南方医科大学第十附属医院（东莞市人民医院）肝胆胰外科主任兼红楼院区肝胆胰外科主任。“东莞名医”人才项目入选者，东莞市第三类特色人才。从事肝胆胰外科的临床、科研、教学工作28年，擅长各种肝胆胰脾疾病的诊断和治疗。担任中华医学会外科学分会青年委员、中华医学会外科学分会第十七胰腺外科组委员、中国医疗保健国际交流促进会（医促会）胰腺疾病分会委员、中国医疗保健国际交流促进会（医促会）胰腺疾病分会，胰腺疾病微创治疗学组委员、中国研究型医院学会胰腺疾病专业委员会及微创胰腺治疗学组委员、中国医师协会胰腺癌专业委员会委员、中国医师协会外科医师分会加速康复外科委员会、中国医学装备协会基础装备分会委员、中国抗癌协会肿瘤标志专业委员会非编码RNA与肿瘤研究专委会常委、湖北省抗癌协会胰腺癌专业委员常委；《中华内分泌外科杂志》编委，《中华肝胆外科杂志》通讯编委、《中国普通外科杂志》常务编委。作为项目负责人承担国家自然科学基金4 项、中国博士后基金 1项、省市级基金课题等 4 项。参与国家科技部国际科技合作项目，以第一作者/通讯作者发表SCI论文56篇。
目前在研课题经费：
1.国家自然科学基金面上项目（No.82372948）经费：49万（医院配套49万）
2.2023年东莞市社会发展科技项目高水平医院建设专项（No.20231800932482）经费：300万
3.2023年“东莞名医”人才引进培养项目 经费：80万
部分发表的SCI收录文章：
[1] Zhang D, He Z, Shen Y, Wang J, Liu T, Jiang J. MiR-489-3p Reduced Pancreatic Cancer Proliferation and Metastasis By Targeting PKM2 and LDHA Involving Glycolysis. Front Oncol. 2021. 11: 651535.
[2] Zhou X, Guo X, Chen M, Xie C, Jiang J. HIF-3α Promotes Metastatic Phenotypes in Pancreatic Cancer by Transcriptional Regulation of the RhoC-ROCK1 Signaling Pathway. Mol Cancer Res. 2018. 16(1): 124-134.
[3] Chen P, He Z, Wang J, et al. Hypoxia-Induced ZWINT Mediates Pancreatic Cancer Proliferation by Interacting With p53/p21. Front Cell Dev Biol. 2021. 9: 682131.
[4] Zeng Z, Lei S, He Z, Chen T, Jiang J. YEATS2 is a target of HIF1α and promotes pancreatic cancer cell proliferation and migration. J Cell Physiol. 2021. 236(3): 2087-2098.
[5] Jiang J, Yu C, Guo X, et al. G Protein-Coupled Receptor GPR87 Promotes the Expansion of PDA Stem Cells through Activating JAK2/STAT3. Mol Ther Oncolytics. 2020. 17: 384-393.
[6] Chen Y, Xu S, Liu X, Jiang X, Jiang J. CircSEC24A upregulates TGFBR2 expression to accelerate pancreatic cancer proliferation and migration via sponging to miR-606. Cancer Cell Int. 2021. 21(1): 671.
[7] Jiang X, Wang J, Chen P, et al. [6]-Paradol suppresses proliferation and metastases of pancreatic cancer by decreasing EGFR and inactivating PI3K/AKT signaling. Cancer Cell Int. 2021. 21(1): 420.
[8] Xu J, Xu J, Liu X, Jiang J. The role of lncRNA-mediated ceRNA regulatory networks in pancreatic cancer. Cell Death Discov. 2022. 8(1): 287.
[9] Xu J, Quan G, Huang W, Jiang J. VSIG2 promotes malignant progression of pancreatic ductal adenocarcinoma by enhancing LAMTOR2-mediated mTOR activation. Cell Commun Signal. 2023. 21(1): 223.
[10] Wang J, Guo X, Xie C, Jiang J. KIF15 promotes pancreatic cancer proliferation via the MEK-ERK signalling pathway. Br J Cancer. 2017. 117(2): 245-255.
[11] He Z, Wang J, Xu J, Jiang X, Liu X, Jiang J. Dynamic regulation of KIF15 phosphorylation and acetylation promotes focal adhesions disassembly in pancreatic cancer. Cell Death Dis. 2022. 13(10): 896.
[12] Quan G, Xu J, Wang J, Liu X, Xu J, Jiang J. KIF15 is essential for USP10-mediated PGK1 deubiquitination during the glycolysis of pancreatic cancer. Cell Death Dis. 2023. 14(2): 137.
[13] Wang J, He Z, Liu X, et al. LINC00941 promotes pancreatic cancer malignancy by interacting with ANXA2 and suppressing NEDD4L-mediated degradation of ANXA2. Cell Death Dis. 2022. 13(8): 718.
[14] Xu J, Wang J, He Z, et al. LncRNA CERS6-AS1 promotes proliferation and metastasis through the upregulation of YWHAG and activation of ERK signaling in pancreatic cancer. Cell Death Dis. 2021. 12(7): 648.
[15] Wang J, He Z, Xu J, Chen P, Jiang J. Long noncoding RNA LINC00941 promotes pancreatic cancer progression by competitively binding miR-335-5p to regulate ROCK1-mediated LIMK1/Cofilin-1 signaling. Cell Death Dis. 2021. 12(1): 36.
[16] Liu X, Xu J, Shen B, Xu J, Jiang J. USP33 promotes pancreatic cancer malignant phenotype through the regulation of TGFBR2/TGFβ signaling pathway. Cell Death Dis. 2023. 14(6): 362.
[17] Li X, Liang M, Jiang J, et al. Combined inhibition of autophagy and Nrf2 signaling augments bortezomib-induced apoptosis by increasing ROS production and ER stress in pancreatic cancer cells. Int J Biol Sci. 2018. 14(10): 1291-1305.
[18] He Z, Wang J, Zhu C, et al. Exosome-derived FGD5-AS1 promotes tumor-associated macrophage M2 polarization-mediated pancreatic cancer cell proliferation and metastasis. Cancer Lett. 2022. 548: 215751.
[19] Lei S, He Z, Chen T, et al. Long noncoding RNA 00976 promotes pancreatic cancer progression through OTUD7B by sponging miR-137 involving EGFR/MAPK pathway. J Exp Clin Cancer Res. 2019. 38(1): 470.
[20] He Z, Guo X, Tian S, et al. MicroRNA-137 reduces stemness features of pancreatic cancer cells by targeting KLF12. J Exp Clin Cancer Res. 2019. 38(1): 126.
[21] Guo X, Zheng L, Jiang J, et al. Blocking NF-κB Is Essential for the Immunotherapeutic Effect of Recombinant IL18 in Pancreatic Cancer. Clin Cancer Res. 2016. 22(23): 5939-5950.
[22] Wang M, Liu J, Zhao Y, et al. Upregulation of METTL14 mediates the elevation of PERP mRNA N(6) adenosine methylation promoting the growth and metastasis of pancreatic cancer. Mol Cancer. 2020. 19(1): 130.