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更新日期：2024年10月28日
姓 名 邵龙泉 性 别 男
民 族 汉族 导师层次 博士导师
技术职称 主任医师 导师类型 学术&专业型
最后学历 博士研究生毕业 最后学位 口腔医学博士专业学位
行政职务 副院长 Email shaolongquan@smu.edu.cn
工作单位 南方医科大学口腔医院 邮政编码 510280
个人简介

邵龙泉，二级教授，主任医师，博士生导师，博士后合作导师。国家百千万人才工程国家级人选，国家有突出贡献中青年专家，国务院政府特殊津贴，广东省高等学校“千百十工程”省级培养人才，广东最美科技工作者，美国罗马琳达大学牙学院访问学者，广州市“青年科技人员托举工程”导师，爱思唯尔中国高被引学者。

中华口腔医学会口腔医学科研管理分会副主委，全国高等学校口腔医学专业第六届教材评审委员会委员，人卫版全国统编教材《口腔修复学》和《口腔医学》编委。《口腔疾病防治》杂志主编，《口腔颌面修复学杂志》杂志副主编，国际期刊《BMC Pharmacol Toxico》Associate Editor。

已发表学术文章330余篇，其中，以第一作者或通讯作者身份在Adv Funct Mater、Bioact Mater、ACS Nano、Adv Drug Deliver Rev、Adv Sci、Chem Eng J、Int J Oral Sci、J Hazard Mater、Small、J Control Release、J Nanobiotechnol、Adv Healthc Mater等杂志上发表文章130篇（其中，中科院小类一区文章40篇，ESI热点文章1篇，高被引文章3篇，单篇最高被引频次3032次，H指数：41）。主持国家十三五重点专项课题1项，国家自然科学基金7项。第一完成人获得广东省科技进步二等奖1项、中国整形美容协会科学技术奖二等奖2项、广东医学科技奖二等奖1项，中华口腔医学会科技奖三等奖1项。第一起草人制定国家职业技能标准1项。

 

研究领域

1.口腔组织工程与再生

2.生物安全性评价

3.抗菌机制研究

个人成果

1.     Liu WJ#, Wang QY, Luo HY, Luo BC, Zhao FJ, Kang, YY, Zhang YL, Shao LQ*. Nano-graphene oxide promotes angiogenesis by inhibiting isocitrate dehydrogenase 1 effect on osteoclast differentiation and platelet-derived growth factor BB secretion. ACS Nano, 2024, 18: 22390-22403. (IF 2023=15.8, 中科院小类分区=1区)

2.     Hu C#, He GX#, Yang YJ, Wang N, Zhang YL, Su Y, Zhao FJ, Wu JR, Wang LL, Lin YQ, Shao LQ*. Nanomaterials Regulate Bacterial Quorum Sensing: Applications, Mechanisms, and Optimization Strategies. Adv Sci, 2024, 2306070. (IF 2023=14.3, 中科院小类分区=1区)

3.     Lai X#, Wang ML, Zhang Z, Chen SY, Tan XE, Liu WJ, Liang HM, Li L, Shao LQ*. ZNPs reduce epidermal mechanical strain resistance by promoting desmosomal cadherin endocytosis via mTORC1-TFEB-BLOC1S3 axis. J Nanobiotechnol, 2024, 22: 312-329. (IF 2023=10.6, 中科院小类分区=1区)

4.     Jin NQ#, Wang ZL#, Yin CC, Bu WH, Jin N, Ou LL, Xie WQ, He JK, Lai X, Shao LQ*. Novel Carbon Quantum Dots Precisely Trigger Ferroptosis in Cancer Cells through antioxidants inhibition synergistic nano-catalytic activity. ACS Appl Mater Interfaces, 2024, 16(29): 37456-37467. (IF 2022=8.3, 中科院小类分区=2区)

5.     Xie WQ#, Lu JJ, Chen YC, Wang X, Lu HZ, Li QX, Jin NQ, He JK, Ou LL, Ni J, Guo HL, Shen YQ, Shao LQ*. Investigating the role of B cells expressing TCL1A in tertiary lymphoid structure formation and prognosis of oral squamous cell carcinoma. J Transl Med, 2024, 22: 477. (IF 2023=6.1, 中科院小类分区=2区)

6.     Zhu ZJ#, Zhang YQ, Wang RM, Dong YJ, Wu JR*, Shao LQ*. Zinc oxide nanoparticles disrupt the blood-milk barrier via Z-DNA binding protein 1-triggered PANoptosis. Ecotoxicol Environ Saf, 2024, 283: 116777. (IF 2023=6.2, 中科院小类分区=1区)

7.     Qiao SJ#, Kang YY#, Tan XE, Zhou XR, Zhang C, Lai SL, Liu J*, Shao LQ*. Nanomaterials-induced programmed cell death: Focus on mitochondria. Toxicology, 2024, 504: 153803. (IF 2023=4.8, 中科院小类分区=2区)

8.     Liao YH#, Mai YL, Liu XC, Wu ZJ, Wang SZ, Xie BZ, Gong Y, Xie YF, Fang Z, Wu JY, Shao LQ*, Wang WS*, Liu YS*. Nanostructured Cruciform Phototheranostic Agents for Efficient Multimodal Imaging-Guided Type I Photodynamic/Photothermal Synergistic Therapy. Dyes Pigments, 2024, 229, 112283. (IF 2023=4.1, 中科院小类分区=1区)

9.     Zhao FJ#, Yang Z#, Xiong HC, Yan Y, Chen XF*, Shao LQ*. A bioactive glass functional hydrogel enhances bone augmentation via synergistic angiogenesis, self-swelling and osteogenesis. Bioact Mater, 2023, 22: 201-210. (IF 2022=18.9, 中科院小类分区=1区)

10.     Ou LL#, Tan XE, Qiao SJ, Luo RH, Su Y, Wu JR, Liu WJ, Lai X, Zhang YL, Liu J, Kang YY, Zhao FJ, Shao LQ*. G raphene-based material-mediated immunomodulation in tissue engineering and regeneration: mechanism and significance. ACS Nano, 2023, 17(19): 18669-18687. (IF 2022=17.1, 中科院小类分区=1区)

11.     Su Y#, Ye LL, Hu C, Zhang YL, Liu J, Shao LQ*. Periodontitis as a promoting factor of T2D: current evidence and mechanisms. Int J Oral Sci, 2023, 15(1): 25. (IF 2022=14.9, 中科院小类分区=1区)

12.     Zhang YL#, Zhang YL#, Lei Y, Wu JR, Kang YY, Zheng S, Shao LQ*. MDM2 upregulation induces mitophagy deficiency by Mic60 ubiquitination in fetal microglial inflammation and consequently neuronal DNA damage caused by pregnancy exposure to ZnO-NPs. J Hazard Mater, 2023, 457: 131750. (IF 2022=13.6, 中科院小类分区=1区)

13.     Chen SY#, Su Y, Zhang MJ, Zhang YL, Xiu PM, Wei L, Zhang QX, Zhang XL, Liang HB, Lee APW, Shao LQ*, Xiu JC*. Insights into the toxicological effects of nanomaterials on atherosclerosis: mechanisms involved and Influence Factors. J Nanobiotechnol, 2023, 21(1): 140. (IF 2022=10.2, 中科院小类分区=1区)

14.     Zhao FJ#, Qiu YH#, Liu WJ, Zhang YL, Liu J, Bian LM*, Shao LQ*. Biomimetic hydrogels as the inductive endochondral ossification template for promoting bone regeneration. Adv Healthc Mater, 2023, e2303532. (IF 2022=10.0, 中科院小类分区=1区)

15.     Zhang YL#, Mo JY#, Zheng CQ, Zeng YT, Zhou ZY, Zhang YL, Li MH, Sheng LY, Zheng YF, Shao LQ*, Yang DH*, Yan WJ*. MY-1 loaded nano-hydroxyapatite accelerated bone regeneration by increasing type Ⅲ collagen deposition in early-stage ECM via a Hsp47 dependent mechanism. Adv Healthc Mater, 2023, 12(20): e2300332. (IF 2022=10.0, 中科院小类分区=1区，封面文章)

16.     Chen AJ#, Wang RL, Kang YY, Liu J, Wu JR, Zhang YL, Zhang YL, Shao LQ*. Tongue-brain-transported ZnO NPs induced abnormal taste perception. Adv Healthc Mater, 2023, 12(17): e2203316. (IF 2022=10.0, 中科院小类分区=1区，封面文章)

17.     Wang N#, Wang Z#, Hu C, Yang YJ, He GX, Shao LQ*, You J*. Effect of perioperative cognitive behavioral interventions on pain, anxiety, and sleep quality in elderly patients after sinus floor elevation and immediate implantation: A randomized controlled trial. Technol Health Care, 2023, 31: S323-S332. (IF 2022=1.6, 中科院小类分区=4区)

18.   Liu WJ#, Luo HY, Wei QW, Liu J, Wu JR, Zhang YL, Chen LL, Ren WC, Shao LQ*. Electrochemically derived nanographene oxide activates endothelial tip cells and promotes angiogenesis by binding endogenous lysophosphatidic acid. Bioact Mater, 2022, 9: 92-104. (IF 2022=18.9, 中科院小类分区=1区)

19.   Wu JR#, Zhu ZJ, Liu WJ, Zhang YL, Kang YY, Liu J, Hu C, Wang RL, Zhang MJ, Chen LL, Shao LQ*. How nanoparticles open the paracellular route of biological barriers: mechanisms and prospects. ACS Nano, 2022, 16(10): 15627-15652. (IF 2022=17.1, 中科院小类分区=1区)

20.   Kang YY#, Yin SH#, Liu J, Jiang YP, Huang ZD, Chen LL, Shao LQ*. Nano-graphene oxide depresses neurotransmission by blocking retrograde transport of mitochondria. J Hazard Mater, 2022, 424(Pt D): 127660. (IF 2022=13.6, 中科院小类分区=1区)

21.   Chen AJ#, Kang YY, Liu J, Wu JR, Feng XL, Wang ML, Zhang YL, Wang RL, Lai X, Shao LQ*. Improvement of synaptic plasticity by NPs and the related mechanisms: Applications and prospects. J Control Release, 2022, 347: 143-163. (IF 2022=10.8, 中科院小类分区=1区)

22.   Jiang YP#, Kang YY, Liu J, Yin SH, Huang ZD, Shao LQ*. Nanomaterials alleviating redox stress in neurological diseases: mechanisms and applications. J Nanobiotechnol, 2022, 20: 265. (IF 2022=10.2, 中科院小类分区=1区)

23.   Ling MJ#, Sun R, Li G, Syeda MZ, Ma W, Mai ZY, Shao LQ*, Tang LG*, Yu ZQ*. NIR-II Squaraine Nanoparticle Targeting EGFR for Oral Cancer Theranostics. Nano Res, 2022, 15(7): 6288-6296. (IF 2022=9.9, 中科院小类分区=1区)

24.   Hu C#, Lin YQ, Yang YJ, Wang LL, Liang HM, Wu JR, He GX, Shao LQ*. High-performance dental composites based on hierarchical reinforcements. J Dent Res, 2022, 101(8): 912-920. (IF 2022=7.6, 中科院小类分区=1区)

25.   Luo HY#, Liu WJ, Zhou YC, Zhang YL, Wu JR, Wang RL, Shao LQ*. Stage-specific requirement for METTL3-dependent m6A modification during dental pulp stem cell differentiation. J Transl Med, 2022, 20: 605. (IF 2022=7.4, 中科院小类分区=2区)

26.   Zhang CG#, Wang WL*, Hao XD, Peng Y, Zheng YL, Liu J, Kang YY, Zhao FJ, Luo ZT, Guo JJ, Xu BS, Shao LQ*, Li GQ*. A Novel Approach to Enhance Bone Regeneration by Controlling the Polarity of GaN/AlGaN Heterostructures. Adv Funct Mater, 2021, 31(5): 2007487. (IF 2021=19.924, 中科院小类分区=1区)

27.   Hu C#, Yang YJ#, Lin YQ, Wang LL, Ma RY, Zhang YL, Feng XL, Wu JR, Chen LL, Shao LQ*. GO-Based Antibacterial Composites: Application and Design strategies. Adv Drug Deliver Rev, 2021, 178: 113967. (IF 2021=17.873, 中科院小类分区=1区)

28.   Kang YY#, Liu J#, Jiang YP, Yin SH, Huang ZD, Zhang YL, Wu JR, Chen LL, Shao LQ*. Understanding the interactions between inorganic-based nanomaterials and biological membranes. Adv Drug Deliver Rev, 2021, 175: 113820. (IF 2021=17.873, 中科院小类分区=1区)

29.   Feng XL#, Zhang YQ#, Luo RH, Lai X, Chen AJ, Zhang YL, Chen LL, Shao LQ*. Graphene oxide disrupted mitochondrial homeostasis through inducing intracellular redox deviation and autophagy-lysosomal network dysfunction in SH-SY5Y cells. J Hazard Mater, 2021, 416: 126158. (IF 2021=14.224, 中科院小类分区=1区)

30.   Lai X#, Wang ML, Zhu YX, Feng XL, Liang HM, Wu JR, Nie L, Li L*, Shao LQ*. ZnO NPs delay the recovery of psoriasis-like skin lesions through promoting nuclear translocation of p-NFκB p65 and cysteine deficiency in keratinocytes. J Hazard Mater, 2021, 410: 124566. (IF 2021=14.224, 中科院小类分区=1区)

31.   Wang ML#, Huang XW, Zheng HX, Tang YM, Zeng K, Shao LQ*, Li L*. Nanomaterials applied in wound healing: mechanisms, limitations and perspectives. J Control Release, 2021, 337: 236-247. (IF 2021=11.467, 中科院小类分区=1区)

32.   Zhang YL#, Zhang YL#, Wu JR, Liu J, Kang YY, Hu C, Feng XL, Liu WJ, Luo HY, Chen AJ, Chen LL, Shao LQ*. Effects of carbon-based nanomaterials on vascular endothelia under physiological and pathological conditions: interactions, mechanisms and potential therapeutic applications. J Control Release, 2021, 330: 945-962. (IF 2021=11.467, 中科院小类分区=1区)

33.   Liao YH#, Wang RL#, Wang SZ, Xie YF, Chen HH, Huang RJ, Shao LQ*, Zhu QH*, Liu YS*. Highly Efficient Multifunctional Organic Photosensitizer with Aggregation-Induced Emission for In Vivo Bioimaging and Photodynamic Therapy. ACS Appl Mater Inter, 2021, 13(46): 54783-54793. (IF 2021=10.383, 中科院小类分区=2区)

34.   Sun T#*, Kang YY, Liu J, Zhang YL, Ou LL, Liu XN, Lai RF, Shao LQ*. Nanomaterials and hepatic diseases: toxicokinetics, disease types, intrinsic mechanisms, and liver susceptibility. J Nanobiotechnol, 2021, 19(1): 108. (IF 2021=9.429, 中科院小类分区=2区)

35.   Luo HY#, Liu WJ, Zhang YL, Yang YQ, Jiang X, Wu SQ*, Shao LQ*. METTL3-mediated m6A modification regulates cell cycle progression of dental pulp stem cells. Stem Cell Res Ther, 2021, 12(1): 159. (IF 2021=8.079, 中科院小类分区=2区)

36.   Kang YY#, Liu J#, Yin SH, Jiang YP, Feng XL, Wu JR, Zhang YL, Chen AJ, Zhang YQ, Shao LQ*. Oxidation of Reduced Graphene Oxide via Cellular Redox Signaling Modulates Actin-Mediated Neurotransmission. ACS Nano, 2020, 14(3): 3059-3074. (IF 2020=15.881, 中科院小类分区=1区)

37.   Zhao FJ#, Zhang CG#, Liu J, Liu L, Cao XD, Chen XF*, Lei B*, Shao LQ*. Periosteum structure/function mimicking bioactive scaffolds with piezoelectric/chem/nano signals for critical sized bone regeneration. Chem Eng J, 2020, 402: 126203. (IF 2020=13.273, 中科院小类分区=1区)

38.   Wu JR#, Lai X, Cui GM, Chen QY, Liu J, Kang YY, Zhang YL, Feng XL, Hu C, Shao LQ*. Dual effects of JNK activation in blood-milk barrier damage induced by zinc oxide nanoparticles. J Hazard Mater, 2020, 399: 122809. (IF 2020=10.588, 中科院小类分区=1区)

39.   Wang RL#, Chen LJ, Shao LQ*. The mTOR/ULK1 signaling pathway mediates the autophagy-promoting and osteogenic effects of dicalcium silicate nanoparticles. J Nanobiotechnol, 2020, 18(1): 119. (IF 2020=10.435, 中科院小类分区=2区)

40.   Liu WJ#, Zhang GL, Wu JR, Zhang YL, Liu J, Luo HY, Shao LQ*. Insights into the angiogenic effects of nanomaterials: potential applications and related mechanisms. J Nanobiotechnol, 2020, 18(1): 9. (IF 2020=10.435, 中科院小类分区=2区)

41.   Zhang C#, Feng XL, He LW, Zhang YQ, Shao LQ*. The interrupted effect of autophagic flux and lysosomal function induced by graphene oxide in p62-dependent apoptosis of F98 cells. J Nanobiotechnol, 2020, 18(1): 52. (IF 2020=10.435, 中科院小类分区=2区)

42.   Feng XL#, Zhang YQ#, Zhang C, Lai X, Zhang YL, Wu JR, Hu C, Shao LQ*. Nanomaterial-mediated autophagy: coexisting risks and benefits in biomedicine. Part Fibre Toxicol, 2020, 17: 53. (IF 2020=9.400, 中科院小类分区=1区)

43.   Liu J#, Kang YY, Yin SH, Chen AJ, Wu JR, Liang HM, Shao LQ*. Key Role of Microtubule and Its Acetylation in a Zinc Oxide Nanoparticle–Mediated Lysosome-Autophagy System. Small, 2019, 15(25): e1901073. (IF 2019=11.459, 中科院小类分区=1区)