陈婷,南方医科大学南方医院儿童口腔负责人,医学博士,博士后,副主任医师,硕士生导师,美国TUFTS大学访问学者,现任中华口腔医学会老年口腔专业委员会委员、中华口腔医学会口腔激光医学专业委员会委员和中华口腔医学会牙体牙髓专业委员会青年委员。
擅长儿童口腔疾病的综合诊治及儿童口腔的舒适化治疗,在儿童乳牙牙体牙髓疾病的序列诊治、乳牙残冠修复及乳牙早期矫治等方面有着丰富和独到的经验。
主持国家自然科学基金1项,校级以上课题12项。发表中英文论文30余篇,其中第一作者及通讯作者文章18篇,最新成果已被药物化学顶刊《JOURNAL OF MEDICINAL CHEMISTRY》收录。参与制定一项关于《口腔诊疗适度镇静/镇痛》的专家共识。授权国家发明专利1项。
主要研究领域为牙髓血运重建、口腔遗传疾病、口腔激光治疗、口腔疾病的新药研发等。
近3年代表性论文
[1] Huang J#, Ma Z#, Peng X#, Yang Z, Wu Y, Zhong G, Ouyang T, Chen Z, Liu Y, Wang Q, Chen J*, Chen T*, Zeng Z*. Discovery of Novel Potent and Fast BTK PROTACs for the Treatment of Osteoclasts-Related Inflammatory Diseases. J Med Chem. 2024 Feb 22;67(4):2438-2465.(IF=7.3,一区,药物化学顶刊)
[2] Zeng M#, Yao X#, Pan Y, Gu H, Xiong F, Yin X*, Wu B*, Chen T*. A novel APC mutation associated with Gardner syndrome in a Chinese family. Gene. 2024 Feb 20;896:148051.(IF=3.5,二区)
[3] Li J, Liang J, Chen S, Guo W, Chen T*, Liu X*. A Janus adhesive hydrogel sheet for preventing postoperative tissue adhesion of intestinal injuries. RSC Adv. 2024 Feb 1;14(7):4416-4423.(IF=3.9,二区)
[4] Huang J#, Ma Z#, Yang Z, He Z, Bao J, Peng X, Liu Y, Chen T*, Cai S*, Chen J*, Zeng Z*. Discovery of Ibrutinib-based BTK PROTACs with in vivo anti-inflammatory efficacy by inhibiting NF-κB activation. Eur J Med Chem. 2023 Nov 5;259:115664.(IF=6.7,一区)
[5] Liu W#, Qiu W#, Huang Z, Zhang K, Wu K, Deng K, Chen Y, Guo R, Wu B*, Chen T*, Fang F*. Identification of nine signature proteins involved in periodontitis by integrated analysis of TMT proteomics and transcriptomics. Front Immunol. 2022 Aug 9;13:963123.(IF=8.8,二区)
[6] Li L#, Yuan S#, Lin L, Yang F, Liu T, Xu C, Zhao H, Chen J, Kuang P, Chen T*, Liao W*, Chen J*. Discovery of novel 2-aryl-4-bis-amide imidazoles (ABAI) as anti-inflammatory agents for the treatment of inflammatory bowel diseases (IBD). Bioorg Chem. 2022 Mar;120:105619.(IF=5.3,小类一区)