现任南方医科大学珠江医院影像中心学术带头人，国家自然科学基金评审专家

担任中国医师协会放射学分会全国委员见急诊工作组副组长；中华医学会放射学分会分子影像学组委员；国家卫生计生委脑卒中防治工程专家委员会神经影像专业委员会委员；中国卒中学会脑血流与代谢分会常委，广东省医师协会放射学分会副主任委员，广东省医师协会医学影像技师分会副主任委员，广东省医院管理委员会医院医学影像管理分会副主任委员，广东省卒中学会医学影像分会副主任委员；广东省脑发育与脑病防治学会副理事长；广东省精准医学应用学会脑活检技术分会副主任委员。

  1984年本科毕业于上海第二军医大学，1990年硕士研究生毕业于广州中山医科大学，2005年博士研究生毕业于广州第一军医大学，2008-2009赴美国约翰.霍普金斯大学医学院做访问学者，1998年任第一军医大学附属珠江医院放射科副主任，2019年任南方医科大学珠江医院放射科主任、影像教研室主任（兼）。

  主要研究方向是中枢神经系统影像学诊断及CT导引下的介入放射学，通过脑功能磁共振成像技术，首次在活体证实人脑纹状体边缘区参与了数字学习、记忆功能，并对人脑学习、记忆的环路及人脑认知功能的MRI成像进行了研究；研究成果获中华科技一等奖及广东省科学技术一等奖（主要参与者）；近年来，主要研究酰胺质子转移MR成像技术应用于脑胶质瘤的成像，为脑胶质瘤的分级诊断、鉴别诊断、对靶向药治疗的敏感性及预后判定提供了重要依据。

  承担国家自然科学基金四项，广东省自然科学基金三项，大学重点临床研究项目一项，发表SCI论文30多篇，包括Nature、Neuroimage、ER、MRM等，参编著作5部。

中枢神经系统影像学诊断及CT导引下的介入放射学

[1]  Zhibo Wen，Shuguang Hu，Fanheng Huang，Xianlong Wang，Linglang Guo，Xianyue Quan，Silun Wang，Jinyuan Zhou*.MR Imaging of High-grade Brain Tumors Using Endogenous Protein and Peptide-Based Contrast．Neuroimage. 2010；51：616-622（IF5.7）．

[2] Jinyuan Zhou，Erik Tryggested，Zhibo Wen，Bachchu Lal，Tingting Zhou， Rachel Grossman， Silun Wang， Kun Yan，De-Xue Fu，Eric Ford， Betty Tyler， Jaishri Blakeley，John Laterra & Peter C M van Zijl．Differentiation between glioma and radiation necrosis using molecular magnetic resonance imaging of endogenous proteins and peptides. Nature Medicine 2011:17,130-134 (IF 27.136)

[3]Shanshan Jiang, Hao Yu, Xianglong Wang, Shilong Lu, Yufa Li，Lyujin Feng, Yi Zhang, Hye-Young Heo, Dong-Hoon Lee, Jinyuan Zhou, Zhibo Wen*. Molecular MRI differentiation between primary central nervous system lymphomas and high-grade gliomas using endogenous protein-based amide proton transfer MR imaging at 3 Tesla. Eur Radiol:（2016）26:64-71

[4]Hao Yu. Huiling Lou. Tianyu Zou. Xianglong Wang. Shanshan Jiang. Zhongqing Huang. Yongxing Du. Chunxiu Jiang. Ling Ma. Jianbin Zhu. Wen He. Qihong Rui. Jianyuan Zhou. Zhibo Wen*.Applying protein-based amideproton transfer MR imaging to distinguish solitary brain metastases from glioblastoma. Eur Radiol(2017)27:4516-4524(3.9)

[5].Shanshan Jiang, Tianyu Zou, Charles G. Eberhart, Maria A.V. Villalobos, Hye-Young Heo, Yi Zhang, Yu Wang, Xianglong Wang, Hao Yu, Yongxing Du, Peter C.M. van Zijl, Zhibo Wen, and Jinyuan Zhou. Predicting IDH Mutation Status in GradeⅡGliomas Using Amide Proton Transfer-Weighted (APTw) MRI. Magnetic Resonance in Medicine 16 July 2017.

[6]．Shanshan Jiang, Qihong Rui, Yu Wang,Hye-Young Heo， Tianyu Zou, Hao Yu, Yi Zhang, Xianglong Wang, Yongxing Du, Xinrui Wen, Fangyao Chen, Jihong Wang, Charles G. Eberhart, Jinyuan Zhou, Zhibo Wen*. Discriminating MGMT promoter methylation status in patients ith glioblastoma employing amide proton transfer-weighted MRI metrics. Eur Radiol November,6 2017

[7]． Zou T, Yu H, Jiang C, Wang X, Jiang S, Rui Q, Mei Y, Zhou J, Wen Z*. Differentiating the histologic grades of gliomas preoperatively using amide proton transfer-weighted (APTW) and intravoxel incoherent motion MRI. NMR Biomed. 2018 Jan;31(1). doi: 10.1002/nbm.3850. Epub 2017 Nov 3

[8 Z.-Q. Huang,Z.-H. Meng, Z.-J. Hou, S.-Q. Huang,J.-N. Chen, H. Yu, L.-J.Feng,Q.-J. Huang P.-A. Li and Z.-B. Wen*,Geometric Parameter Analysis of Ruptured and Unruptured Aneurysms in Patients with Symmetric Bilateral Intracranial Aneurysms: A Multicenter CT Angiography Study AJNR Aug 2016;37: 1413-17.

[9] Huang ZQ¹, Zhou XW², Hou ZJ³, Huang SQ⁴, Meng ZH², Wang XL⁵, Yu H⁵, Feng LJ⁵, Wang QJ⁶, Li PA⁷, Wen ZB^8.Risk factors analysis of mirror aneurysms: A multi-center retrospective study based on clinical and demographic profile of patients. Eur J Radiol. 2017 Nov;96:80-84. doi: 10.1016/j.ejrad.2017.09.015. Epub 2017 Sep 29

[10]Hao Yu, Xinrui Wen, Pingping Wu, Yueqin Chen, Tianyu Zou, Xianlong Wang, Shanshan Jiang Jianyuan Zhou, Zhibo Wen*. Can amide proton transfer-weighted imaging differentiate tumor grade and predict Ki-67 proliferation status of meningioma?European Radiology,2019;29(10)5298-5306.

[11]Jianbin Zhu，Sujan Thapa， XianlongWang，Chunxiu Jiang， YaomingQu，ZhiboWen*。Isolated Intracranial Myeloid Sarcoma at Age 6 Months with Metastases: Case Report and Review of the Literature. Clin Neuroradiol:Published online:02 April 2019 .

[12] Xiao Liu1,2, Hong-kui Yu2, Li-xian Gu2, Jia-kun Chen2 and Zhi-bo Wen*.Atropine Premedication Facilitates Ultrasound-Guided Reduction by Saline Enema in Children With Intussusception. Frontiers in Pharmacology; Vol 10,2019:1-7

[13] Jianbin Zhu, Yaoming Qu, Xianlong Wang, Chunxiu Jiang, Jianhua Mo, Jiandong Xi, Zhibo Wen*. Risk factors associated with pulmonary hemorrhage and hemoptysis following percutaneous CT-guided transthoracic lung core needle biopsy: a retrospective study of 1,090 cases. Quantitative imaging in medicine and surgery. 2020;10(5):1008-1020.

[14]. Jianbin Zhu, Xianlong Wang, Yaoming Qu, Zhibo Wen*. CT-guided core needle biopsy of the lung in patients with primary malignancy suspected of lung metastasis: 5-year experience from a single institution. Diagnostic and Interventional Radiology. 2021;27(4):534-541.

[15]Xiao Liu1,2 & Hong-kui Yu1 & Shu-ya Sheng3 & Si-min Liang2 & Hao Lu2 & Rui-yun Chen2 & Min Pan2 & Zhi-bo Wen1.Quantitative evaluation of passive muscle stiffness by shear wave elastography in healthy individuals of different ages.European Radiology https://doi.org/10.1007/s00330-020-07367-7.

[16] Jian-Long He a,b , Lin Luo b , Zhen-Dong Luo b , Jian-Xun Lyu b , Ming-Yen Ng b,c , Xin-Ping Shen b,**, Zhibo Wen.Diagnostic performance between CT and initial real-time RT-PCR for clinically suspected 2019 coronavirus disease (COVID-19) patients outside Wuhan, China Respiratory Medicine 168 (2020) 105980

[17]Yu H, Zhu L, Wang Y, Yue X, Wang W, Sun Z, Jiang S, Chen Y, Wen Z*. Amide Proton Transfer Weighted MR Imaging for Predicting Meningioma Stiffness: A Feasibility Study. J Magn Reson Imaging. 2023 Apr;57(4):1071-1078.（2区，IF4.4）

[18] Jianbin Zhu, Yaoming Qu, Xianlong Wang, Chunxiu Jiang, Jianhua Mo, Jiandong Xi, Zhibo Wen*. Risk factors associated with pulmonary hemorrhage and hemoptysis following percutaneous CT-guided transthoracic lung core needle biopsy: a retrospective study of 1,090 cases. Quantitative imaging in medicine and surgery. 2020;10(5):1008-1020

[19]Jianping Liu1,2, Dongliang Cheng2, Yuting Liao3, Chun Luo2, Qiucheng Lei4, Xin Zhang5, Luyi Wang5, Zhibo Wen1#, Mingyong Gao2；Development of a magnetic resonance imaging-derived radiomics model to predict microvascular invasion in patients with hepatocellular carcinoma. Quant Imaging Med Surg 2023;13(6):3948-3961 | https://dx.doi.org/10.21037/qims-22-1011

[20] Xinzi Liu a , Yuxin Li Yongzhou Xu d a , Yixiang Mo , Jingyue Xue a b , Baoling Chen , Haitao Wen a c , Xusheng Hou , Xianlong Wang a b , Jianbin Zhu , Zhibo Wen; GABAergic imbalance in Parkinson’s disease–related depression determined with MEGA-PRESS. NeuroImage: Clinical Volume 43, 2024, 103641

[21]Xinyue Yang1#, Qing Qiu2#, Weirong Lu3, Bingmei Chen1, Minning Zhao1, Wen Liang1, Zhibo Wen1 Prediction of Kirsten rat sarcoma (KRAS) mutation in rectal cancer with amide proton transfer-weighted magnetic resonance imaging. Quant Imaging Med Surg 2024 | https://dx.doi.org/10.21037/qims-24-331

[22]Xiaochan Ou1, Jianbin Zhu1, Yaoming Qu1, Chengmei Wang1, Baiye Wang1, Xirui Xu2, Yanyu Wang1, Haitao Wen1, Andong Ma1, Xinzi Liu1, Xia Zou1 and Zhibo Wen1*Imaging features of sentinel lymph node mapped by multidetector-row computed tomography lymphography in predicting axillary lymph node metastasis.BMC Medical Imaging https://doi.org/10.1186/s12880-021-00722-0

[23]Andong Ma1, Xinran Yan1, Yaoming Qu1, Haitao Wen1, Xia Zou1, Xinzi Liu1, Mingjun Lu1, Jianhua Mo1 and Zhibo Wen1 Amide proton transfer weighted and diffusion weighted imaging based radiomics classification algorithm for predicting 1p/19q co-deletion status in low grade gliomas。BMC Medical Imaging https://doi.org/10.1186/s12880-024-01262-z

[24] Weicui Chen1 · Kaiyi Zheng2,3 · Wenjing Yuan1 · Ziqi Jia1 · Yuankui Wu4 · Xiaohui Duan5 · Wei Yang2,3 · Zhibo Wen6 · Liming Zhong2,3 · Xian Liu1 A CT‑based deep learning for segmenting tumors and predicting microsatellite instability in patients with colorectal cancers: a multicenter cohort study. La radiologia medica https://doi.org/10.1007/s11547-024-01909-5