南方医科大学高层次引进人才，现为南方医科大学珠江医院心脏中心实验室独立PI，硕士生导师，广东省心血管疾病生物医学工程研究中心生物材料课题组负责人。担任广东省药理学会心血管专委会常委，广东省病生学会心血管青年专委会委员，Nanoscale、Biomaterial Science、Chemical communications等国际期刊审稿人，以第一作者/通讯作者（含共同）在Journal of the American Chemical Society, Angewandte Chemie International Edition, Biomaterials, Bioactive Materials, Theranostics, Chemical Engineering journal，ACS Applied Materials & Interfaces等国际知名期刊发表SCI论文20余篇，其中影响因子大于10的论文7篇，单篇最高他引190次，2篇论文被Web of Science列为高引论文。以第一负责人承担国家自然科学基金2项，广东省自然科学基金2项，申请国家发明专利4项。

课题组主要从事小分子多肽自组装体系及其生物医学应用的研究，近年来课题组在以下三个方向1）多肽水凝胶结合干细胞疗法在心肌梗死治疗中的应用； 2）基于功能多肽的自组装纳米材料在心血管疾病治疗机制中的研究；3）基于多肽自组装的多组分纳米复合药物在细胞器靶向运输和调控细胞功能上的应用。奠定了扎实的研究基础，取得一系列有价值的研究成果。

• Jie Zhan, Xu Liao, Xianglin Fan, Jianwu Zhang, Hekai Li, Yanbin Cai*, Xiaozhong Qiu*, An injectable and conductive TEMPOL/polypyrrole integrated peptide coassembly hydrogel promotes functional maturation of cardiomyocytes for myocardial infarction repair. Composites Part B: Engineering, 2022, 236, 109794.
• Xianglin Fan#, Jie Zhan#, Xianmei Pan, Xu Liao, Wenjie Guo, Peier Chen, Hekai Li, Weijing Feng, Yanbin Cai*, Minsheng Chen*, Enzymatic self-assembly nanofibers anchoring mesenchymal stem cells induce cell spheroids and amplify paracrine function for myocardial infarction therapy. Chemical Engineering Journal, 2022, 436, 135224.
• J. Zhan, Y. Wang, S. Ma, Q. Qin, L. Wang, Yanbin Cai*, Z. Yang*, Organelle-inspired supramolecular nanomedicine to precisely abolish liver tumor growth and metastasis. Bioactive Materials, 2022, 9, 120-133.
• H. Li#, B. Yu#, P. Yang#, J. Zhan, X. Fan, P. Chen, X. Liao, C. Ou*, Yanbin Cai*, and M. Chen*, Injectable AuNP-HA matrix with localized stiffness enhances the formation of gap junction in engrafted human induced pluripotent stem cell-derived cardiomyocytes and promotes cardiac repair. Biomaterials, 2021, 279, 121231.
• W. Guo#, W. Feng#, J. Huang, J. Zhang, X. Fan, S. Ma, M. Li, J. Zhan,* Yanbin Cai,* M. Chen*, Supramolecular self-assembled nanofibers efficiently activate the precursor of hepatocyte growth factor for angiogenesis in myocardial infarction therapy. ACS Appl. Mater. Interfaces, 2021, 13, 22131-22141.
• Z. Wen#, J. Zhan#, H. Li, G. Xu, S. Ma, J. Zhang, Z. Li, C. Ou, Z. Yang*, Yanbin Cai*, M. Chen*, Dual-ligand supramolecular nanofibers inspired by the renin-angiotensin system for the targeting and synergistic therapy of myocardial infarction. Theranostics, 2021, 11, 3725-3741.
• Y. Zhong, J. Zhan*, G. Xu, Y. Chen, Q. Qin, X. Liao, S. Ma, Z. Yang*, Yanbin Cai*, Enzyme Instructed Self-assembly Enabled Monomer-excimer Transition to Construct Higher Ordered Luminescent Supramolecular Assembly for Activity-based Bioimaging. Angew. Chem. Int. Ed. 2021, 60, 8121-8129.
• C. Fu‡, J, Zhan‡, J. Huai, S. Ma, M. Li, G. Chen, M. Chen*, Yanbin Cai*, Caiwen Ou*, Furin-Instructed Molecular Self-Assembly Actuates Endoplasmic Reticulum Stress-Mediated Apoptosis for Cancer Therapy. Nanoscale, 2020, 12, 12126-12132.
• J. Zhan‡, J. Zhong‡, S. Ma, W. Ma, Y. Wang, Z. Yu, Yanbin Cai*, W. Huan*, Dual-responsive self-assembly in lysosomes enables cell cycle arrest for locking glioma cell growth. Chem. Commun. 2020, 56, 6957-6960.
• H. Mo‡, C. Fu‡, Z. Wu, P. Liu, Z. Wen, Q. Hong, Yanbin Cai*, Gongxin Li*, IL-6-targeted ultrasmall superparamagnetic iron oxide nanoparticles for optimized MRI detection of atherosclerotic vulnerable plaques in rabbits. RSC Adv. 2020, 10, 15346–15353.
• T. Xu‡, Yanbin Cai‡, X. Zhong, L. Zhang, D. Zheng, Z. Gao, X. Pan, F. Wang*, M. Chen*, Z. Yang*, β-Galactosidase instructed supramolecular hydrogelation for selective identification and removal of senescent cells. Chem. Commun. 2019, 55, 7175-7178.
• J. Zhan, Yanbin Cai, S. He, L. Wang, Z. Yang, Tandem Molecular Self-Assembly in Liver Cancer Cells. Angew. Chem., Int. Ed. 2018, 57, 1813-1816.
• Yanbin Cai‡, J. Zhang‡, Y. He, Z. Li, Y. Hua, Z. Wu, J. Gao, C. Ou*, M. Chen*, A Supramolecular Hydrogel of Puerarin. J. Biomed. Nanotechnol. 2018, 14, 257–266.
• J. Zhan‡, Yanbin Cai‡, S. Ji, Y. Shang, J. Gao*, Z. Yang*, Supramolecular silk from a peptide hydrogel. Mater. Chem. Front. 2017. 1, 911-915.
• Yanbin Cai, H. Shen, J. Zhan, M. Lin, L. Dai, C. Ren, Y. Shi, J. Liu*, J. Gao*, Z. Yang*, Supramolecular "Trojan Horse" for Nuclear Delivery of Dual Anticancer Drugs. J. Am. Chem. Soc. 2017, 139, 2876-2879.
• Yanbin Cai, J. Zhan, H. Shen, D. Mao, S. Ji, R. Liu, B. Yang, D. Kong, L. Wang*, Z. Yang*, Optimized Ratiometric Fluorescent Probes by Peptide Self-Assembly. Anal. Chem. 2016, 88, 740-745.
• Yanbin Cai, Y. Shi, H. Wang, J. Wang, D. Ding, L. Wang*, Z. Yang*, Environment-Sensitive Fluorescent Supramolecular Nanofibers for Imaging Applications. Anal. Chem. 2014, 86, 2193-2199.