目录
关闭
更新日期：2024年10月16日
姓 名 黄裕立 性 别 男
民 族 汉族 导师层次 博士导师
技术职称 主任医师 导师类型 学术&专业型
最后学历 硕士研究生毕业 最后学位 临床医学博士专业学位
行政职务 主任 Email hyuli821@163.com
工作单位 南方医科大学第八附属医院（佛山市顺德区第一人民医院） 邮政编码 528308
个人简介

黄裕立，南方医科大学顺德医院心内科主任，佛山市心血管疾病精准诊疗工程技术研究中心主任，医学博士，主任医师，博士研究生导师，博士后合作导师，广东省杰出青年医学人才，广东省五一劳动奖章获得者。

学术任职：

        澳大利亚乔治全球健康研究所高级荣誉研究员, 中华医学会心血管病学分会高血压学组组员；中国研究型医院协会高血压专委会委员；中国医疗促进协会高血压分会青年委员；广东省健康管理协会泛血管急重症专业委员会副主任委员；广东省医师协会心力衰竭医师分会常务委员；广东省精准医学会高血压分会常务委员；广东省医师协会高血压分会委员；广东省医学会心血管分会青年委员；广东省医师协会心血管内科医师分会青年专业组组员；《Life research》副主编；《Journal of Geriatric Cardiology》，《Case Reports in Cardiology》, 《Journal of Interventional Cardiology》编委；《The innovation》青年编委；中国循证医学杂志》编委；《欧洲心脏病杂志中文版》青年编委；《中华高血压杂志》青年编委；《中华细胞与干细胞杂志(电子版)》编委。著名国际SCI期刊BMJ，The Lancet Diabetes & Endocrinology, EHJ, International Journal of Epidemiology, Heart, American Journal of Kidney Disease 等近80余个SCI审稿专家。

学术成绩简介：

        主持国家自然科学基金(2项)及广东省基础与应用基础研究重点项目等各级科研课题近10项。以第一/通讯作者发表SCI论文60余篇（article/review），包括BMJ（3篇），Neurology（2篇）等顶级刊物，单篇最高影响因子105.7，总影响因子超过620分。目前被引次数近5000次，个人H指数为33。

        共有10篇论文被2017年美国高血压指南，2018年欧洲高血压指南，美国糖尿病指南（2019-2022连续4年），2019年加拿大糖尿病指南等国际权威指南和行业共识引用。7篇论文为ESI内科学高被引论文（前1%），5篇文章获得新闻发布形式推荐，9篇论文获得同期述评正面评价，1篇论文被收录为千名医学家（F1000）论文。1篇论文为FDA取消卡格列净致截肢风险升高黑框警告的重要依据。发表的多篇论文获得了Reuters Health，Medline，NEJM Journal Watch，Science world report ，CNN，Fox news，CBS news，NBC News，加拿大电视台，USA Today，U.S. News and World Report，哈佛健康通讯等国际著名学术媒体和公众媒体的广泛报道。

        在全球学者库中，位列2012-2021年全国心血管病学者学术影响力百强（第60位），两篇论文为2020年中国学者四大顶级期刊论文影响力百强（第42，49位），3篇论文为心血管领域论文影响力百强（第19，24，30位）。在2011-2021年10年期间，中国学者发表四大期刊论文影响力百强（第98位）。2020-2023年三次被评为《World Journal of Cardiology》（世界心脏病学杂志）封面学者。

        目前拥有国家发明专利2项，澳大利亚专利3项，实用新型专利8项。软件著作权9项。

 

 

研究领域

高血压病；冠心病；心力衰竭；心脏代谢性疾病

个人成果
  1. Zhu H, Zheng H, Liang X, Huang C, Sun L, Liu X, Qiu M, Mai W, Huang Y*. Prevalence and Related Factors of White Coat Hypertension and Masked Hypertension in Shunde District, Southern China. Front Physiol. 2022;13:936750. （2021 年IF 4.755，JCR 1区，中科院小类2区）
  2. Zheng S, Qiu M, Wu JHY, Pan XF, Liu X, Sun L, Zhu H, Wu J, Huang Y*. Long-chain omega-3 polyunsaturated fatty acids and the risk of heart failure. Ther Adv Chronic Dis. 2022 Mar 18;13:20406223221081616. （2021 年IF 4.97，JCR 1区，中科院小类2区）
  3. Li W, Wen W, Xie D, Qiu M, Cai X, Zheng S, Huang Y*. Association between non-alcoholic fatty liver disease and risk of incident heart failure: a meta-analysis of observational studies. Ther Adv Chronic Dis. 2022;13:20406223221119626. 2021 年IF 4.97，JCR 1区，中科院小类2区）
  4. Wu J, Qiu M, Sun L, Wen J, Liang DL, Zheng S, Huang Y*. α-Linolenic Acid and Risk of Heart Failure: A Meta-Analysis. Front Cardiovasc Med. 2022 Jan 4;8:788452. (2021 年IF 5.846，JCR 2区，中科院小类3区)
  5. Ma T, Huang X, Zheng H, Huang G, Li W, Liu X, Liang J, Cao Y, Hu Y, Huang Y*. SFRP2 Improves Mitochondrial Dynamics and Mitochondrial Biogenesis, Oxidative Stress, and Apoptosis in Diabetic Cardiomyopathy. Oxid Med Cell Longev. 2021 Nov 8;2021:9265016. (2021 年IF 7.31，JCR2区，中科院小类3区)
  6. Zhu H, Zheng H, Xu T, Liu X, Liu X, Sun L, Pan XF, Mai W, Cai X, Huang Y. Effects of statins in primary and secondary prevention for venous thromboembolism events: A meta analysis. Vascul Pharmacol. 2022 Feb;142:106931. (2021 年IF 5.738，JCR2区，中科院小类2区)
  7. Zheng H, Zhu H, Liu X, Huang X, Huang A, Huang Y*. Mitophagy in Diabetic Cardiomyopathy: Roles and Mechanisms. Front Cell Dev Biol. 2021 Sep 27;9:750382. (2021 年IF 6.081，JCR 2区，中科院小类2区)
  8. Xu T, Huang Y, Liu Z, Bai Y, Ma Z, Cai X, Zhang Y, Zhang J. Heart Failure Is Associated with Increased Risk of Long-Term Venous Thromboembolism. Korean Circ J. 2021 Sep;51(9):766-780. (2021 年IF 3.101，JCR 2区，中科院小类3区)
  9. Mai L, Wen W, Qiu M, Liu X, Sun L, Zheng H, Cai X, Huang Y*. Association between prediabetes and adverse outcomes in heart failure. Diabetes Obes Metab. 2021 Nov;23(11):2476-2483. (2021 年IF 6.408，JCR 1区，中科院小类2区)
  10. Cai X, Sun L, Liu X, Zhu H, Zhang Y, Zheng S, Huang Y*. Non-alcoholic fatty liver disease is associated with increased risk of chronic kidney disease. Therapeutic Advances in Chronic Disease. 2021; 12:20406223211024361 (2021 年IF 4.97，JCR 1区，中科院小类2区)
  11. Tao J, Chen H, Wang YJ, Qiu JX, Meng QQ, Zou RJ, Li L, Huang JG, Zhao ZK, Huang YL*, Zhang HF*, Zheng JM*. Ketogenic Diet Suppressed T-Regulatory Cells and Promoted Cardiac Fibrosis via Reducing Mitochondria-Associated Membranes and Inhibiting Mitochondrial Function. Oxid Med Cell Longev. 2021 Apr 19;2021:5512322. (2021 年IF 7.31，JCR2区，中科院小类3区)
  12. Cai X, Liu X, Sun L, He Y, Zheng S, Zhang Y, Huang Y*. Prediabetes and the risk of heart failure: A meta-analysis. Diabetes Obes Metab. Diabetes Obes Metab. 2021 Aug;23(8):1746-1753 (2021 年IF 6.408，JCR 1区，中科院小类2区)
  13. Wu J, Liang J, Li M, Lin M, Mai L, Huang X, Liang J, Hu Y*, Huang Y*. Modulation of miRNAs by vitamin C in H2O2‑exposed human umbilical vein endothelial cells. Int J Mol Med. 2020 Dec;46(6):2150-2160. (2021 年IF 5.314，JCR 2区，中科院小类3区)
  14. Li W, Huang A, Zhu H, Liu X, Huang X, Huang Y, Cai X, Lu J, Huang Y. Gut microbiota-derived trimethylamine N-oxide is associated with poor prognosis in patients with heart failure. Med J Aust. 2020;213(8):374-379. (2021 年IF 12.776，JCR 1区，中科院小类2区)
  15. Huang Y, Zheng H, Tan K, Sun X, Ye J*, Zhang Y*. Circulating metabolomics profiling reveals novel pathways associated with cognitive decline in patients with hypertension. Ther Adv Neurol Disord. 2020 Sep 3;13:1756286420947973. (2021 年IF 6.43，JCR 1区，中科院小类2区)
  16. Wu J, Zheng H, Liu X, Chen P, Zhang Y, Luo J, Kuang J, Li J, Yang Y, Ma T, Yang Y, Huang X, Liang G, Liang D, Hu Y, Wu JHY, Arnott C, Mai W*, Huang Y*. Prognostic Value of Secreted Frizzled-Related Protein 5 in Heart Failure Patients With and Without Type 2 Diabetes Mellitus. Circ Heart Fail. 2020 Sep;13(9):e007054. (2021 年IF 10.447，JCR 1区，中科院小类1区)
  17. Cai X, Zhang Y, Li M, Wu JH, Mai L, Li J, Yang Y, Hu Y, Huang Y*. Association between prediabetes and risk of all cause mortality and cardiovascular disease: updated meta-analysis. BMJ. 2020 Jul 15;370:m2297. (2020 年IF 93.333，JCR 1区，中科院小类1区)
  18. Zhu H, Liang X, Pan XF, Huang C, Kuang J, Lv W, Zeng Q, Mai W, Huang Y*. A prospective cohort study of home blood pressure monitoring based on an intelligent cloud platform (the HBPM-iCloud study): rationale and design. Ther Adv Chronic Dis. 2020 Jun 10;11:2040622320933108. (2020 年IF 4.97，JCR 1区，中科院小类2区)
  19. Yang Y, Guo S*, Huang Z, Deng C, Chen L, Zhou G, Jian Z, He R, Huang Z, Yao Y, Lu J, Hua Z, Huang Y*. Decreased Mortality with Beta-Blocker Therapy in HFpEF Patients Associated with Atrial Fibrillation. Cardiol Res Pract. 2020 May 13;2020:3059864. (2021 年IF 1.99，JCR 4区，中科院小类4区)
  20. Yang S, Chen H, Tan K, Cai F, Du Y, Lv W, Hu Q, Hu Y*, Huang Y*. Secreted Frizzled-Related Protein 2 and Extracellular Volume Fraction in Patients with Heart Failure. Oxid Med Cell Longev. 2020 May 6;2020:2563508. (2021 年IF 7.31，JCR2区，中科院小类3区)
  21. Arnott C#, Huang Y#, Neuen B, Di Tanna GL, Cannon CP, Oh R, Edwards R, Kavalam M, Rosenthal N, Perkovic V, Jardine M, Mahaffey K, Neal B. The effect of canagliflozin on amputation risk in the CANVAS Program and the CREDENCE trial. Diabetes Obes Metab. 2020 Oct;22(10):1753-1766. (2021 年IF 6.408，JCR1区，中科院小类2区)
  22. Yang Y, Li W, Zhu H, Pan XF, Hu Y, Arnott C, Mai W, Cai X, Huang Y*. Prognosis of unrecognised myocardial infarction determined by electrocardiography or cardiac magnetic resonance imaging: systematic review and meta-analysis. BMJ. 2020 May 7;369:m1184. (2021 年IF 93.333，JCR 1区，中科院小类1区)
  23. Huang Y#, Dai M#, Deng Z#, Huang X, Li H, Bai Y, Yan C, Zhan Q, Zeng Q, Ouyang P, Xu D. Clustering of risk factors and the risk of new-onset hypertension defined by the 2017 ACC/AHA Hypertension Guideline. J Hum Hypertens. 2020 May;34(5):372-377. (2021 年IF 2.877，JCR 3区，中科院小类4区)
  24. Zheng S, Zheng H, Huang A, Mai L, Huang X, Hu Y, Huang Y*. Piwi-interacting RNAs play a role in vitamin C-mediated effects on endothelial aging. Int J Med Sci. 2020 Mar 26;17(7):946-952. (2021 年IF 3.642，JCR 2区，中科院小类3区)
  25. Cai X, Zheng S, Liu Y, Zhang Y, Lu J, Huang Y. Nonalcoholic fatty liver disease is associated with increased risk of atrial fibrillation. Liver Int. 2020 Jul;40(7):1594-1600. (2021 年IF 8.754，JCR 1区，中科院小类2区)
  26. Huang A, Zheng H, Wu Z, Chen M*, Huang Y*. Circular RNA-protein interactions: functions, mechanisms, and identification. Theranostics. 2020 Feb 10;10(8):3503-3517. (2021 年IF 11.6，JCR 1区，中科院小类1区)
  27. Wu Y, Liu X, Zheng H, Zhu H, Mai W, Huang X, Huang Y*. Multiple Roles of sFRP2 in Cardiac Development and Cardiovascular Disease. Int J Biol Sci. 2020 Jan 14;16(5):730-738. (2021 年IF 10.75，JCR 1区，中科院小类2区)
  28. Huang A, Huang Y*. Role of Sfrps in cardiovascular disease. Ther Adv Chronic Dis. 2020 Jan 28;11:2040622320901990. (2021 年IF 4.97，JCR 1区，中科院小类2区)
  29. Zhu H, Zheng H, Liu X, Mai W, Huang Y*. Clinical applications for out-of-office blood pressure monitoring. Ther Adv Chronic Dis. 2020 Jan 20;11:2040622320901660. (2021 年IF 4.97，JCR 1区，中科院小类2区)
  30. Lin M, Liu X, Zheng H, Huang X, Wu Y, Huang A, Zhu H, Hu Y, Mai W, Huang Y*. IGF-1 enhances BMSC viability, migration, and anti-apoptosis in myocardial infarction via secreted frizzled-related protein 2 pathway. Stem Cell Res Ther. 2020 Jan 9;11(1):22. (2021 年IF 8.097，JCR 1区，中科院小类2区)
  31. Liu Y, Wang S, Kan J, Zhang J, Zhou L, Huang Y*, Zhang Y*. Chinese Herbal Medicine Interventions in Neurological Disorder Therapeutics by Regulating Glutamate Signaling. Curr Neuropharmacol. 2020;18(4):260-276  (2021 年IF 7.708，JCR 1区，中科院小类1区)
  32. Mai L, Wu Y, Luo J, Liu X, Zhu H, Zheng H, Liang G, Zhang Y, Huang Y. A retrospective cohort study of oral anticoagulant treatment in patients with acute coronary syndrome and atrial fibrillation. BMJ Open. 2019 Sep 17;9(9):e031180. (2021 年IF 3.006，JCR 2区，中科院小类3区)
  33. Hu G, Liu D, Tong H, Huang W, Hu Y*, Huang Y*. Lipoprotein-Associated Phospholipase A2 Activity and Mass as Independent Risk Factor of Stroke: A Meta-Analysis. Biomed Res Int. 2019 May 20;2019:8642784. (2021 年IF 3.246，JCR 3区，中科院小类4区)
  34. Xu T#, Huang Y#, Zhou H, Bai Y, Huang X, Hu Y, Xu D, Zhang Y, Zhang J.β-blockers and risk of all-cause mortality in patients with chronic heart failure and atrial fibrillation-a meta-analysis. BMC Cardiovasc Disord. 2019 Jun 3;19(1):135. (2021 年IF 2.174，JCR 3区，中科院小类4区)
  35. Huang Y#, Deng Z#, Se Z, Bai Y, Yan C, Zhan Q, Zeng Q, Ouyang P, Dai M, Xu D. Combined impact of risk factors on the subsequent development of hypertension. J Hypertens. 2019 Apr;37(4):696-701. (2021 年IF 4.776，JCR 1区，中科院小类2区)
  36. Huang Y, Luo J, Liu X, Wu Y, Yang Y, Li W, Lv W, Hu Y. Gamma-Glutamyltransferase and Risk of Acute Coronary Syndrome in Young Chinese Patients: A Case-Control Study. Dis Markers. 2018 Sep 2;2018:2429160. (2021 年IF 3.464，JCR 2区，中科院小类3区)
  37. Huang Y, Wu Y, Yang Y, Li W, Lu J, Hu Y. Lipoprotein-associated phospholipase A2 and oxidized low-density lipoprotein in young patients with acute coronary syndrome in China. Sci Rep. 2017 Nov 23;7(1):16092. (2020 年IF 4.996，JCR 1区，中科院小类3区)
  38. Huang Y, Zhou H, Wu Y, Yang Y, Li W, Lu J, Hu Y. Soluble Urokinase Plasminogen Activator Receptor and the Risk of Coronary Artery Disease in Young Chinese Patients. Dis Markers. 2017:4719403. (2021 年IF 3.464，JCR 2区，中科院小类3区)
  39. Huang Y#, Huang W#, Mai W, Cai X, An D, Liu Z, Huang H, Zeng J, Hu Y, Xu D. White-coat hypertension is a risk factor for cardiovascular diseases and total mortality. J Hypertens. 2017 Apr;35(4):677-688. (2021 年IF 4.776，JCR 1区，中科院小类2区)
  40. Huang Y, Cai X, Mai W, Li M, Hu Y. Association between prediabetes and risk of cardiovascular disease and all cause mortality: systematic review and meta-analysis. BMJ. 2016 Nov 23;355:i5953. (2021年IF 93.333，JCR 1区，中科院小类1区)
  41. Xu T, Liu W, Cai X, Ding J, Tang H, Huang Y*, Hu Y*. Risk of Coronary Heart Disease in Different Criterion of Impaired Fasting Glucose: A Meta-Analysis. Medicine (Baltimore). 2015 Oct;94(40):e1740. (2021 年IF 1.817，JCR 2区，中科院小类4区)
  42. Xu S#, Huang Y#, Xiao J, Zhu W, Wang L, Tang H, Hu Y, Liu T. The association between job strain and coronary heart disease: A meta-analysis of prospective cohort studies. Ann Med. 2015 Sep;47(6):512-518. (2021 年IF 5.348，JCR 1区，中科院小类2区)
  43. Yang Y, Bi M, Xiao L, Chen Q, Chen W, Li W, Wu Y, Hu Y*, Huang Y*. Perceived stress status and sympathetic nervous system activation in young male patients with coronary artery disease in China. Eur J Intern Med. 2015;26(9):726-730. (2021 年IF 7.749，JCR 1区，中科院小类2区)
  44. Chen Y, Cai X, Huang W, Wu Y, Huang Y*, Hu Y*. Increased All-Cause Mortality Associated With Digoxin Therapy in Patients With Atrial Fibrillation: An Updated Meta-Analysis. Medicine (Baltimore). 2015 Dec;94(52):e2409. (2021 年IF 1.817，JCR 2区，中科院小类4区)
  45. Huang Y#, Xu S#, Hua J, Zhu D, Liu C, Hu Y, Liu T*, Xu D*. Association between job strain and risk of incident stroke: A meta-analysis. Neurology. 2015 Nov 10;85(19):1648-54. (2021 年IF 11.8，JCR 1区，中科院小类1区)
  46. Huang Y, Cai X, Liu C, Zhu D, Hua J, Hu Y, Peng J, Xu D. Prehypertension and the risk of coronary heart disease in Asian and Western populations: a meta-analysis. J Am Heart Assoc. 2015;19;4(2). pii: e001519  (2021 年IF6.106，JCR 2区，中科院小类2区)
  47. Huang Y, Cai X, Li Y, Su L, Mai W, Wang S, Hu Y, Wu Y, Xu D. Prehypertension and the risk of stroke: A meta-analysis. Neurology. 2014;82(13):1153-61 (2021 年IF 11.8，JCR 1区，中科院小类1区)
  48. Huang Y, Cai X, Zhang J, Mai W, Wang S, Hu Y, Ren H, Xu D. Prehypertension and Incidence of ESRD: A Systematic Review and Meta-analysis. Am J Kidney Dis. 2014;63(1):76-83. (2021 年IF 11.072，JCR 1区，中科院小类1区)
  49. Huang Y, Su L, Cai X, Mai W, Wang S, Hu Y, Wu Y, Tang H, Xu D. Association of all-cause and cardiovascular mortality with prehypertension: A meta-analysis. Am Heart J. 2014；167(2):160-168.e1. (2021 年IF5.099，JCR 2区，中科院小类3区)
  50. Huang Y#, Qiu W#, Liu C, Zhu D, Hua J, Cai X, Wu Y, Hu Y, Xu D. Prevalence and risk factors associated with prehypertension in Shunde District, southern China. BMJ Open. 2014;4(11):e006551  (2021年IF 3.006，JCR 2区，中科院小类3区)
  51. Huang Y, Cai X, Qiu M, Chen P, Tang H, Hu Y*, Huang Y*. Prediabetes and the risk of cancer: a meta-analysis. Diabetologia. 2014;57(11):2261-9. (2021 年IF 11.460，JCR 1区，中科院小类1区)
  52. Huang Y, Cai X, Chen P, Mai W, Tang H, Huang Y*, Hu Y*. Associations of prediabetes with all-cause and cardiovascular mortality: A meta-analysis. Ann Med. 2014;46(8):684-92  (2021 年IF 5.348，JCR 1区，中科院小类2区)
  53. Du Z#, Shen A#, Huang Y#, Su L, Lai W, Wang P, Xie Z, Xie Z, Zeng Q, Ren H, Xu D. 1H-NMR-based metabolic analysis of human serum reveals novel markers of myocardial energy expenditure in heart failure patients. Plos One. 2014;9(2):e88102.   (2021 年IF 3.752，JCR 1区，中科院小类3区)
  54. Huang Y, Wang S, Cai X, Mai W, Hu Y, Tang H, Xu D. Prehypertension and incidence of cardiovascular disease: a meta-analysis. BMC Med. 2013 ;11:177.  (2021 年IF 11.15，JCR 1区，中科院小类1区)
  55. Huang Y, Cai X, Song X, Tang H, Huang Y, Xie S, Hu Y. Steroids for preventing recurrence of acute severe migraine headaches: a meta-analysis. Eur J Neurol. 2013;20(8):1184-1190. (2021 年IF6.288，JCR 1区，中科院小类2区)
  56. Wu Y#, Huang Y#, Hu Y, Zhong J, He Z, Li W, Yang Y, Xu D, Wu S. Hyperhomocysteinemia is an independent risk factor in young patients with coronary artery disease in southern China. Herz. 2013;38(7):779-84. (2021 年IF 1.74，JCR 4区，中科院小类4区)
  57. Huang YL, Kuang J, Hu YZ, Song YB, Qiu RF, Mai WY. Bone marrow stromal cell transplantation combined with angiotensin-converting enzyme inhibitor treatment in rat with acute myocardial infarction and the role of insulin-like growth factor-1. Cytotherapy. 2012. 14(5): 563-569.  (2021 年IF 6.196，JCR 1区，中科院小类2区)
  58. Huang Y, Qiu R, Mai W, Kuang J, Cai X, Dong Y, Hu Y, Song Y, Cai A, Jiang Z. Effects of insulin-like growth factor-1 on the properties of mesenchymal stem cells in vitro. J Zhejiang Univ Sci B. 2012. 13(1): 20-8.  (2021 年IF 5.552，JCR 3区，中科院小类3区)
  59. Huang Y, Mai W, Cai X, Hu Y, Song Y, Qiu R, Wu Y, Kuang J. The effect of zolpidem on sleep quality, stress status, and nondipping hypertension. Sleep Med. 2012. 13(3): 263-268.  (2021 年IF4.842，JCR 2区，中科院小类3区)
  60. Huang Y, Hu Y, Mai W, Cai X, Song Y, Wu Y, Dong Y, Huang H, He Z, Li W, Yang Y, Rao S. Plasma oxidized low-density lipoprotein is an independent risk factor in young patients with coronary artery disease. Dis Markers. 2011. 31(5): 295-301. (2020 年IF 3.464，JCR 2区，中科院小类3区)
  61. Huang Y, Mai W, Hu Y, Wu Y, Song Y, Qiu R, Dong Y, Kuang J. Poor sleep quality, stress status, and sympathetic nervous system activation in nondipping hypertension. Blood Press Monit. 2011. 16(3): 117-123.  (2020 年IF1.43，JCR 4区，中科院小类4区)
  62. Huang Y, Song Y, Mai W, Hu Y, Cai X, Wu Y, Qiu R, Kuang J. Association of N-terminal pro brain natriuretic peptide and impaired aortic elastic property in hypertensive patients. Clin Chim Acta. 2011. 412(23-24): 2272-2276. (2021 年IF6.314，JCR 2区，中科院小类2区)