南方医科大学药学院教授、博导。专注于非编码RNA抗肿瘤相关领域的研究，以第一和通讯作者在国际杂志发表研究论文(SCI)30余篇，包括国际著名杂志(FU WM，et al. 2019, Genome Biology; FU WM et al. 2015, J Hepatology; FU WM et al. 2017, Oncogene; FU WM et al. 2018, Mol Ther- Nucleic Acid )等，总影响因子超过300，总引用次数达1000余次。
学习经历：
1994.09-1998.07山东师范大学，食品科学与工程，学士
2001.07-2003.07天津大学，生物化工，硕士
2010.08-2012.12香港中文大学，生物医学，博士
工作经历：
1998.08-2001.06山东省济南市轻工业学校，教师
2003.03-2006.12天津天士力药业，研发主管
2007.01-2010.03VeoliawaterSolutionandTechnology（SH），技术经理
2012.03-2012.08美国耶鲁大学药理学，访问学者
2012.12-2016.03广州中国科学院先进技术研究所，实验室主任，副研究员
2016.03-至今南方医科大学药学院，教授
主要科研课题：
1.国家自然科学基金。81773066。基于调控转录因子FOXA2的长链非编码RNA在肝癌转移复发中的作用及分子机制研究。2018.01-2021.12。主持人
2. 广东省自然科学基金。2020A1515010961。基于调控肿瘤干细胞的长链非编码RNA lincROR在肝癌转移复发中的功能及分子机理研究。2019.10-2022。主持人
3. 广东省自然科学基金。2021A1515012111。HOTTIP/METTL3/DKK1信号轴在调控肝癌发生发展中的功能及分子机制研究。2021.1-2023.12。主持人
4.广东省自然科学基金。2015A030310139。长链非编码RNAH19调控结肠癌中甲氨蝶呤的耐药性及其分子机理的研究。2015.8～2018.7。主持人
5.广州市科技计划项目。2014J410OO45。调控神经胶质瘤中Trail耐受性的microRNAs及其分子机制的研究。2014.1～2016.6。主持人
6.国家自然科学基金项目。81372450。MiRNA-133a调控神经胶质瘤中TRAIL耐受性及分子机制研究。2014.1～2017.12。第二参与人
7.国家自然科学基金。81201699。沉默原癌基因Bmi-1的microRNAs在原发性肝癌中的功能及分子机制研究。2013.1～2015.12。第二参与人
8.教育部留学人员资助项目。20151312。主持人
授权专利：
1.付卫明、张锦芳、梁岩。一种调控肿瘤对TRAIL耐受性的药物。中国。ZL201310089306.4
2.付卫明、张锦芳。MicroRNA用于制备降低神经胶质瘤对TRAIL耐受性的药物的用途。中国。ZL201410165917.7
3.付卫明、梁伟铖。LincRNA在制备调控甲氨蝶呤肿瘤治疗耐药性的药物中的应用。2013.11。中国。Zl201310611737.2
1. Wei-Ming F, Xiao Z, Wei-Mao W, Ying-Fei L, Bao-Guang H, Hua W, et al. Hotair mediates hepatocarcinogenesis through suppressing miRNA-218 expression and activating P14 and P16 signaling. Journal of Hepatology (if, 25.083).2015.
2. Jin-fang Z, Ming-liang H, Wei-ming F, Hua W, Lian-zhou C, Xiao Z, et al. Primate-specific microRNA-637 inhibits tumorigenesis in hepatocellular carcinoma by disrupting signal transducer and activator of transcription 3 signaling. Hepatology (if; 17.425). 2011.
3. Wei-Cheng L, Cheuk-Wa W, Pu-Ping L, Mai S, Ye C, Shi-Tao R, et al. Translation of the circular RNA circβ-catenin promotes liver cancer cell growth through activation of the Wnt pathway. Genome biology (if; 13.583). 2019.
4. Wei-Cheng L, Jia-Lin R, Cheuk-Wa W, Sun-On C, Mary Miu-Yee W, Wei-Ming F, et al. LncRNA-NEF antagonized epithelial to mesenchymal transition and cancer metastasis via cis-regulating FOXA2 and inactivating Wnt/β-catenin signaling. Oncogene (if; 9.867). 2018.
5. Weicheng L, Chuanjian S, Weilong H, Panlong L, Xue Z, Weiming F, et al. Super-enhancer-driven lncRNA-DAW promotes liver cancer cell proliferation through activation of Wnt/β-catenin pathway. Molecular Therapy - Nucleic Acids (if; 8.8). 2021.
6. Wei-Ming F, Li-Peng T, Xiao Z, Ying-Fei L, Yan-Ling Z, Wayne Yuk-Wai L, et al. MiR-218-targeting-Bmi-1 mediates the suppressive effect of 1,6,7-trihydroxyxanthone on liver cancer cells. Apoptosis : an international journal on programmed cell death. 2014.
7. Chuan-jian S, Yan-biao Z, Fei-fei P, Feng-wei Z, Peng Z, Wei-ming F. Gallic Acid Suppressed Tumorigenesis by an LncRNA MALAT1-Wnt/β-Catenin Axis in Hepatocellular Carcinoma. Frontiers in pharmacology. 2021.
8. Fei-fei P, Jiang S, Chuan-jian S, Zhi-peng L, Wei-ming F, Jin-fang Z. Apigenin promotes osteogenic differentiation of mesenchymal stem cells and accelerates bone fracture healing via activating Wnt/β-catenin signaling. American Journal of Physiology-Endocrinology and Metabolism. 2021.
9. Fei-fei P, Yan-Biao Z, Chuan-Jian S, Feng-wei Z, Jin-fang Z, Wei-ming F. H19-Wnt/β-catenin regulatory axis mediates the suppressive effects of apigenin on tumor growth in hepatocellular carcinoma. European Journal of Pharmacology. 2020.
10. Jiang S, Chuan-Jian S, Yun L, Feng-Wei Z, Fei-Fei P, Wei-Ming F, et al. LincROR Mediates the Suppressive Effects of Curcumin on Hepatocellular Carcinoma Through Inactivating Wnt/β-Catenin Signaling. Frontiers in pharmacology. 2020.
11. Jin-fang Z, Wei-ming F, Ming-liang H, Hua W, Wei-mao W, Shi-cang Y, et al. MiR-637 maintains the balance between adipocytes and osteoblasts by directly targeting Osterix. Molecular Biology of the Cell. 2011.
12. Jin-fang Z, Wei-ming F, Ming-liang H, Wei-dong X, Qing L, Gang W, et al. MiRNA-20a promotes osteogenic differentiation of human mesenchymal stem cells by co-regulating BMP signaling. RNA Biology. 2011.
13. Ke-Feng W, Wei-Cheng L, Lu F, Jian-Xin P, Mary Miu-Yee W, Jin-Fang Z, et al. H19 mediates methotrexate resistance in colorectal cancer through activating Wnt/β-catenin pathway. Experimental Cell Research. 2016.
14. Min-Yi L, Chuan-Jian S, Fei-Fei P, Jiang S, Lu F, Guoqin C, et al. Urolithin B suppresses tumor growth in hepatocellular carcinoma through inducing the inactivation of Wnt/β-catenin signaling. Journal of Cellular Biochemistry. 2019.
15. Rui-Lian X, Wan H, Jun T, Wei G, Peng Z, Chang-Qing W, et al. Primate-specific miRNA-637 inhibited tumorigenesis in human pancreatic ductal adenocarcinoma cells by suppressing Akt1 expression. Experimental Cell Research. 2018.
16. Wei-Cheng L, Wei-Ming F, Cheuk-Wa W, Yan W, Wei-Mao W, Guo-Xin H, et al. The lncRNA H19 promotes epithelial to mesenchymal transition by functioning as miRNA sponges in colorectal cancer. Oncotarget. 2015.
17. Wei-Cheng L, Wei-Ming F, Yu-Bing W, Yu-Xin S, Liang-Liang X, Cheuk-Wa W, et al. H19 activates Wnt signaling and promotes osteoblast differentiation by functioning as a competing endogenous RNA. Scientific Reports. 2016.
18. Wei-ming F, Jin-fang Z, Hua W, Hong-sheng T, Wei-mao W, Shih-Chi C, et al. Apoptosis induced by 1,3,6,7-tetrahydroxyxanthone in Hepatocellular carcinoma and proteomic analysis. Apoptosis : an international journal on programmed cell death. 2012.
19. Wei-ming F, Jin-fang Z, Hua W, Zhi-chao X, Wei-mao W, Peng Z, et al. Heat shock protein 27 mediates the effect of 1,3,5-trihydroxy-13,13-dimethyl-2H-pyran [7,6-b] xanthone on mitochondrial apoptosis in hepatocellular carcinoma. Journal of Proteomics. 2012.
20. Wei-Ming F, Wei-Mao W, Hua W, Xiao Z, Yan L, Hsiang-Fu K, et al. 1,3,5-Trihydroxy-13,13-dimethyl-2H-pyran [7,6-b] xanthone directly targets heat shock protein 27 in hepatocellular carcinoma. Cell Biology International. 2013.
21. Wei-ming F, Xiao Z, Hua W, Wei-Mao W, Ju-yu C, Yan L, et al. Staphylococcal enterotoxin C2 promotes osteogenesis and suppresses osteoclastogenesis of human mesenchymal stem cells. Experimental Cell Research. 2013.
22. Wei-Ming F, Ying-Fei L, Bao-Guang H, Wei-Cheng L, Xiao Z, Hai-di Y, et al. Long noncoding RNA Hotair mediated angiogenesis in nasopharyngeal carcinoma by direct and indirect signaling pathways. Oncotarget. 2015.
23. Yi L, Yan L, Jin-Fang Z, Wei-Ming F. MicroRNA-133 mediates cardiac diseases: Mechanisms and clinical implications. Experimental Cell Research. 2017.
24. Ying-fei L, Li Z, Mary Miu Yee W, Wei-ming F, Jin-fang Z. MiR-218 mediates tumorigenesis and metastasis: Perspectives and implications. Experimental Cell Research. 2015.