目录
更新日期:2024年3月19日
姓 名 钟华 性 别
民 族 汉族 导师层次 博士导师
技术职称 主任医师 导师类型 学术&专业型
最后学历 硕士研究生毕业 最后学位 临床医学博士专业学位
行政职务 科室主任 Email zhong8099@163.com
工作单位 南方医科大学第五附属医院 邮政编码 510900
跨学科招生
跨学科招生专业1 全科医学 招生层次类型1 专业学位硕导
跨学科招生专业2 招生层次类型2
个人简介

 南方医科大学第五附属医院创伤骨科科主任,广东省临床重点学科骨科学科带头人,主任医师,医学博士,“广东省杰出青年医学人才”,“岭南名医”,"羊城好医生“。现学术任职《中华创伤骨科》杂志特约编委;《中华养生保健》杂志编委;广东省老年保健协会创伤骨科专委会主任委员;SICOT中国部数字骨科学会委员;中国康复医学足踝康复专业委员会委员;广东省临床医学学会足踝外科专业委员会副主任委员;广东省卫生信息网络协会骨科信息化应用分会副会长;广东省中西结合学会足踝外科专业委员会常委;广东省医学会创伤学分会常务委员;广东省精准医学应用学会骨肿瘤分会常委;广东省基层医药学会创伤救治专委员常委及骨盆、髋周学组副组长等。擅长于严重骨盆、髋臼骨折,复杂关节周围骨折,足踝外科,老年骨折及复杂创面修复手术;骨肿瘤,骨骼畸形,骨不连,慢性骨髓炎的保肢手术治疗;保留关节的断肢再植术及运动创伤关节镜手术。主要的研究方向是骨植入体感染及骨缺损生物材料与基于多模态数据的骨关节创伤生物力学机制。目前主持国家自然科学基金面上项目一项,广东省自然科学基金面上项目一项,广东省医学科研基金及广州市科技功关项目多项,以第一作者或通讯作者在《Bioactive Materials》,《ACS Applied Materials & Interfaces》等国际期刊发表SCI论文10余篇。

研究领域

主要的科研方向是基于临床骨感染疾病及骨植入体感染及骨缺损难题导向,主要通过骨植入体表面改性研究,纯锌骨植入体抗菌及其分子机制研究,骨植入体纳米涂层抗菌及分子机制,载氢异质结修饰钛植入体修复感染性骨缺损研究,光响应性敏化剂的制备在早期骨感染中的应用等前沿方向探索抗菌及促感染性骨缺损修复新型生物材料。另外,基于临床骨关节创伤预防及康复需求导向,主要利用离体尸体标本生物力学测试,有限元生物力学模型或在体六自由度步态测量等多模态数据探索骨关节运动特征及创伤机制方面做了许多有意义的工作。

个人成果

一、主持国家自然科学基金项目一项,广东省自然科学基金一项,广东省医学科研基金项目多项,广州市科技攻关项目多项,获市级科技进步二等奖二项,三等奖一项;获一种肱骨远端个性化数字化接骨板国家发明专利一项;

二、代表性论文:

1.Jin Ke # , Shi Cheng # , Meng-Yu Yao , Xiao Chu , Ming Wang , Xiao-Long Zeng , Tao Yang , Chi Zhang , Hua Zhong , Yu Zhang *.Novel Strategy of Curettage and Adjuvant Microwave Therapy for the Treatment of Giant Cell Tumor of Bone in Extremities: A Preliminary Study. Orthop Surg. 2021 Feb;13(1):185-195.(2区,IF=2.071)

2.Hua Zhong#,Limin Ma#,Ming Wang#,Yan Huang,Ye Zhou,Lingling Chen,Guangmou Chen,Jianwei Li*,Jin Chen*,Yu Zhang*. Comparison of biomechanical characteristics in treatment of distal humerus fracture using different fixation plates: A finite element study[J]. Microsc Res Tech. 2019. Mar;82(3):199-205.(四区,IF:1.327)

3.Hua Zhong#, Sushuang Ma#; Yibiao Cen#; Limin Ma; Deqiang Li;Liang Bo;Chen Jin; Zhang Yu*. A Case Report of Early Unilateral External Fixation by 3D Printing and Computer-Assisted and Secondary Bone Graft Internal Fixation in Pseudarthrosis of the Tibia Surgery[J]. The Journal of International Medical Research.2020.9. 48(9):1-8.(四区,IF:1.287)

4.Shi Cheng#, Lvqin Lan#, Mei Li, Xiao Chu, Hua Zhong*, Mengyu Yao, Feng Peng*, Yu Zhang*. Pure Mg-Al layered double hydroxide film on magnesium alloy for orthopedic application [J]. ACS Omega. 2021. Sep; 6(38): 24575-24584. (二区,IF=3.512)

5.Hongwei Shao#, Shi Cheng#, Mengyu Yao#, Xiongfa Jia, Hua Zhong*, Donghui Wang, Xiujuan Fan, Qian Li, Jielong Zhou, Yu Zhang*, Feng Peng*. A pH-response chemotherapy synergistic photothermal therapy for tumor suppression and bone regeneration by mussel-inspired Mg implant [J]. Regenerative Biomaterials. 2021,Dec. 8(6): 1-11 . (二区,IF=6.353)

6.Hongfen Chen#, Chao Ding#, Yongqiang Liu#, Zhen Kong, Siling Chang, Feng Huang, Heng Li, Qingxiang Guo, Yuehua Yang*, Hua Zhong* and Shaozheng Yang. A clinical and biomechanical comparison of INFIX plus single versus double sacroiliac screw fxation for unstable pelvic ring injury[J]. Journal of Orthopaedic Surgery and Research. 2022, 17(1). (四区,IF=2.57)

7.Feng Peng#, Juning Xie#, Haiming Liu, Yufeng Zheng*, Xin Qian, Ruixiang Zhou, Hua Zhong*, Yu Zhang*, Mei Li*. Shifting focus from bacteria to host neutrophil extracellular traps of biodegradable pure Zn to combat implant centered infection, Bioactive Materials, 2023, 21, 436-449(一区,IF=16.874)

8.Zhang K, Zhou J, Wu T, Tian Q, Liu T, Wang W, Zhong H, Chen Z, Xiao X, Wu G. Combined analysis of expression, prognosis and immune infiltration of GINS family genes in human sarcoma. Aging (Albany NY). 2022 Jul 27;14(14):5895-5907. doi: 10.18632/aging.204191. Epub 2022 Jul 27. PMID: 35896011; PMCID: PMC9365567.

9.Huang, W., Zeng, X. , Li, M., Chen, H., Lai, H., Yan, Y., Zhong, H. & Zhang, Y. "A combined anterior cruciate ligament/Meniscal injury alters the patellofemoral joint kinematics of anterior cruciate ligament-deficient knees during a single-leg lunge exercise: A cross-sectional study. " Frontiers in Bioengineering and Biotechnology, 10.3389/fbioe.2022.1016859(1区,IF=6.064)

10.Wang Q, Li C, Song Y, Shi Q, Li H, Zhong H, Wang J, Hu F. Acene enlargement for absorption red-shifting and photosensitization enhancement of photosensitizers with aggregation-induced emission. Chem Sci. 2022 Dec 10;14(3):684-690. doi: 10.1039/d2sc05454j. PMID: 36741529; PMCID: PMC9847635 (2区,IF 8.4,)

11.Yang S, Liu Y, Ma S, Ding C, Kong Z, Li H, Huang F, Chen H, Zhong H. Stress and strain changes of the anterior cruciate ligament at different knee flexion angles: A three-dimensional finite element study. J Orthop Sci. 2023 Jul 3:S0949-2658(23)00178-1. doi: 10.1016/j.jos.2023.05.015. Epub ahead of print. PMID: 37407345 (4区,IF 1.7)

12.Wu B, Gan Z, Tao S, Wang Q, Song Y, Zhong H, Hu F. Dextran-Cholesterol Carrier Encapsulated Efficient Photosensitizer for the Photodynamic Killing of Cancer Cells. Molecules. 2023 May 28;28(11):4404. doi: 10.3390/molecules28114404. PMID: 37298877; PMCID: PMC10254848.(3 区,IF 4.6)

13.Hongfen Chen#, Chao Ding#, Yongqiang Liu#, Zhen Kong, Siling Chang, Feng Huang, Heng Li, Qingxiang Guo, Yuehua Yang*, Hua Zhong* and Shaozheng Yang. A clinical and biomechanical comparison of INFIX plus single versus double sacroiliac screw fxation for unstable pelvic ring injury[J]. Journal of Orthopaedic Surgery and Research. 2022, 17(1). (四区,IF=2.57)

14.Feng Peng, Mei Li, Dongdong Zhang, Dengwen Zheng, Donghui Wang, Hua Zhong. Chlorite-incorporated clay nanosheets as acid and H2O2-activated gas-bombs for combating peri-implant infection, Applied Clay Science, 245 (2023) 107140(IF=5.6,中科院2区)

15.Yin L, Tang Q, Ke Q, Zhang X, Su J, Zhong H, Fang L. Sequential Anti-Infection and Proangiogenesis of DMOG@ZIF-8/Gelatin-PCL Electrospinning Dressing for Chronic Wound Healing. ACS Appl Mater Interfaces. 2023 Oct 25;15(42):48903-48912. doi: 10.1021/acsami.3c09584. Epub 2023 Oct 16. PMID: 37877332.(IF=10.38,中科院2区)

16.Zhang K, Zhou J, Wu T, Tian Q, Liu T, Wang W, Zhong H, Chen Z, Xiao X, Wu G. Combined analysis of expression, prognosis and immune infiltration of GINS family genes in human sarcoma. Aging (Albany NY). 2022 Jul 27;14(14):5895-5907. doi: 10.18632/aging.204191. Epub 2022 Jul 27. PMID: 35896011; PMCID: PMC9365567.

17.Wu B, Gan Z, Tao S, Wang Q, Song Y, Zhong H, Hu F. Dextran-Cholesterol Carrier Encapsulated Efficient Photosensitizer for the Photodynamic Killing of Cancer Cells. Molecules. 2023 May 28;28(11):4404. doi: 10.3390/molecules28114404. PMID: 37298877; PMCID: PMC10254848.(IF=4.9,中科院3区)

18.Luo G, Xu Z, Zhong H, Shao H, Liao H, Liu N, Jiang X, Zhang Y, Ji X. Biodegradable photothermal thermosensitive hydrogels treat osteosarcoma by reprogramming macrophages. Biomater Sci. 2023 Apr 11;11(8):2818-2827. doi: 10.1039/d2bm01900k. PMID: 36826467.(IF=6.6,中科院2区)

19.Jiang G, Tian Q, Shi P, Li Z, Li Y, Chen J, Wang W, Chen R, Zhong H, Wu G. Association of NCAP family genes with prognosis and immune infiltration of human sarcoma. Aging (Albany NY). 2023 May 9;15(10):4108-4121. doi: 10.18632/aging.204683. Epub 2023 May 9. PMID: 37192046; PMCID: PMC10258000.(IF=5.2,中科院3区)