目录
更新日期:2025年10月9日
姓 名 邓凯贤 性 别
民 族 汉族 导师层次 博士导师
技术职称 主任医师 导师类型 学术&专业型
最后学历 硕士研究生毕业 最后学位 医学博士学位
行政职务 副院长 Email kaixiandeng8458@163.com
工作单位 南方医科大学第八附属医院(佛山市顺德区第一人民医院) 邮政编码 528300
个人简介

邓凯贤,南方医科大学顺德医院副院长、妇科学科带头人,主任医师,医学博士,博士研究生导师,博士后合作导师。南方医科大学顺德医院妇科主任,佛山市重点专科学科带头人,国家住院医师规范化培训妇产科基地教学主任,佛山市卵巢功能障碍性疾病工程技术中心主任。

现任中国医师协会妇产科分会委员、中国康复医学会妇产科分会常委、广东省康复医学会妇科分会主任委员、佛山市医师协会妇科医师分会主任委员、广东省医疗行业协会妇产科管理分会副主任委员、广东省健康管理学会妇科肿瘤专委会副主任委员、广东省医师协会妇科分会常委、广东省女创新工作室负责人、佛山市卵巢功能障碍性疾病精准工程中心主任等。曾获“佛山市青年岗位能手”、“佛山市杰出青年医学人才”等光荣称号。致力于影响女性生殖能力疾病及恶性肿瘤防治研究。

聚焦女性生育力保护临床与转化研究,围绕早发性卵巢功能不全机制与精准治疗、剖宫产术后子宫瘢痕憩室分子机制与诊疗策略、妇科肿瘤微环境与靶向治疗等方向取得突破性进展,率先构建AI辅助妇科诊疗系统。与多个国际国内研究团队保持密切合作。近五年主持持国家自然科学基金及广东省重点项目等国家级和省市级课题共17项(累计经费450万元,单笔最高125万元);以第一/通讯作者发表SCI及核心期刊论文29篇(11篇Q1区,总IF=140,被引500+次);获授权专利5项(1项PCT);主编学术专著2部;牵头3项多中心GCP项目。

研究领域

1.子宫瘢痕憩室与早发性卵巢功能不全的病理生理机制与治疗新策略的基础研究。

2.干细胞及新型生物材料在生育力保护中的作用机制及临床转化研究。

3.妇科恶性肿瘤发病机制及分子靶向治疗。

4.人工智能在妇科疾病诊断及临床治疗决策中的应用。

个人成果

主持各级课题共15项

主持国自然面上项目1项,省市级课题14项.

代表性论著

1. Huang S, Liu H, Liao K, Hu Q, Guo R*, Deng K*. Functionalized GO Nanovehicles with Nitric Oxide Release and Photothermal Activity-Based Hydrogels for Bacteria-Infected Wound Healing[J]. ACS Appl Mater Interfaces. 2020, 12(26): 28952-28964.

2. Hu Q, Xie N, Liao K, Huang J, Yang Q, Zhou Y, Liu Y, Deng K*. An injectable thermosensitive Pluronic F127/hyaluronic acid hydrogel loaded with human umbilical cord mesenchymal stem cells and asiaticoside microspheres for uterine scar repair[J]. Int J Biol Macromol. 2022, 219: 96-108.

3. Sang S, Jiang Z, Xie N, Rao H, Liao K, Hu Q, Zhang Z*, Guo R, Fan T, Deng K*. Black phosphorus nanosheets and paclitaxel encapsulated hydrogel for synergistic photothermal-chemotherapy[J]. Nanophotonics. 2021, 10(10): 2625-2637. 

4. Chen L, Li L, Mo Q, Zhang X, Chen C, Wu Y, Zeng X, Deng K*, Liu N, Zhu P, Liu M, Xiao Y. An injectable gelatin/sericin hydrogel loaded with human umbilical cord mesenchymal stem cells for the treatment of uterine injury. Bioeng Transl Med. 2022 May 18;8(1):e10328.

5. Yang Q, Huang J, Liu Y, Mai Q, Zhou Y, Zhou L, Zeng L, Deng K*. Human Umbilical Cord Mesenchymal Stem Cells Promote Anti-Inflammation and Angiogenesis by Targeting Macrophages in a Rat Uterine Scar Model. Stem Cell Rev Rep. 2024 Aug;20(6):1555-1568.

6. Huang J, Wang G, Liao K, Xie N, Deng K*. UCP1 modulates immune infiltration level and survival outcome in ovarian cancer patients[J]. J Ovarian Res. 2022, 15(1): 16.

7. Huang J, Zhou L, Deng K*. Prognostic marker C3AR1 is associated with ovarian cancer cell proliferation and immunosuppression in the tumor microenvironment. J Ovarian Res. 2023 Apr 1;16(1):64.

8. Zhou Y, Huang J, Zeng L, Yang Q, Bai F, Mai Q, Deng K*. Human mesenchymal stem cells derived exosomes improve ovarian function in chemotherapy-induced premature ovarian insufficiency mice by inhibiting ferroptosis through Nrf2/GPX4 pathway. J Ovarian Res. 2024 Apr 15;17(1):80.

9. Chen L, Mo Q, Wu Y, Chen W, Deng K*, Xiao Y*. Ameliorative effect of Salidroside on the cyclophosphamide-induced premature ovarian failure in a rat model. Free Radic Res. 2024 Feb;58(2):107-116.

10. Deng K, Liu W, Chen Y, Lin S, Huang X, Wu C, Wang H, Wang J, Chen L, Liu X, Zheng Y. Obstetric and Gynecologic Outcomes after the Transvaginal Repair of Cesarean Scar Defect in a Series of 183 Women[J]. J Minim Invasive Gynecol. 2021, 28(5): 1051-1059.

11. Huang J, Liu X, Hou Y, Liu Y, Liao K, Xie N, Deng K*. Macrophage polarisation in caesarean scar diverticulum[J]. J Clin Pathol. 2022, 0(207926): 1-5.

12. Liang J, Chen X, Huang J, Nie W, Yang Q, Huang Q, Deng K*. Implications of serum uric acid for female infertility: results from the national health and nutrition examination survey, 2013-2020. BMC Womens Health. 2023 Mar 11;23(1):103.

13. Chen X, Liang J, Yang Q, Huang J, Li L, Deng K*. Age affects the association between socioeconomic status and infertility: a cross-sectional study. BMC Womens Health. 2023 Dec 19;23(1):675.

14. Yang Q, Wuliu J, Zeng L, Huang J, Tang G, Zhang J, Liao K, Deng K*. Association between a body shape index and female infertility: a cross-sectional study. BMC Womens Health. 2024 Sep 4;24(1):486.

15. Chen X, Huang J, Liang J, Li L, Deng K*. Association of Serum Triglyceride and Stress Urinary Incontinence in Women From the National Health and Nutrition Examination Survey: A Cross-Sectional Study[J]. Urology. 2022: S0090-4295(22)00989-X. 

16. Lu M, Zhang Y, Yang Q, Huang J, Deng K*. Linking Lipid Profile to Stress Urinary Incontinence in US Women: A National Cross-Sectional Study. Int J Womens Health. 2025 Jun 3;17:1631-1640.

17. Zhang C, Huang J, Yang Q, Zeng L, Deng K*. Regulatory mechanisms of macrophage–myofibroblast transdifferentiation: A potential therapeutic strategy for fibrosis.

18. Huang J, Zeng L, Yang Q, Deng K*. Integrated multi-omics analysis identifies TLR4-mediated mechanisms in ATBC-induced ovarian dysfunction and female infertility: A network toxicology, transcriptomic, and Mendelian randomization study. J Ovarian Res. 2025 Jun 3;18(1):120.

19. Huang J, Liu Y, Zeng L, Zhang J, Yang Q, Deng K*. Establishment and Evaluation of a Stable and Reliable Rat Model of Cesarean Scar Diverticulum. FASEB J. 2025 May 31;39(10):e70617. 

20. 杨晓霖,杨志芬,邓凯贤*.围生期叙事照护与生育关怀叙事生态研究[J].医学与哲学,2023,44(03):42-45.