黄裕立，南方医科大学第八附属医院心内科主任，广东省代谢障碍交叉医学精准防治与数字医疗工程技术研究中心常务副主任；佛山市心血管疾病精准诊疗工程技术研究中心主任，医学博士，主任医师，博士研究生导师，博士后合作导师，广东省杰出青年医学人才，广东省五一劳动奖章获得者。

学术任职：

        美国心脏病学院专家会员（FACC），澳大利亚乔治全球健康研究所高级荣誉研究员, 中华医学会心血管病学分会高血压学组组员；中国高血压联盟常务委员；中国研究型医院协会高血压专委会委员；中国医疗促进协会高血压分会青年委员；广东省医师协会高血压专业医师分会副主任委员；广东省精准医学会高血压分会副主任委员；广东省医疗行业协会心血管病管理分会副主任委员；广东省医疗行业协会心血管循证与实践管理分会副主任委员；广东省健康管理协会泛血管急重症专业委员会副主任委员；广东省医师协会心力衰竭医师分会常务委员；《Life research》副主编；《Journal of Geriatric Cardiology》，《Case Reports in Cardiology》, 《Journal of Interventional Cardiology》编委；《The innovation》青年编委；《中国循证医学杂志》编委；《欧洲心脏病杂志中文版》青年编委；《中华高血压杂志》青年编委；《中华细胞与干细胞杂志(电子版)》编委。著名国际SCI期刊BMJ，The Lancet Diabetes & Endocrinology, EHJ, Nature communication, International Journal of Epidemiology, Heart, American Journal of Kidney Disease 等近100个SCI审稿专家。

学术成绩简介：

        主持国家自然科学基金(2项)及广东省基础与应用基础研究重点项目等各级科研课题近10项。以第一/通讯作者发表SCI论文80余篇（article/review），包括BMJ（3篇），Neurology（2篇）等顶级刊物，单篇最高影响因子107.7，总影响因子超过700分。目前被引次数近7500次，个人H指数为41。

        共有15篇论文被2017年美国高血压指南，2018年欧洲高血压指南，2023年欧洲高血压指南，美国糖尿病指南（2019-2024连续6年），2019年加拿大糖尿病指南等国际权威指南和行业共识引用。7篇论文为ESI内科学高被引论文（前1%），5篇文章获得新闻发布形式推荐，9篇论文获得同期述评正面评价，1篇论文被收录为千名医学家（F1000）论文。1篇论文为FDA取消卡格列净致截肢风险升高黑框警告的重要依据。发表的多篇论文获得了Reuters Health，Medline，NEJM Journal Watch，Science world report ，CNN，Fox news，CBS news，NBC News，加拿大电视台，USA Today，U.S. News and World Report，哈佛健康通讯等国际著名学术媒体和公众媒体的广泛报道。

        在全球学者库中，位列2018-2022年全国心血管病学者学术影响力百强（第40位），2012-2021年全国心血管病学者学术影响力百强（第60位），两篇论文为2020年中国学者四大顶级期刊论文影响力百强（第42，49位），3篇论文为心血管领域论文影响力百强（第19，24，30位）。在2011-2021年10年期间，中国学者发表四大期刊论文影响力百强（第98位）。2020-2023年三次被评为《World Journal of Cardiology》（世界心脏病学杂志）封面学者。2025年度，入选美国斯坦福大学与爱思唯尔出版集团联合发布的2025年全球前2%顶尖科学家榜单（World’s Top 2% Scientists）。

       目前拥有国家发明专利2项，澳大利亚专利3项，南非发明专利1项，实用新型专利8项。软件著作权9项。

高血压病、代谢性心脏病和心力衰竭发病机制和治疗

发表论文（第一作者或通信作者SCI论文，含并列第一/并列通信）

一、Article/Review

        其中中科院小类一区论文12篇，包括BMJ（3篇），Neurology （2篇），AJKD，BMC med，Circ Heart Fail， Theranostics，Diabetologia等top期刊。总IF超700分。    

1) Wen W, Liu Z, Li L, Qiu F, Zhang H, Cao Y, Li J, Huang X, Huang Y*.Multimodal Mechanisms of Di (2-ethylhexyl) phthalate-Induced Cardiovascular-Kidney-Metabolic Syndrome: Integrating Epidemiology, Network Toxicology and Experimental Validation. Ecotoxicol Environ Saf. 2026 Jan 1:309:119515.

2) Hu B, He X, Sun Y, Liu T, Li F, Feng L, Huang Y*. Association of Oxidative Balance Score With All-Cause and Cardiovascular Mortality Among Hypertensive Adults. Rev Cardiovasc Med. 2025 Aug 15;26(8):37415.

3) Hao S, Zhang X, Li L, Mo L, Liu Y, Li J, Wang W, Wu J, Huang Y*. Developing and Externally Validating the Multivariable Prediction Model for White-Coat Hypertension.J Evid Based Med. 2025 Sep 9:e70064. 

4) Liu Y, Li J, Chen Y, Li L, Zhao L, Zhang X*, Huang Y*. Intravenous Iron in Heart Failure Patients With Iron Deficiency: A Meta-Analysis of Randomized Controlled Trials. J Evid Based Med. 2025 Aug 14:e70057.

5) Wu JD, Luo JJ, Li JH, Hao SL, Wang WL, Li W, Li WW, Huang GL, Liang GQ, Wen WX, He WM, Liu YG, Chen YX, Zhang XM, He ZP*, Huang Y*. Correlation of non-esterified fatty acids with acute coronary syndrome risk in young Chinese adults. Front Endocrinol (Lausanne). 2025 Jun 6;16:1479497. 

6) Chen P, Huang X, Wen W, Cao Y, Li W, Huang G, Huang Y*, Hu Y*, Ma T*. MiR214-3p Ameliorates Diabetic Cardiomyopathy by Inhibiting Ferroptosis. Cardiovasc Toxicol. 2025 2025 Jun;25(6):884-897.

7) Chen Y, Cao Y, Li L, Chen P, Zhang X, Hao S, Qiu M, Liu Y, Wu J, Chen Y, He Z*, Hu Y*, Huang Y*. The association between circulating palmitic acid levels and risk of premature coronary artery disease in Chinese patients: a case-control study. BMC Cardiovasc Disord. 2025 May 28;25(1):412.

8) Qiu F, Mai S, Li J, Cao Y, Wen W, Li L, Huang X, Huang Y*. Dose-response association between the intake of various subtypes of polyunsaturated fatty acids and depression. J Affect Disord. 2025 Mar 25;380:505-514.

9) Cao Y, Wen W, Zhang H, Li W, Huang G, Huang Y*. The association between visceral fat metabolic score and stroke: mediation by declining kidney function. Diabetol Metab Syndr. 2025 Feb 8;17(1):50.

10) Cao Y, Li L, Qiu F, Wen W, Zhang H, Chen Y, Cai X*, Huang Y*. Triglyceride-glucose index and mortality risks in Helicobacter pylori-infected patients: a national cohort study. BMC Infect Dis. 2025 Feb 6;25(1):180.

11) Xu T^#, Zhang H^#, Peng Z^#, Huang Y^#, Zhan Q, Ma Z, Zeng X, Liu C, Zeng Q, Dong Y, Xu D. The addition of alpha-ketoglutarate to NT-proBNP improves the prediction of long-term all-cause mortality in acute heart failure patients. Ann Med. 2025 Dec;57(1):2477827. doi: 10.1080/07853890.2025.2477827.

12) Zhu H, Li J, Li L, Liang X, Huang C, Cai X, Huang Y*, Huo Y*. Prevalence and Cardio-Renal Comorbidities of Masked Hypertension: A Meta-Analysis. J Evid Based Med. 2024 Dec;17(4):833-842.

13) Wen W, Cao Y, Chen P, Li J, Li W, Huang G, Zheng H, Zhu X, Zhang H, Chen Y, Huang X*, Hu Y*, Huang Y*. A reliable strategy for establishment of an animal model of diabetic cardiomyopathy: Induction by a high-fat diet combined with single or multiple injections of low-dose streptozotocin. Life Sci. 2024 Dec 1;358:123161.

14) Chen S, Guan S, Yan Z, Ouyang F, Li S, Liu L, Zuo L*, Huang Y*, Zhong J*. Prognostic value of red blood cell distribution width-to-albumin ratio in ICU patients with coronary heart disease and diabetes mellitus. Front Endocrinol (Lausanne). 2024 Sep 25;15:1359345.

15) Chen P, Huang X, Li W, Wen W, Cao Y, Li J, Huang Y*, Hu Y*. Myeloid-derived growth factor in diseases: structure, function and mechanisms. Mol Med. 2024 Jul 19;30(1):103.

16) Zheng H, Li W, Huang G, Zhu H, Wen W, Liu X, Sun L, Ma T, Huang X*, Hu Y*, Huang Y*. Secreted frizzled-related protein 2 ameliorates diabetic cardiomyopathy by activating mitophagy. Biochim Biophys Acta Mol Basis Dis. 2024 Feb;1870(2):166989.

17) Wu W, Ma W, Yuan S, Feng A, Li L, Zheng H, Li S, He N, Huang Y*, Lyu J*. Associations of Unhealthy Lifestyle and Nonalcoholic Fatty Liver Disease With Cardiovascular Healthy Outcomes. J Am Heart Assoc. 2023 Dec 5;12(23):e031440.

18) Zhang X, Yang S, Hao S, Li J, Qiu M, Chen H*, Huang Y*. Myocardial fibrosis and prognosis in heart failure with preserved ejection fraction: a pooled analysis of 12 cohort studies. Eur Radiol. 2023 Sep 2. doi: 10.1007/s00330-023-10218-w.

19) Wen W, Zheng H, Li W, Huang G, Chen P, Zhu X, Cao Y, Li J, Huang X, Huang Y*. Transcription factor EB: A potential integrated network regulator in metabolic-associated cardiac injury. Metabolism. 2023 Oct;147:155662.

20) Sun L, Zheng H, Qiu M, Hao S, Liu X, Zhu X, Cai X, Huang Y*. Helicobacter pylori infection and risk of cardiovascular disease. Helicobacter. 2023 Jun;28(3):e12967. 

21) Qiu M, Li J, Hao S, Zheng H, Zhang X, Zhu H, Zhu X, Hu Y, Cai X, Huang Y*. Non-alcoholic fatty liver disease is associated with a worse prognosis in patients with heart failure: A pool analysis. Front Endocrinol (Lausanne). 2023 Apr 20;14:1167608. 

22) Liu X, Zhu H, Zheng H, Sun L, Qiu M, Huang Y*. Stains therapy and the risk of all bleeding and intracranial hemorrhage: A meta-analysis of randomized controlled studies. J Evid Based Med. 2022 Dec;15(4):373-384. 

23) Liu X, Sun L, Wen W, Qiu M, Luo J, Li W, Hao S, He M, Wu J, Hu Y, Huang Y*. Association between the ratio of serum eicosapentaenoic acid to arachidonic acid and risk of coronary artery disease in young Chinese patients. Front Nutr. 2022 Nov 3;9:1019058. 

24) Mai S, Zhu H, Li M, Zeng Y, Zhang Y, Huo Y, Pan XF, Huang Y*. Blood pressure measurement in the elderly with atrial fibrillation: an observational study comparing different noninvasive sphygmomanometers. Ther Adv Chronic Dis. 2022 Nov 14;13:20406223221137040 

25) Zhu H, Zheng H, Liang X, Huang C, Sun L, Liu X, Qiu M, Mai W, Huang Y*. Prevalence and Related Factors of White Coat Hypertension and Masked Hypertension in Shunde District, Southern China. Front Physiol. 2022;13:936750. 

26) Ma W, Wu W, Wen W, Xu F, Han D, Lyu J*, Huang Y*. Association of NAFLD with cardiovascular disease and all-cause mortality: a large-scale prospective cohort study based on UK Biobank. Ther Adv Chronic Dis. 2022 Sep 20;13:20406223221122478

27) Zheng S, Qiu M, Wu JHY, Pan XF, Liu X, Sun L, Zhu H, Wu J, Huang Y*. Long-chain omega-3 polyunsaturated fatty acids and the risk of heart failure. Ther Adv Chronic Dis. 2022 Mar 18;13:20406223221081616. 

28) Li W, Wen W, Xie D, Qiu M, Cai X, Zheng S, Huang Y*. Association between non-alcoholic fatty liver disease and risk of incident heart failure: a meta-analysis of observational studies. Ther Adv Chronic Dis. 2022;13:20406223221119626. 

29) Wu J, Qiu M, Sun L, Wen J, Liang DL, Zheng S, Huang Y*. α-Linolenic Acid and Risk of Heart Failure: A Meta-Analysis. Front Cardiovasc Med. 2022 Jan 4;8:788452. 

30) Ma T, Huang X, Zheng H, Huang G, Li W, Liu X, Liang J, Cao Y, Hu Y, Huang Y*. SFRP2 Improves Mitochondrial Dynamics and Mitochondrial Biogenesis, Oxidative Stress, and Apoptosis in Diabetic Cardiomyopathy. Oxid Med Cell Longev. 2021 Nov 8;2021:9265016. 

31) Zhu H, Zheng H, Xu T, Liu X, Liu X, Sun L, Pan XF, Mai W, Cai X, Huang Y. Effects of statins in primary and secondary prevention for venous thromboembolism events: A meta analysis. Vascul Pharmacol. 2022 Feb;142:106931.

32) Zheng H, Zhu H, Liu X, Huang X, Huang A, Huang Y*. Mitophagy in Diabetic Cardiomyopathy: Roles and Mechanisms. Front Cell Dev Biol. 2021 Sep 27;9:750382. 

33) Xu T, Huang Y, Liu Z, Bai Y, Ma Z, Cai X, Zhang Y, Zhang J. Heart Failure Is Associated with Increased Risk of Long-Term Venous Thromboembolism. Korean Circ J. 2021 Sep;51(9):766-780.

34) Mai L, Wen W, Qiu M, Liu X, Sun L, Zheng H, Cai X, Huang Y*. Association between prediabetes and adverse outcomes in heart failure. Diabetes Obes Metab. 2022 Nov;23(11):2476-2483. 

35) Cai X, Sun L, Liu X, Zhu H, Zhang Y, Zheng S, Huang Y*. Non-alcoholic fatty liver disease is associated with increased risk of chronic kidney disease. Therapeutic Advances in Chronic Disease. 2021; 12:20406223211024361

36) Tao J, Chen H, Wang YJ, Qiu JX, Meng QQ, Zou RJ, Li L, Huang JG, Zhao ZK, Huang YL*, Zhang HF*, Zheng JM*. Ketogenic Diet Suppressed T-Regulatory Cells and Promoted Cardiac Fibrosis via Reducing Mitochondria-Associated Membranes and Inhibiting Mitochondrial Function. Oxid Med Cell Longev. 2021 Apr 19;2021:5512322. 

37) Cai X, Liu X, Sun L, He Y, Zheng S, Zhang Y, Huang Y*. Prediabetes and the risk of heart failure: A meta-analysis. Diabetes Obes Metab. Diabetes Obes Metab. 2021 Aug;23(8):1746-1753

38) Wu J, Liang J, Li M, Lin M, Mai L, Huang X, Liang J, Hu Y*, Huang Y*. Modulation of miRNAs by vitamin C in H2O2‑exposed human umbilical vein endothelial cells. Int J Mol Med. 2020 Dec;46(6):2150-2160. 

39) Li W, Huang A, Zhu H, Liu X, Huang X, Huang Y, Cai X, Lu J, Huang Y. Gut microbiota-derived trimethylamine N-oxide is associated with poor prognosis in patients with heart failure. Med J Aust. 2020;213(8):374-379. 

40) Huang Y, Zheng H, Tan K, Sun X, Ye J*, Zhang Y*. Circulating metabolomics profiling reveals novel pathways associated with cognitive decline in patients with hypertension. Ther Adv Neurol Disord. 2020 Sep 3;13:1756286420947973.

41) Wu J, Zheng H, Liu X, Chen P, Zhang Y, Luo J, Kuang J, Li J, Yang Y, Ma T, Yang Y, Huang X, Liang G, Liang D, Hu Y, Wu JHY, Arnott C, Mai W*, Huang Y*. Prognostic Value of Secreted Frizzled-Related Protein 5 in Heart Failure Patients With and Without Type 2 Diabetes Mellitus. Circ Heart Fail. 2020 Sep;13(9):e007054. 

42) Cai X, Zhang Y, Li M, Wu JH, Mai L, Li J, Yang Y, Hu Y, Huang Y*. Association between prediabetes and risk of all cause mortality and cardiovascular disease: updated meta-analysis. BMJ. 2020 Jul 15;370:m2297. 

43) Zhu H, Liang X, Pan XF, Huang C, Kuang J, Lv W, Zeng Q, Mai W, Huang Y*. A prospective cohort study of home blood pressure monitoring based on an intelligent cloud platform (the HBPM-iCloud study): rationale and design. Ther Adv Chronic Dis. 2020 Jun 10;11:2040622320933108. 

44) Yang Y, Guo S*, Huang Z, Deng C, Chen L, Zhou G, Jian Z, He R, Huang Z, Yao Y, Lu J, Hua Z, Huang Y*. Decreased Mortality with Beta-Blocker Therapy in HFpEF Patients Associated with Atrial Fibrillation. Cardiol Res Pract. 2020 May 13;2020:3059864. 

45) Yang S, Chen H, Tan K, Cai F, Du Y, Lv W, Hu Q, Hu Y*, Huang Y*. Secreted Frizzled-Related Protein 2 and Extracellular Volume Fraction in Patients with Heart Failure. Oxid Med Cell Longev. 2020 May 6;2020:2563508. 

46) Arnott C^#, Huang Y^#, Neuen B, Di Tanna GL, Cannon CP, Oh R, Edwards R, Kavalam M, Rosenthal N, Perkovic V, Jardine M, Mahaffey K, Neal B. The effect of canagliflozin on amputation risk in the CANVAS Program and the CREDENCE trial. Diabetes Obes Metab. 2020 Oct;22(10):1753-1766. 

47) Yang Y, Li W, Zhu H, Pan XF, Hu Y, Arnott C, Mai W, Cai X, Huang Y*. Prognosis of unrecognised myocardial infarction determined by electrocardiography or cardiac magnetic resonance imaging: systematic review and meta-analysis. BMJ. 2020 May 7;369:m1184. 

48) Huang Y^#, Dai M^#, Deng Z^#, Huang X, Li H, Bai Y, Yan C, Zhan Q, Zeng Q, Ouyang P, Xu D. Clustering of risk factors and the risk of new-onset hypertension defined by the 2017 ACC/AHA Hypertension Guideline. J Hum Hypertens. 2020 May;34(5):372-377. 

49) Zheng S, Zheng H, Huang A, Mai L, Huang X, Hu Y, Huang Y*. Piwi-interacting RNAs play a role in vitamin C-mediated effects on endothelial aging. Int J Med Sci. 2020 Mar 26;17(7):946-952.

50) Cai X, Zheng S, Liu Y, Zhang Y, Lu J, Huang Y. Nonalcoholic fatty liver disease is associated with increased risk of atrial fibrillation. Liver Int. 2020 Jul;40(7):1594-1600. 

51) Huang A, Zheng H, Wu Z, Chen M*, Huang Y*. Circular RNA-protein interactions: functions, mechanisms, and identification. Theranostics. 2020 Feb 10;10(8):3503-3517. 

52) Wu Y, Liu X, Zheng H, Zhu H, Mai W, Huang X, Huang Y*. Multiple Roles of sFRP2 in Cardiac Development and Cardiovascular Disease. Int J Biol Sci. 2020 Jan 14;16(5):730-738. 

53) Huang A, Huang Y*. Role of Sfrps in cardiovascular disease. Ther Adv Chronic Dis. 2020 Jan 28;11:2040622320901990. 

54) Zhu H, Zheng H, Liu X, Mai W, Huang Y*. Clinical applications for out-of-office blood pressure monitoring. Ther Adv Chronic Dis. 2020 Jan 20;11:2040622320901660. 

55) Lin M, Liu X, Zheng H, Huang X, Wu Y, Huang A, Zhu H, Hu Y, Mai W, Huang Y*. IGF-1 enhances BMSC viability, migration, and anti-apoptosis in myocardial infarction via secreted frizzled-related protein 2 pathway. Stem Cell Res Ther. 2020 Jan 9;11(1):22. 

56) Liu Y, Wang S, Kan J, Zhang J, Zhou L, Huang Y*, Zhang Y*. Chinese Herbal Medicine Interventions in Neurological Disorder Therapeutics by Regulating Glutamate Signaling. Curr Neuropharmacol. 2020;18(4):260-276

57) Mai L, Wu Y, Luo J, Liu X, Zhu H, Zheng H, Liang G, Zhang Y, Huang Y. A retrospective cohort study of oral anticoagulant treatment in patients with acute coronary syndrome and atrial fibrillation. BMJ Open. 2019 Sep 17;9(9):e031180.

58) Hu G, Liu D, Tong H, Huang W, Hu Y*, Huang Y*. Lipoprotein-Associated Phospholipase A2 Activity and Mass as Independent Risk Factor of Stroke: A Meta-Analysis. Biomed Res Int. 2019 May 20;2019:8642784.

59) Xu T^#, Huang Y^#, Zhou H, Bai Y, Huang X, Hu Y, Xu D, Zhang Y, Zhang J.β-blockers and risk of all-cause mortality in patients with chronic heart failure and atrial fibrillation-a meta-analysis. BMC Cardiovasc Disord. 2019 Jun 3;19(1):135. 

60) Huang Y^#, Deng Z^#, Se Z, Bai Y, Yan C, Zhan Q, Zeng Q, Ouyang P, Dai M, Xu D. Combined impact of risk factors on the subsequent development of hypertension. J Hypertens. 2019 Apr;37(4):696-701.

61) Huang Y, Luo J, Liu X, Wu Y, Yang Y, Li W, Lv W, Hu Y. Gamma-Glutamyltransferase and Risk of Acute Coronary Syndrome in Young Chinese Patients: A Case-Control Study. Dis Markers. 2018 Sep 2;2018:2429160. 

62) Huang Y, Wu Y, Yang Y, Li W, Lu J, Hu Y. Lipoprotein-associated phospholipase A2 and oxidized low-density lipoprotein in young patients with acute coronary syndrome in China. Sci Rep. 2017 Nov 23;7(1):16092. 

63) Huang Y, Zhou H, Wu Y, Yang Y, Li W, Lu J, Hu Y. Soluble Urokinase Plasminogen Activator Receptor and the Risk of Coronary Artery Disease in Young Chinese Patients. Dis Markers. 2017:4719403. 

64) Huang Y^#, Huang W^#, Mai W, Cai X, An D, Liu Z, Huang H, Zeng J, Hu Y, Xu D. White-coat hypertension is a risk factor for cardiovascular diseases and total mortality. J Hypertens. 2017 Apr;35(4):677-688.

65) Huang Y, Cai X, Mai W, Li M, Hu Y. Association between prediabetes and risk of cardiovascular disease and all cause mortality: systematic review and meta-analysis. BMJ. 2016 Nov 23;355:i5953. 

66) Xu T, Liu W, Cai X, Ding J, Tang H, Huang Y*, Hu Y*. Risk of Coronary Heart Disease in Different Criterion of Impaired Fasting Glucose: A Meta-Analysis. Medicine (Baltimore). 2015 Oct;94(40):e1740. 

67) Xu S^#, Huang Y^#, Xiao J, Zhu W, Wang L, Tang H, Hu Y, Liu T. The association between job strain and coronary heart disease: A meta-analysis of prospective cohort studies. Ann Med. 2015 Sep;47(6):512-518.

68) Yang Y, Bi M, Xiao L, Chen Q, Chen W, Li W, Wu Y, Hu Y*, Huang Y*. Perceived stress status and sympathetic nervous system activation in young male patients with coronary artery disease in China. Eur J Intern Med. 2015;26(9):726-730. 

69) Chen Y, Cai X, Huang W, Wu Y, Huang Y*, Hu Y*. Increased All-Cause Mortality Associated With Digoxin Therapy in Patients With Atrial Fibrillation: An Updated Meta-Analysis. Medicine (Baltimore). 2015 Dec;94(52):e2409. 

70) Huang Y^#, Xu S^#, Hua J, Zhu D, Liu C, Hu Y, Liu T*, Xu D*. Association between job strain and risk of incident stroke: A meta-analysis. Neurology. 2015 Nov 10;85(19):1648-54.

71) Huang Y, Cai X, Liu C, Zhu D, Hua J, Hu Y, Peng J, Xu D. Prehypertension and the risk of coronary heart disease in Asian and Western populations: a meta-analysis. J Am Heart Assoc. 2015;19;4(2). pii: e001519 

72) Huang Y, Cai X, Li Y, Su L, Mai W, Wang S, Hu Y, Wu Y, Xu D. Prehypertension and the risk of stroke: A meta-analysis. Neurology. 2014;82(13):1153-61

73) Huang Y, Cai X, Zhang J, Mai W, Wang S, Hu Y, Ren H, Xu D. Prehypertension and Incidence of ESRD: A Systematic Review and Meta-analysis. Am J Kidney Dis. 2014;63(1):76-83.

74) Huang Y, Su L, Cai X, Mai W, Wang S, Hu Y, Wu Y, Tang H, Xu D. Association of all-cause and cardiovascular mortality with prehypertension: A meta-analysis. Am Heart J. 2014；167(2):160-168.e1. 

75) Huang Y^#, Qiu W^#, Liu C, Zhu D, Hua J, Cai X, Wu Y, Hu Y, Xu D. Prevalence and risk factors associated with prehypertension in Shunde District, southern China. BMJ Open. 2014;4(11):e006551  

76) Huang Y, Cai X, Qiu M, Chen P, Tang H, Hu Y*, Huang Y*. Prediabetes and the risk of cancer: a meta-analysis. Diabetologia. 2014;57(11):2261-9. 

77) Huang Y, Cai X, Chen P, Mai W, Tang H, Huang Y*, Hu Y*. Associations of prediabetes with all-cause and cardiovascular mortality: A meta-analysis. Ann Med. 2014;46(8):684-92 

78) Du Z^#, Shen A^#, Huang Y^#, Su L, Lai W, Wang P, Xie Z, Xie Z, Zeng Q, Ren H, Xu D. 1H-NMR-based metabolic analysis of human serum reveals novel markers of myocardial energy expenditure in heart failure patients. Plos One. 2014;9(2):e88102.  

79) Huang Y, Wang S, Cai X, Mai W, Hu Y, Tang H, Xu D. Prehypertension and incidence of cardiovascular disease: a meta-analysis. BMC Med. 2013 ;11:177. 

80) Huang Y, Cai X, Song X, Tang H, Huang Y, Xie S, Hu Y. Steroids for preventing recurrence of acute severe migraine headaches: a meta-analysis. Eur J Neurol. 2013;20(8):1184-1190. 

81) Wu Y^#, Huang Y^#, Hu Y, Zhong J, He Z, Li W, Yang Y, Xu D, Wu S. Hyperhomocysteinemia is an independent risk factor in young patients with coronary artery disease in southern China. Herz. 2013;38(7):779-84. 

82) Huang YL, Kuang J, Hu YZ, Song YB, Qiu RF, Mai WY. Bone marrow stromal cell transplantation combined with angiotensin-converting enzyme inhibitor treatment in rat with acute myocardial infarction and the role of insulin-like growth factor-1. Cytotherapy. 2012. 14(5): 563-569. 

83) Huang Y, Qiu R, Mai W, Kuang J, Cai X, Dong Y, Hu Y, Song Y, Cai A, Jiang Z. Effects of insulin-like growth factor-1 on the properties of mesenchymal stem cells in vitro. J Zhejiang Univ Sci B. 2012. 13(1): 20-8.

84) Huang Y, Mai W, Cai X, Hu Y, Song Y, Qiu R, Wu Y, Kuang J. The effect of zolpidem on sleep quality, stress status, and nondipping hypertension. Sleep Med. 2012. 13(3): 263-268.

85) Huang Y, Hu Y, Mai W, Cai X, Song Y, Wu Y, Dong Y, Huang H, He Z, Li W, Yang Y, Rao S. Plasma oxidized low-density lipoprotein is an independent risk factor in young patients with coronary artery disease. Dis Markers. 2011. 31(5): 295-301. 

86) Huang Y, Mai W, Hu Y, Wu Y, Song Y, Qiu R, Dong Y, Kuang J. Poor sleep quality, stress status, and sympathetic nervous system activation in nondipping hypertension. Blood Press Monit. 2011. 16(3): 117-123. 

87) Huang Y, Song Y, Mai W, Hu Y, Cai X, Wu Y, Qiu R, Kuang J. Association of N-terminal pro brain natriuretic peptide and impaired aortic elastic property in hypertensive patients. Clin Chim Acta. 2011. 412(23-24): 2272-2276. 

二、Editorial/Letter

1) Huang Y, Ye J, Zhang Y. Early-Life Chemical Exposures and Blood Pressure: Is Mineralocorticoid Signaling a Key Player? J Am Coll Cardiol 2020;75(2):242.

2) Cai X, Zheng S, Zhang Y, Huang Y*. Helicobacter pylori, non-alcoholic liver disease and atrial fibrillation: Is there a link? Liver Int. 2020 Aug;40(8):2037-2038.

3) Huang Y, Kuang J, Mai W. Blood Pressure Indexes Associated With Mortality and Cardiovascular Outcomes. JAMA 2019;322(23):2342-2343.

4) Tan J, Mai L, Zhang Y, Wu Y, Huang Y*. What Is Important for Digoxin Treatment in Patients With Heart Failure. J Am Coll Cardiol 2019;74(22):2827.

5) Huang Y, Ouyang H, Lin M, Zhang Y, He Y. The challenge of risk stratification in Takotsubo stress cardiomyopathy. Int J Cardiol 2019;279:31.

6) Li J, Liu X, Zheng S, Huang Y. Use of Oral Anticoagulation for Patients With Atrial Fibrillation and End-stage Renal Disease: What Is Needed Nowadays? Rev Esp Cardiol (Engl Ed) 2019;72(1):96-97.

7) Li W, Mai L, Cai X, Li M, Huang Y. Bivalirudin infusion in patients with acute coronary syndrome after stenting. Expert Opin Pharmacother 2019;20(11):1413-1414.

8) Huang Y, Mai L, Zhang Y, Cai X. Optimal Dose of Rivaroxaban in Asians With Atrial Fibrillation: Further Studies Are Warranted. J Am Coll Cardiol 2018;72(21):2681-2682.

9) Huang Y, Li M. Prediabetes definitions and clinical outcomes. Lancet Diabetes Endocrinol 2017;5(2):93.

10) Huang Y, Huang W, Hu Y. Is White-Coat Hypertension Associated With Risk of Cardiovascular Diseases? J Am Coll Cardiol 2017;69(23):2880.

11) Huang Y, Li M, Huang W. Hypertension Treatment in the Elderly: Individualized Target or Intensive Blood Pressure Lowering? J Am Coll Cardiol 2017;70(4):509-510.

12) Huang Y, Mai L, Cai X, Hu Y, Mai W. Stem cell therapy for heart disease-Meta-analysis may be misleading. Int J Cardiol 2016;203:351-2.

13) Xiao L, Ouyang H, Su Q, Huang Y. Angiotensin-converting enzyme inhibitors and angiotensin II receptor blockers on prevention of stroke: Which one is better? Int J Cardiol 2016;223:56-57.

14) Huang Y, Huang W, Hu Y. Digoxin in patients with atrial fibrillation and heart failure: A risk factor or a marker of increased mortality? Int J Cardiol 2016;206:171-2.

15) Chen Y, Huang W, Huang Y, Hu Y. Beta-blockers treatment in heart failure with atrial fibrillation--Who should we believe? Int J Cardiol 2016;203:60-1.

16) Huang Y, Mai W, Hu Y. New Insights for Mesenchymal Stem Cells in the Treatment of Ischemic Cardiomyopathy. Cell Transplant 2015;24(9):1913-4.

17) Xu T, Huang Y. Prehypertension-new insights for health risks. Nat Rev Cardiol 2015;12(7):440.

18) Huang YL, Tang HF, Hu YZ. Stem cells for cardiac repair--should we be cautious? Nat Rev Cardiol 2014;11(10):615.

19) Huang YL, Huang Y, Wu YX. Statins for primary prevention: identifying low-risk individuals. Nat Rev Cardiol 2013;10(9):547

20) Huang Y, Cai X, Hu Y. The important role of microRNAs in lipid metabolism. Metabolism 2013;62(3):e1-2.

21) Huang Y, Wu Y, Hu Y. Correlation of oxidized low-density lipoprotein and C-reactive protein in patients with coronary artery disease. Cell Biochem Biophys 2013;65(2):285-6.

22) Huang Y, Hu Y. Lipid-lowering agents in chronic kidney disease: do fibrates have a role? Nat Rev Cardiol 2013;10(9):547.

23) Huang Y, Mai W, Wu Y. Importance of multimodality imaging to guide therapy in stable CAD. Nat Rev Cardiol 2012;9(8):438.

24) Huang Y, Hu Y, Mai W. Stress and sleep disturbance--a connection in CVD. Nat Rev Cardiol 2012;9(10):598

25) Huang Y, Mai W, Hu Y. Relationship between sleep quality and the level and pattern of BP. Nat Rev Cardiol 2012;9(7):429

26) Huang Y, Mai W, Hu Y. In response: from pathophysiology to treatment: the importance of sympathetic nervous system activation in nondipping hypertension. Blood Press Monit 2011;16(6):307-9.

三、Meeting Abstract：均为心血管病学顶级学术会议论文，包括ACC，AHA等

1) Huang Y, Zheng S, Zhu H, Lu J, Li W, Hu Y. Gut Microbe-Generated Metabolite Trimethylamine-N-Oxide And Risk Of Major Adverse Cardiovascular Events In Patients With Heart Failure. J Am Coll Cardiol. 2020;75:834.

2) Huang Y, Huang A, Wu Y, Luo J, Lv W, Hu Y. Decreased Serum Insulin-Like Growth Factor-1 is Associated With Higher Myocardial Energy Expenditure in Patients With Diabetes and Heart Failure. Circulation. 2018;138:1

3) Huang Y, Wu Y, Yang Y, Li W, Lu J, Hu Y. Gamma-Glutamyl Transferase And Oxidized Low-Density Lipoprotein In Premature Coronary Artery Disease In Chinese. J Am Coll Cardiol. 2018;71:110.

4) Huang Y, Wu Y, Hu Y, Hu G, Huang W. Anti-Fibrotic Effects of Neuregulin-1 Beta Via Suppression Of Endothelial To Mesenchymal Transition In Diabetic Cardiomyopathy. J Am Coll Cardiol. 2018;71:805.

5) Huang Y, Cai X, Zhu D, Liu C, Hu Y, Xu D. Prehypertension increased the Risk of Coronary Heart Disease: A Meta-analysis. J Am Coll Cardiol. 2014;64:C100.

6) Huang Y, Qiu W, Hu Y, Xu D. Prevalence and Risk Factors Associated with Prehypertension in Shunde District. J Am Coll Cardiol. 2014;64:C96-C97.