharmacol. 2020. 131:106763.

[13] Dong Y, Gong L, Lu X, Ye M, Lin Y, Xie S, Zhang J, Zhou F, Tang L, Zou W*, Liu M*. Changes of Transporters and Drug-metabolizing Enzymes in Nephrotic Syndrome [J]. Curr Drug Metab. 2020. 21(5):368-378.

[14] Cheng S, Zhou F, Xu Y, Liu X, Zhang Y, Gu M, Su Z, Zhao D, Zhang L, Jia Y*. Geniposide regulates the miR-101/MKP-1/p38 pathway and alleviates atherosclerosis inflammatory injury in ApoE-/- mice [J]. Immunobiology. 2019. 224(2):296-306.

[15] Yan H, Yang W, Zhou F, Li X, Pan Q, Shen Z, Han G, Newell-Fugate A, Tian Y, Majeti R, Liu W, Xu Y, Wu C, Allred K, Allred C, Sun Y, Guo S*. Estrogen Improves Insulin Sensitivity and Suppresses Gluconeogenesis via the Transcription Factor Foxo1 [J]. Diabetes. 2019. 68(2):291-304.

科研奖励:

       (1)周凤华(2/20);中药定心方系列防治心血管疾病的研究,中国中西医结合学会,科学技术奖,二等奖,获奖编号:2019001A,2019(贾钰华;周凤华;孙学刚;郭永周;赵晓山;孙晓敏;张丽华;陈育尧;余林中;丁邦晗;程赛博;杨萍;崔小冰;刁建新;徐煜凌;刘晓瑜;张蕾;潘芸芸;李杰;黄宜生)

      (2)周凤华(2/10);定心方系列方防治心律失常、动脉硬化等心血管疾病的作用与机制,广东省人民政府,广东省科技进步奖,二等奖,获奖编号:JI6-2-05,2019(贾钰华;周凤华;孙学刚;赵晓山;孙晓敏;张丽华;陈育尧;杨萍;程赛博;刁建新)